Human MICA/B PE-conjugated Antibody | R&D Systems FAB13001P-025 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human MICA/B PE-conjugated Antibody

catalog :

FAB13001P-025

quantity :

25 Tests (also 100 Tests)

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

159207

reactivity :

human

application :

flow cytometry, FACS

more info or order :

R&D Systems product webpage

citations: 7

Reference
Lee S, Chae S, Jang I, Oh S, Kim S, Lee S, et al. B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies. EBioMedicine. 2024;110:105459 pubmed publisher
Duan Q, Li H, Gao C, Zhao H, Wu S, Wu H, et al. High glucose promotes pancreatic cancer cells to escape from immune surveillance via AMPK-Bmi1-GATA2-MICA/B pathway. J Exp Clin Cancer Res. 2019;38:192 pubmed publisher
Morisaki T, Hirano T, Koya N, Kiyota A, Tanaka H, Umebayashi M, et al. NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors. Anticancer Res. 2014;34:4529-38 pubmed
Umebayashi M, Kiyota A, Koya N, Tanaka H, Onishi H, Katano M, et al. An epithelial cell adhesion molecule- and CD3-bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro. Anticancer Res. 2014;34:4509-19 pubmed
Yamanegi K, Yamane J, Kobayashi K, Kato Kogoe N, Ohyama H, Nakasho K, et al. Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma cells to Fas- and NK cell-mediated cell death. Int J Oncol. 2012;41:83-91 pubmed publisher
Morisaki T, Onishi H, Koya N, Kiyota A, Tanaka H, Umebayashi M, et al. Combinatorial cytotoxicity of gemcitabine and cytokine-activated killer cells in hepatocellular carcinoma via the NKG2D-MICA/B system. Anticancer Res. 2011;31:2505-10 pubmed
Qin H, Lee I, Panagiotopoulos C, Wang X, Chu A, Utz P, et al. Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling. Diabetes. 2011;60:857-66 pubmed publisher

product information

master code :

FAB13001P

SKU :

FAB13001P-025

product name :

Human MICA/B PE-conjugated Antibody

unit size :

25 Tests (also 100 Tests)

description :

The Human MICA/B PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to MICA/B. This antibody reacts with human. The Human MICA/B PE-conjugated Antibody has been validated for the following applications: FACS,Flow Cytometry.

target :

MICA/B

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

159207

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

BaF3 mouse pro-B cell line transfected with human MICA, Accession # Q29983

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human MICA/B in direct ELISAs.

gene symbol :

MICA

top caption :

Detection of MICA/B antibody in K562 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q29983

applications :

FACS,Flow Cytometry

USD :

149 USD

alt names :

MHC class I chain-related protein A, MHC class I chain-related protein B, MIC, MICA, MICB, PERB11, PERB11.1, PERB11.2

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage