product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TREM-1 PE-conjugated Antibody
catalog :
FAB1278P
quantity :
100 Tests
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
193015
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 11
Reference
da Silva Neto P, de Carvalho J, Pimentel V, P xe9 rez M, Toro D, Fraga Silva T, et al. sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity. Viruses. 2021;13: pubmed publisher
Kluckova K, Kozak J, Szaboova K, Rychly B, Svajdler M, Suchánková M, et al. TREM-1 and TREM-2 Expression on Blood Monocytes Could Help Predict Survival in High-Grade Glioma Patients. Mediators Inflamm. 2020;2020:1798147 pubmed publisher
Suchánková M, Urban J, Ganovska M, Tibenska E, Szaboova K, Tedlova E, et al. TREM-1 and TREM-2 Expression on CD14+ Cells in Bronchoalveolar Lavage Fluid in Pulmonary Sarcoidosis and Hypersensitivity Pneumonitis in the Context of T Cell Immune Response. Mediators Inflamm. 2020;2020:9501617 pubmed publisher
Hyun J, McMahon R, Lang A, Edwards J, Badilla A, Greene M, et al. HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells. PLoS Pathog. 2019;15:e1007883 pubmed publisher
Wu Y, Fang Y, Ding L, Liu X, Francisco N, Wen J, et al. Activation and Regulation of Blood Vδ2 T Cells Are Amplified by TREM-1+ during Active Pulmonary Tuberculosis. J Immunol. 2018;200:1627-1638 pubmed publisher
Sierra Díaz E, Bravo Cuellar A, Ortiz Lazareno P, Garcia Gutierrez M, Georgina H, Anaya Prado R. Urine TREM-1 as a marker of urinary tract infection in children. J Int Med Res. 2017;45:631-638 pubmed publisher
Zhang G, Liu H, Huang J, Chen S, Pan X, Huang H, et al. TREM-1low is a novel characteristic for tumor-associated macrophages in lung cancer. Oncotarget. 2016;7:40508-40517 pubmed publisher
Oku R, Oda S, Nakada T, Sadahiro T, Nakamura M, Hirayama Y, et al. Differential pattern of cell-surface and soluble TREM-1 between sepsis and SIRS. Cytokine. 2013;61:112-7 pubmed publisher
Gómez Piña V, Martínez E, Fernández Ruíz I, del Fresno C, Soares Schanoski A, Jurado T, et al. Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM-1-PI3K-NF-?B pathway. J Leukoc Biol. 2012;91:933-45 pubmed publisher
Bosco M, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, et al. Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo. Blood. 2011;117:2625-39 pubmed publisher
Fortin C, Lesur O, Fulop T. Effects of TREM-1 activation in human neutrophils: activation of signaling pathways, recruitment into lipid rafts and association with TLR4. Int Immunol. 2007;19:41-50 pubmed
product information
master code :
FAB1278P
SKU :
FAB1278P
product name :
Human TREM-1 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human TREM-1 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to TREM1. This antibody reacts with human. The Human TREM-1 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry,Knockout Validated.
target :
TREM-1
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
193015
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human TREM-1, Ala21-Asn205, Accession # Q9NP99
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human TREM-1 in ELISAs.
gene symbol :
TREM1
top caption :
Detection of TREM-1 antibody in Human Blood Granulocytes antibody by Flow Cytometry.
accessionNumbers :
Q9NP99
applications :
Flow Cytometry,Immunocytochemistry,Knockout Validated
extended description :
Clone 193015 was used by HLDA to establish CD designation
USD :
399 USD
product details :
Clone 193015 was used by HLDA to establish CD designation
alt names :
CD354, CD354 antigen, TREM1, TREM-1Triggering receptor expressed on monocytes 1, triggering receptor expressed on myeloid cells 1, triggering-receptor TREM1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.