This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human NKG2A/CD159a PE-conjugated Antibody
catalog :
FAB1059P
quantity :
25 Tests (also 100 Tests)
price :
129 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
131411
reactivity :
human
application :
flow cytometry
citations: 25
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1e
Loyon R, Picard E, Mauvais O, Queiroz L, Mougey V, Pallandre J, et al. IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner. J Immunol. 2016;197:85-96 pubmed publisher
Yu M, Pan H, Che N, Li L, Wang C, Wang Y, et al. Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cells. Cell Mol Immunol. 2020;: pubmed publisher
Vela M, del Rosal T, Perez Martinez A, Valentín J, Casas I, Pozo F, et al. Possible role of highly activated mucosal NK cells against viral respiratory infections in children undergoing haematopoietic stem cell transplantation. Sci Rep. 2019;9:18792 pubmed publisher
Oh E, Min B, Li Y, Lian C, Hong J, Park G, et al. Cryopreserved Human Natural Killer Cells Exhibit Potent Antitumor Efficacy against Orthotopic Pancreatic Cancer through Efficient Tumor-Homing and Cytolytic Ability (Running Title: Cryopreserved NK Cells Exhibit Antitumor Effect). Cancers (Basel). 2019;11: pubmed publisher
Streltsova M, Erokhina S, Kanevskiy L, Lee D, Telford W, Sapozhnikov A, et al. Analysis of NK cell clones obtained using interleukin-2 and gene-modified K562 cells revealed the ability of "senescent" NK cells to lose CD57 expression and start expressing NKG2A. PLoS ONE. 2018;13:e0208469 pubmed publisher
Han B, Mao F, Zhao Y, Lv Y, Teng Y, Duan M, et al. Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer. J Immunol Res. 2018;2018:6248590 pubmed publisher
Campbell T, McSharry B, Steain M, Ashhurst T, Slobedman B, Abendroth A. Varicella zoster virus productively infects human natural killer cells and manipulates phenotype. PLoS Pathog. 2018;14:e1006999 pubmed publisher
Nuñez S, Ziblat A, Secchiari F, Torres N, Sierra J, Raffo Iraolagoitia X, et al. Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-? and Engagement of CD85j. J Immunol. 2018;200:1008-1015 pubmed publisher
Shi J, Zhao J, Zhang X, Cheng Y, Hu J, Li Y, et al. Activated hepatic stellate cells impair NK cell anti-fibrosis capacity through a TGF-β-dependent emperipolesis in HBV cirrhotic patients. Sci Rep. 2017;7:44544 pubmed publisher
Collins A, Rothman N, Liu K, Reiner S. Eomesodermin and T-bet mark developmentally distinct human natural killer cells. JCI Insight. 2017;2:e90063 pubmed publisher
Guo C, Shen X, Fu B, Liu Y, Chen Y, Ni F, et al. CD3(bright)CD56(+) T cells associate with pegylated interferon-alpha treatment nonresponse in chronic hepatitis B patients. Sci Rep. 2016;6:25567 pubmed publisher
Viel S, Besson L, Charrier E, Marçais A, Disse E, Bienvenu J, et al. Alteration of Natural Killer cell phenotype and function in obese individuals. Clin Immunol. 2017;177:12-17 pubmed publisher
Picardi A, Mengarelli A, Marino M, Gallo E, Benevolo M, Pescarmona E, et al. Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts. J Exp Clin Cancer Res. 2015;34:98 pubmed publisher
Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, et al. NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure. PLoS ONE. 2015;10:e0134568 pubmed publisher
Spallanzani R, Torres N, Avila D, Ziblat A, Iraolagoitia X, Rossi L, et al. Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors. J Immunol. 2015;195:2141-8 pubmed publisher
Kruse V, Hamann C, Monecke S, Cyganek L, Elsner L, Hübscher D, et al. Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1. PLoS ONE. 2015;10:e0125544 pubmed publisher
Roberti M, Juliá E, Rocca Y, Amat M, Bravo A, Loza J, et al. Overexpression of CD85j in TNBC patients inhibits Cetuximab-mediated NK-cell ADCC but can be restored with CD85j functional blockade. Eur J Immunol. 2015;45:1560-9 pubmed publisher
Hu X, Jiang Y, Li X, Gao Y, Guo X, Chi X, et al. Long-term effect on natural killer cells by interferon-α therapy on the outcomes of HCV infection. J Interferon Cytokine Res. 2014;34:366-75 pubmed publisher
Qu J, Hou Z, Han Q, Jiang W, Zhang C, Tian Z, et al. Intracellular poly(I:C) initiated gastric adenocarcinoma cell apoptosis and subsequently ameliorated NK cell functions. J Interferon Cytokine Res. 2014;34:52-9 pubmed publisher
Zhao J, Li Y, Jin L, Zhang S, Fan R, Sun Y, et al. Natural killer cells are characterized by the concomitantly increased interferon-? and cytotoxicity in acute resolved hepatitis B patients. PLoS ONE. 2012;7:e49135 pubmed publisher
Clemente A, Cambra A, Munoz Saá I, Crespí C, Pallares L, Juan A, et al. Phenotype markers and cytokine intracellular production by CD8+ gammadelta T lymphocytes do not support a regulatory T profile in Behçet's disease patients and healthy controls. Immunol Lett. 2010;129:57-63 pubmed publisher
Ogbomo H, Michaelis M, Altenbrandt B, Doerr H, Cinatl J. A novel immunomodulatory mechanism of ribavirin in suppressing natural killer cell function. Biochem Pharmacol. 2010;79:188-97 pubmed publisher
Teixeira Carvalho A, Fujiwara R, Stemmy E, Olive D, Damsker J, Loukas A, et al. Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil. Infect Immun. 2008;76:5810-6 pubmed publisher
Cai L, Zhang Z, Zhou L, Wang H, Fu J, Zhang S, et al. Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients. Clin Immunol. 2008;129:428-37 pubmed publisher
Correale J, Villa A. Isolation and characterization of CD8+ regulatory T cells in multiple sclerosis. J Neuroimmunol. 2008;195:121-34 pubmed publisher
product information
brand :
R&D Systems
master code :
FAB1059P
SKU :
FAB1059P-025
product name :
Human NKG2A/CD159a PE-conjugated Antibody
description :
The Human NKG2A/CD159a PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to NKG2A/CD159a/KLRC1. This antibody reacts with human. The Human NKG2A/CD159a PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
NKG2A/CD159a/KLRC1
category :
Primary Antibodies
unit size :
25 Tests (also 100 Tests)
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
131411
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human NKG2A and CD94
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.
gene symbol :
KLRC1
catalog number base :
FAB1059P
applications :
Flow Cytometry
2020 USD :
129
2021 USD :
129 USD
alt names :
CD159 antigen-like family member A, CD159a, CD159a antigen, C-lectin type II protein, killer cell lectin-like receptor subfamily C, member 1, Klrc1, MGC13374, natural killer cell lectin, natural killer group protein 2, NK cell receptor A, NKG2, NKG2-1/B activating NK receptor, NKG2-A, NKG2-A/B type II integral membrane protein, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein, NKG2AMGC59791, NKG2-B
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.