Human NKG2A/CD159a APC-conjugated Antibody | R&D Systems FAB1059A-025 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NKG2A/CD159a APC-conjugated Antibody

catalog :

FAB1059A-025

quantity :

25 Tests (also 100 Tests)

price :

189 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

131411

reactivity :

human

application :

immunohistochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 13

Reference
Huuhtanen J, Kasanen H, Peltola K, L xf6 nnberg T, Glumoff V, Br xfc ck O, et al. Single-cell characterization of anti-LAG-3 and anti-PD-1 combination treatment in patients with melanoma. J Clin Invest. 2023;133: pubmed publisher
Fernandez R, Mayoral J, Pierre Louis L, Yao Y, Xu Y, Mu S, et al. Improving NK cell function in multiple myeloma with NKTR-255, a novel polymer-conjugated human IL-15. Blood Adv. 2023;7:9-19 pubmed publisher
Calabrese D, Aminian E, Mallavia B, Liu F, Cleary S, Aguilar O, et al. Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury. J Clin Invest. 2021;131: pubmed publisher
Zhu X, Qin X, Wang X, Wang Y, Cao W, Zhang J, et al. Oral cancer cell‑derived exosomes modulate natural killer cell activity by regulating the receptors on these cells. Int J Mol Med. 2020;46:2115-2125 pubmed publisher
Tseng H, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020;11:4810 pubmed publisher
Pump W, Kraemer T, Huyton T, Hò G, Blasczyk R, Bade Doeding C. Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8⁺ T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia. Int J Mol Sci. 2019;20: pubmed publisher
Gill U, Peppa D, Micco L, Singh H, Carey I, Foster G, et al. Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo. PLoS Pathog. 2016;12:e1005788 pubmed publisher
Chen Y, Chen B, Yang T, Xiao W, Qian L, Ding Y, et al. Human fused NKG2D-IL-15 protein controls xenografted human gastric cancer through the recruitment and activation of NK cells. Cell Mol Immunol. 2017;14:293-307 pubmed publisher
van Meijgaarden K, Haks M, Caccamo N, Dieli F, Ottenhoff T, Joosten S. Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset. PLoS Pathog. 2015;11:e1004671 pubmed publisher
Dupuy S, Lambert M, Zucman D, Choukem S, Tognarelli S, Pagès C, et al. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog. 2012;8:e1002486 pubmed publisher
Teixeira Carvalho A, Fujiwara R, Stemmy E, Olive D, Damsker J, Loukas A, et al. Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil. Infect Immun. 2008;76:5810-6 pubmed publisher
Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, et al. Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Blood. 2008;111:3155-62 pubmed publisher
Ballan W, Vu B, Long B, Loo C, Michaelsson J, Barbour J, et al. Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity. J Immunol. 2007;179:3362-70 pubmed

product information

brand :

R&D Systems

master code :

FAB1059A

SKU :

FAB1059A-025

product name :

Human NKG2A/CD159a APC-conjugated Antibody

unit size :

25 Tests (also 100 Tests)

seo description :

The Human NKG2A/CD159a APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to NKG2A/CD159a/KLRC1. This antibody reacts with human. The Human NKG2A/CD159a APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunohistochemistry.

target :

NKG2A/CD159a

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

131411

conjugate :

Allophycocyanin

dilution :

Flow Cytometry 10 uL/10^6 cells

host :

Mouse

immunogen :

BaF3 mouse pro-B cell line transfected with human NKG2A and CD94

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.

gene symbol :

KLRC1

top caption :

Detection of NKG2A/CD159a antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

applications :

Flow Cytometry,Immunohistochemistry,Neutralization

USD :

189 USD

alt names :

CD159 antigen-like family member A, CD159a, CD159a antigen, C-lectin type II protein, killer cell lectin-like receptor subfamily C, member 1, Klrc1, MGC13374, natural killer cell lectin, natural killer group protein 2, NK cell receptor A, NKG2, NKG2-1/B activating NK receptor, NKG2-A, NKG2-A/B type II integral membrane protein, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein, NKG2AMGC59791, NKG2-B

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage