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company name :
R&D Systems
product type :
other
product name :
Boc-QAR-AMC Fluorogenic Peptide Substrate
catalog :
ES014
quantity :
10 mg
price :
281 USD
more info or order :
citations: 15
Reference
Peng T, Wen J, Huang G, Zhao H, Liu J. First-generation high-affinity ST14 radiopharmaceutical: Design, synthesis, and preclinical PET imaging evaluation for pancreatic cancer detection. Bioorg Chem. 2025;154:108085 pubmed publisher
Strobelt R, Adler J, Shaul Y. The Transmembrane Protease Serine 2 (TMPRSS2) Non-Protease Domains Regulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike-Mediated Virus Entry. Viruses. 2023;15: pubmed publisher
Saunders N, Fernandez I, Planchais C, Michel V, Rajah M, Baquero Salazar E, et al. TMPRSS2 is a functional receptor for human coronavirus HKU1. Nature. 2023;624:207-214 pubmed publisher
Zhang Y, Sun S, Du C, Hu K, Zhang C, Liu M, et al. Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation. J Biol Chem. 2022;298:102643 pubmed publisher
Dion S, D xe9 silets A, Lemieux G, Leduc R. Functionally impaired isoforms regulate TMPRSS6 proteolytic activity. PLoS ONE. 2022;17:e0273825 pubmed publisher
Duru N, Pawar N, Martin E, Buzza M, Conway G, Lapidus R, et al. Selective targeting of metastatic ovarian cancer using an engineered anthrax prodrug activated by membrane-anchored serine proteases. Proc Natl Acad Sci U S A. 2022;119:e2201423119 pubmed publisher
Sure F, Bertog M, Afonso S, Diakov A, Rinke R, Madej M, et al. Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit. J Biol Chem. 2022;298:102004 pubmed publisher
Shapira T, Monreal I, Dion S, Buchholz D, Imbiakha B, Olmstead A, et al. A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic. Nature. 2022;605:340-348 pubmed publisher
Kwon H, Ha H, Jeon H, Jang J, Son S, Lee K, et al. Structure-activity relationship studies of dipeptide-based hepsin inhibitors with Arg bioisosteres. Bioorg Chem. 2021;107:104521 pubmed publisher
Azouz N, Klingler A, Callahan V, Akhrymuk I, Elez K, Raich L, et al. Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2. bioRxiv. 2020;: pubmed publisher
Reihill J, Ouyang X, Yang Z, Douglas L, Zhou M, Chen T, et al. A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction. Biomolecules. 2020;10: pubmed publisher
Kim K, Kwon H, Choi D, Lim T, Minn I, Son S, et al. Design and synthesis of dye-conjugated hepsin inhibitors. Bioorg Chem. 2019;89:102990 pubmed publisher
Dion S, Béliveau F, Morency L, Desilets A, Najmanovich R, Leduc R. Functional diversity of TMPRSS6 isoforms and variants expressed in hepatocellular carcinoma cell lines. Sci Rep. 2018;8:12562 pubmed publisher
Dion S, Béliveau F, Desilets A, Ghinet M, Leduc R. Transcriptome analysis reveals TMPRSS6 isoforms with distinct functionalities. J Cell Mol Med. 2018;22:2498-2509 pubmed publisher
Ferguson T, Reihill J, Walker B, Hamilton R, Martin S. A Selective Irreversible Inhibitor of Furin Does Not Prevent Pseudomonas Aeruginosa Exotoxin A-Induced Airway Epithelial Cytotoxicity. PLoS ONE. 2016;11:e0159868 pubmed publisher
product information
master code :
ES014
SKU :
ES014
product name :
Boc-QAR-AMC Fluorogenic Peptide Substrate
unit size :
10 mg
target :
Protease Substrates
category :
Activity Assays
species :
Multi-Species
source short :
Synthetic
extended description :
Substrate for Matriptase, Spinesin, and Prostasin
USD :
281 USD
product details :
Substrate for Matriptase, Spinesin, and Prostasin
storage :
Samples are stable for up to twelve months from date of receipt at -20░ C to -70░ C. The substrate can be aliquoted and stored -20░ C to -70░ C in a manual defrost freezer for three months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.