This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ITCH/AIP4 Isoform 2 Protein, CF
catalog :
E3-260
quantity :
100 ug
price :
275 USD
citations: 1
Reference
Chmura J, HEROLD K, Ruffin A, Atuobi T, Fabiyi Y, Mitchell A, et al. The Itch ubiquitin ligase is required for KSHV RTA induced vFLIP degradation. Virology. 2017;501:119-126 pubmed publisher
product information
brand :
R&D Systems, powered by Boston Biochem
master code :
E3-260
SKU :
E3-260-100
product name :
Recombinant Human ITCH/AIP4 Isoform 2 Protein, CF
description :
The Recombinant Human ITCH/AIP4 Isoform 2 Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human ITCH/AIP4 Isoform 2 Protein, CF has been validated for the following applications: Bioactivity.
target :
ITCH / AIP4
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
X mg/ml (X µM) in 50 mM HEPES pH 7.5, 150 mM NaCl, 10% Glycerol, 2 mM TCEP
conjugate :
Unconjugated
main entrez gene id :
83737
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain
species :
Human
theoretical molecular weight :
99 kDa
gene symbol :
ITCH
details of functionality :
Recombinant Human ITCH/AIP4 is a HECT domain Ubiquitin ligase (E3) that functions downstream of a Ubiquitin-activating (E1) enzyme and a Ubiquitin-conjugating (E2) enzyme to conjugate Ubiquitin to substrate proteins. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human ITCH/AIP4 concentration of 0.1-0.5 µM.
catalog number base :
E3-260
accessionNumbers :
Q96J02-2
applications :
Bioactivity
source :
The Recombinant Human ITCH / AIP4 Isoform 2 Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human ITCH / AIP4 Isoform 2 Protein, CF has been validated for the following applications: Bioactivity.
USD :
275 USD
alt names :
AIF4, AIP4, AIP4dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4)), atrophin-1 interacting protein 4, Atrophin-1-interacting protein 4, dJ468O1.1, EC 6.3.2, EC 6.3.2.-, Itch, itchy (mouse homolog) E3 ubiquitin protein ligase, itchy E3 ubiquitin protein ligase homolog (mouse), itchy homolog E3 ubiquitin protein ligase, NAPP1, NAPP1E3 ubiquitin-protein ligase Itchy homolog, NFE2-associated polypeptide 1, ubiquitin protein ligase ITCH
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.