Recombinant Human MDM2/HDM2 Protein, CF | R&D Systems E3-204 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human MDM2/HDM2 Protein, CF

catalog :

E3-204

quantity :

50 ug

price :

325 USD

citations: 2

Reference
Brydon E, Bronstein R, Buskin A, Lako M, Pierce E, Fernandez Godino R. AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/- iPSC-Derived RPE Cells. Mol Ther Methods Clin Dev. 2019;15:392-402 pubmed publisher
McClurg U, Cork D, Darby S, Ryan Munden C, Nakjang S, Mendes Côrtes L, et al. Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity. Nucleic Acids Res. 2017;45:1793-1804 pubmed publisher

product information

brand :

R&D Systems, powered by Boston Biochem

master code :

E3-204

SKU :

E3-204-050

product name :

Recombinant Human MDM2/HDM2 Protein, CF

description :

The Recombinant Human MDM2/HDM2 Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human MDM2/HDM2 Protein, CF has been validated for the following applications: Bioactivity.

target :

MDM2 / HDM2

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

X mg/ml (X µM) in 50 mM Hepes pH 8.0, 200 mM NaCl, 10% glycerol, 5 mM TCEP

conjugate :

Unconjugated

main entrez gene id :

4193

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.

species :

Human

theoretical molecular weight :

55 kDa

gene symbol :

MDM2

details of functionality :

Recombinant Human Mdm2/Hdm2 is a RING finger Ubiquitin ligase (E3) that functions downstream of a Ubiquitin-activating (E1) enzyme and a Ubiquitin-conjugating (E2) enzyme to conjugate Ubiquitin to substrate proteins. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human Mdm2/Hdm2 concentration of 0.5-5 µM.

catalog number base :

E3-204

accessionNumbers :

Q00987-1

applications :

Bioactivity

source :

The Recombinant Human MDM2 / HDM2 Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human MDM2 / HDM2 Protein, CF has been validated for the following applications: Bioactivity.

USD :

325 USD

alt names :

ACTFS, HDM2, HDMX, MDM2 oncogene, E3 ubiquitin protein ligase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.