Recombinant Human Parkin Protein, CF | R&D Systems E3-160-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Parkin Protein, CF

catalog :

E3-160-025

quantity :

25 ug

price :

541 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Ardah M, Radwan N, Khan E, Kitada T, Haque M. Parkin Precipitates on Mitochondria via Aggregation and Autoubiquitination. Int J Mol Sci. 2023;24: pubmed publisher
Roverato N, Sailer C, Catone N, Aichem A, Stengel F, Groettrup M. Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy. Cell Rep. 2021;34:108857 pubmed publisher

product information

brand :

R&D Systems

master code :

E3-160

SKU :

E3-160-025

product name :

Recombinant Human Parkin Protein, CF

unit size :

25 ug

seo description :

The Recombinant Human Parkin Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Parkin Protein, CF has been validated for the following applications: Bioactivity.

target :

Parkin

category :

Proteins and Enzymes

buffer :

Supplied as a solution in Tris, NaCl, Brij-35, TCEP and Glycerol.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.

species :

Human

theoretical molecular weight :

52 kDa

gene symbol :

PARK2

details of functionality :

Reaction conditions will need to be optimized for each specific application. As supplied, Parkin has negligible E3 ligase activity as determined by the lack of autoubiquitination in an in vitro assay. Parkin ligase activity is greatly enhanced by phosphorylation.

accessionNumbers :

O60260.2

applications :

Bioactivity

source :

Sf 21 (baculovirus)-derived Recombinant Human Parkin Protein, CF

USD :

541 USD

alt names :

AR-JP, E3 ubiquitin ligase, E3 ubiquitin-protein ligase parkin, EC 6.3.2.-, LPRS2, PARK2, parkin, parkin 2, Parkinson disease protein 2, Parkinson juvenile disease protein 2, parkinson protein 2, E3 ubiquitin protein ligase (parkin), PDJ, PDJjuvenile) 2, parkin, PRKN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage