Recombinant Human His6UBE2S Protein, CF | R&D Systems E2-690-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human His6UBE2S Protein, CF

catalog :

E2-690-100

quantity :

100 ug

more info or order :

R&D Systems product webpage

citations: 4

Reference
Khan O, Almagro J, Nelson J, Horswell S, Encheva V, Keyan K, et al. Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12. Nat Commun. 2021;12:2043 pubmed publisher
Li F, Yuan P, Rao M, Jin C, Tang W, Rong Y, et al. piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis. Nat Cell Biol. 2020;22:425-438 pubmed publisher
Fottner M, Brunner A, Bittl V, Horn Ghetko D, Jussupow A, Kaila V, et al. Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase. Nat Chem Biol. 2019;15:276-284 pubmed publisher
Zhou W, Xu J, Li H, Xu M, Chen Z, Wei W, et al. Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage. Clin Cancer Res. 2017;23:1104-1116 pubmed publisher

product information

master code :

E2-690

SKU :

E2-690-100

product name :

Recombinant Human His6UBE2S Protein, CF

unit size :

100 ug

description :

The Recombinant Human His6UBE2S Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human His6UBE2S Protein, CF has been validated for the following applications: Enzyme Activity.

target :

UBE2S

category :

Proteins and Enzymes

buffer :

Supplied as a solution in HEPES, NaCl, TCEP and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.

species :

Human

theoretical molecular weight :

26 kDa

gene symbol :

UBE2S

details of functionality :

Recombinant Human His6-UBE2S is a member of the Ubiquitin-conjugating (E2) enzyme family that receives Ubiquitin from a Ubiquitin-activating (E1) enzyme and subsequently interacts with a Ubiquitin ligase (E3) to conjugate Ubiquitin to substrate proteins. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human His6-UBE2S concentration of 0.1-1 ╡M.

accessionNumbers :

NP_055316.2

applications :

Enzyme Activity

source long :

E. coli -derived human UBE2S protein Met1 - Leu222 with a N-terminal 6-His tag

source short :

E. coli

extended description :

Will be discontinued when existing inventory is gone.

product details :

Will be discontinued when existing inventory is gone.

alt names :

E2-24K, E2-EPF, E2-EPF5, E2-EPF52, E2-EPFEC 6.3.2.19, E2EPFEPF5, EPF5, Ubiquitin carrier protein S, ubiquitin-conjugating enzyme E2 S, ubiquitin-conjugating enzyme E2-24 kD, Ubiquitin-conjugating enzyme E2-24 kDa, Ubiquitin-conjugating enzyme E2-EPF5, ubiquitin-conjugating enzyme E2S, Ubiquitin-protein ligase S

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage