Recombinant Human UbcH10/UBE2C Protein, CF | R&D Systems E2-654 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human UbcH10/UBE2C Protein, CF

catalog :

E2-654

quantity :

100 ug

price :

239 USD

citations: 4

Reference
Zheng L, Conner S. PI5P4K? functions in DTX1-mediated Notch signaling. Proc Natl Acad Sci U S A. 2018;115:E1983-E1990 pubmed publisher
Kagami Y, Ono M, Yoshida K. Plk1 phosphorylation of CAP-H2 triggers chromosome condensation by condensin II at the early phase of mitosis. Sci Rep. 2017;7:5583 pubmed publisher
Schnerch D, Schuler J, Follo M, Felthaus J, Wider D, Klingner K, et al. Proteasome inhibition enhances the efficacy of volasertib-induced mitotic arrest in AML in vitro and prolongs survival in vivo. Oncotarget. 2017;8:21153-21166 pubmed publisher
Zhou W, Xu J, Li H, Xu M, Chen Z, Wei W, et al. Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage. Clin Cancer Res. 2017;23:1104-1116 pubmed publisher

product information

brand :

R&D Systems, powered by Boston Biochem

master code :

E2-654

SKU :

E2-654-100

product name :

Recombinant Human UbcH10/UBE2C Protein, CF

description :

The Recombinant Human UbcH10/UBE2C Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human UbcH10/UBE2C Protein, CF has been validated for the following applications: Bioactivity.

target :

UbcH10 / UBE2C

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

0.50 mg/ml (25 µM) in 50 mM HEPES pH 7.0, 200 mM NaCl, 10% Gycerol (v/v), 1 mM TCEP

conjugate :

Unconjugated

main entrez gene id :

11065

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain

species :

Human

theoretical molecular weight :

20 kDa

gene symbol :

UBE2C

details of functionality :

Recombinant Human UbcH10/UBE2C is a member of the Ubiquitin-conjugating Enzyme (E2) family that receives Ubiquitin from a Ubiquitin-Activating Enzyme (E1) and subsequently interacts with a Ubiquitin ligase (E3) to conjugate ubiquitin to substrate proteins. Reaction conditions will need to be optimized for each specific application. We recommend an initial UbcH10/UBE2C concentration of 0.1--1 µM.

catalog number base :

E2-654

accessionNumbers :

O00762

applications :

Bioactivity

source :

The Recombinant Human UbcH10 / UBE2C Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human UbcH10 / UBE2C Protein, CF has been validated for the following applications: Bioactivity.

USD :

239 USD

alt names :

cyclin-selective ubiquitin carrier protein, dJ447F3.2, EC 6.3.2.19, UbcH10, UBCH10mitotic-specific ubiquitin-conjugating enzyme, UBE2C, Ubiquitin carrier protein C, ubiquitin carrier protein E2-C, ubiquitin-conjugating enzyme E2 C, ubiquitin-conjugating enzyme E2C, Ubiquitin-protein ligase C

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.