Recombinant Human His6-UBE2R1/CDC34 Protein, CF | R&D Systems E2-610 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human His6-UBE2R1/CDC34 Protein, CF

catalog :

E2-610

quantity :

100 ug

price :

239 USD

citations: 4

Reference
de Moura T, Mozaffari Jovin S, Szabó C, Schmitzová J, Dybkov O, Cretu C, et al. Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol Cell. 2018;69:979-992.e6 pubmed publisher
Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, et al. BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation. Nature. 2017;546:549-553 pubmed publisher
Kuang P, Tan M, Zhou W, Zhang Q, Sun Y. SAG/RBX2 E3 ligase complexes with UBCH10 and UBE2S E2s to ubiquitylate β-TrCP1 via K11-linkage for degradation. Sci Rep. 2016;6:37441 pubmed publisher
Wang J, Muntean A, Wu L, Hess J. A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity. J Biol Chem. 2012;287:43410-6 pubmed publisher

product information

brand :

R&D Systems, powered by Boston Biochem

master code :

E2-610

SKU :

E2-610-100

product name :

Recombinant Human His6-UBE2R1/CDC34 Protein, CF

description :

The Recombinant Human His6-UBE2R1/CDC34 Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human His6-UBE2R1/CDC34 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

UBE2R1 / CDC34

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

X mg/ml (µM) in 50 mM HEPES pH 7.5, 200 mM NaCl, 1 mM TCEP, 10% Glycerol (v/v)

conjugate :

Unconjugated

main entrez gene id :

997

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain

species :

Human

theoretical molecular weight :

28 kDa

gene symbol :

CDC34

details of functionality :

Recombinant Human His6-UbcH3/Cdc34 is a member of the Ubiquitin-conjugating (E2) enzyme family that receives Ubiquitin from a Ubiquitin-activating (E1) enzyme and subsequently interacts with a Ubiquitin ligase (E3) to conjugate Ubiquitin to substrate proteins. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human His6-UbcH3/Cdc34 concentration of 0.1-1 µM.

catalog number base :

E2-610

accessionNumbers :

P49427

applications :

Enzyme Activity

source :

The Recombinant Human His6-UBE2R1 / CDC34 Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human His6-UBE2R1 / CDC34 Protein, CF has been validated for the following applications: Enzyme Activity.

USD :

239 USD

alt names :

Cdc34, cell division cycle 34, cell division cycle 34 homolog (S. cerevisiae), E2-CDC34, EC 6.3.2.19, UBC3, UBE2R1UBCH3, ubiquitin carrier protein, ubiquitin-conjugating enzyme E2 R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, Ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.