Recombinant SARS-CoV-2 3CL Protease, CF | R&D Systems E-720-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant SARS-CoV-2 3CL Protease, CF

catalog :

E-720-050

quantity :

50 ug

price :

502 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Suresh V, Sheik D, Detomasi T, Zhao T, Zepeda T, Saladi S, et al. A Prototype Assay Multiplexing SARS-CoV-2 3CL-Protease and Angiotensin-Converting Enzyme 2 for Saliva-Based Diagnostics in COVID-19. Biosensors (Basel). 2023;13: pubmed publisher
Zhu K, Suskiewicz M, Hlou x161 ek Kasun A, Meudal H, Miko x10d A, Aucagne V, et al. DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates. Sci Adv. 2022;8:eadd4253 pubmed publisher

image

image 1 :

Recombinant SARS-CoV-2 3CL Protease Inhibition Activity

product information

master code :

E-720

SKU :

E-720-050

product name :

Recombinant SARS-CoV-2 3CL Protease, CF

unit size :

50 ug

description :

The Recombinant SARS-CoV-2 3CL Protease, CF from R&D Systems is derived from E. coli. The Recombinant SARS-CoV-2 3CL Protease, CF has been validated for the following applications: Bioactivity.

target :

3CL Protease

category :

Proteins and Enzymes

buffer :

Supplied as a solution in HEPES, NaCl, DTT and EDTA.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.

species :

SARS-CoV-2

theoretical molecular weight :

34 kDa

details of functionality :

Recombinant SARS-CoV-2 3CL Protease is a cysteine protease that cleaves proteins with sequences including LQ(S/A/G). The cleavage occurs c-terminal to the glutamine residue. Reaction conditions will need to be optimized for each specific application. We recommend an initial SARS-CoV-2 3CL Protease concentration of 20-40 nM when using substrate S-720 .

top caption :

Recombinant SARS-CoV-2 3CL Protease Inhibition Activity

accessionNumbers :

YP_009725301.1

applications :

Bioactivity

source long :

E. coli -derived sars-cov-2 3CL Protease protein Ser1 - Gln306

source short :

E. coli

extended description :

E. coli Expressed, Bioactivity Tested

USD :

502 USD

product details :

E. coli Expressed, Bioactivity Tested

alt names :

3CL Proteinase, 3C-like main protease, 3CL-Mpro, COVID-19, M Proteinase, Main Protease, Mpro

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage