product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant SARS-CoV-2 GST-Papain-like Protease, CF
catalog :
E-611-050
quantity :
50 ug
price :
502 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Mali S, Silva R, Gong Z, Cronce M, Vo U, Vuong C, et al. SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain. bioRxiv. 2024;: pubmed publisher
Węglarz Tomczak E, Tomczak J, Talma M, Burda Grabowska M, Giurg M, Brul S. Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2. Sci Rep. 2021;11:3640 pubmed publisher
image
image 1 :
R&D Systems E-611-050 image 1
Recombinant SARS-CoV-2 GST-Papain-like Protease SDS-PAGE
product information
master code :
E-611
SKU :
E-611-050
product name :
Recombinant SARS-CoV-2 GST-Papain-like Protease, CF
unit size :
50 ug
description :
The Recombinant SARS-CoV-2 GST-Papain-like Protease, CF from R&D Systems is derived from E. coli. The Recombinant SARS-CoV-2 GST-Papain-like Protease, CF has been validated for the following applications: Bioactivity.
target :
Papain-like Protease
category :
Proteins and Enzymes
buffer :
Supplied as a solution in HEPES, NaCl, Glycerol and TCEP.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.
species :
SARS-CoV-2
theoretical molecular weight :
62 kDa
details of functionality :
Recombinant SARS-CoV-2 virus Papain-like protease (PLPro) is a Ubiquitin- and ISG15-deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial PLPro concentration of 20-100 nM when using Ubiquitin-Rhodamine 110 (U-555) substrate. When using polyubiquitin chain substrate(s), this enzyme demonstrates a preference for K48 linkages.
top caption :
Recombinant SARS-CoV-2 GST-Papain-like Protease SDS-PAGE
accessionNumbers :
YP_009725299.1
applications :
Bioactivity
source long :
E. coli -derived sars-cov-2 Papain-like Protease protein Glu746 - Lys1060, with an N-terminal GST-tag
source short :
E. coli
extended description :
E. coli Expressed, Bioactivity Tested
USD :
502 USD
product details :
E. coli Expressed, Bioactivity Tested
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.