Recombinant Human His6-USP1/His6-UAF1 Complex Protein, CF | R&D Systems E-568-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human His6-USP1/His6-UAF1 Complex Protein, CF

catalog :

E-568-050

quantity :

50 ug

price :

569 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Tyagi A, Kaushal K, Chandrasekaran A, Sarodaya N, Das S, Park C, et al. CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells. Theranostics. 2022;12:5949-5970 pubmed publisher
Lawson A, Bak D, Shannon D, Long M, Vijaykumar T, Yu R, et al. Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry. Oncotarget. 2017;8:51296-51316 pubmed publisher
van Twest S, Murphy V, Hodson C, Tan W, Swuec P, O Rourke J, et al. Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway. Mol Cell. 2017;65:247-259 pubmed publisher
Lecona E, Rodriguez Acebes S, Specks J, López Contreras A, Ruppen I, Murga M, et al. USP7 is a SUMO deubiquitinase essential for DNA replication. Nat Struct Mol Biol. 2016;23:270-7 pubmed publisher

product information

master code :

E-568

SKU :

E-568-050

product name :

Recombinant Human His6-USP1/His6-UAF1 Complex Protein, CF

unit size :

50 ug

description :

The Recombinant Human His6-USP1/His6-UAF1 Complex Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human His6-USP1/His6-UAF1 Complex Protein, CF has been validated for the following applications: Bioactivity.

target :

USP1/UAF1 Complex

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in HEPES, NaCl, TCEP and Glycerol.

conjugate :

Unconjugated

species :

Human

theoretical molecular weight :

89 kDa (USP1), 77 kDa (UAF1)

gene symbol :

USP1

details of functionality :

Recombinant Human USP1/UAF1 complex is a Ubiquitin-specific deconjugating enzyme heterodimer. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human USP1/UAF1 complex concentration of 0.01-0.5 ╡M.

accessionNumbers :

O94782.1 (USP1), Q8TAF3.1 (UAF1)

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived human USP1/UAF1 Complex protein Met1 - Leu785 (Gly670Ala, Gly671Ala) with a C-terminal 6-His tag (USP1), Met1 - Thr677 with a C-terminal 6-His tag (UAF1)

source short :

Sf 21 (baculovirus)

USD :

569 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage