product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human His6-USP8 Protein, CF
catalog :
E-520-025
quantity :
25 ug
price :
400 USD
more info or order :
citations: 2
Reference
Papp S, Huber A, Jordan S, Kriebs A, Nguyen M, Moresco J, et al. DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. elife. 2015;4: pubmed publisher
Liang Q, Dexheimer T, Zhang P, Rosenthal A, Villamil M, You C, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014;10:298-304 pubmed publisher
product information
master code :
E-520
SKU :
E-520-025
product name :
Recombinant Human His6-USP8 Protein, CF
unit size :
25 ug
description :
The Recombinant Human His6-USP8 Protein, CF from R&D Systems is derived from Sf 9 (baculovirus). The Recombinant Human His6-USP8 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
USP8
category :
Proteins and Enzymes
buffer :
Supplied as a solution in HEPES, NaCl and TCEP.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.
species :
Human
theoretical molecular weight :
131 kDa
gene symbol :
USP8
details of functionality :
Recombinant Human His6-USP8 is a Ubiquitin-specific deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human His6-USP8 concentration of 10-50 nM.
accessionNumbers :
P40818.1
applications :
Enzyme Activity
source long :
Spodoptera frugiperda , Sf 9 (baculovirus)-derived human USP8 protein Met1 - Thr1118 (Pro2Gly, Val4Ala & V257Ala) with a N-terminal 6-His tag
source short :
Sf 9 (baculovirus)
USD :
400 USD
alt names :
Deubiquitinating enzyme 8, EC 3.1.2.15, EC 3.4.19.12, HumORF8, KIAA0055hUBPy, MGC129718, ubiquitin carboxyl-terminal hydrolase 8, Ubiquitin isopeptidase Y, ubiquitin specific peptidase 8, ubiquitin specific protease 8, ubiquitin thioesterase 8, Ubiquitin thiolesterase 8, Ubiquitin-specific-processing protease 8, UBPY, UBPYFLJ34456
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.