Recombinant Human His6-USP7 Protein, CF | R&D Systems E-519 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human His6-USP7 Protein, CF

catalog :

E-519

quantity :

25 ug

price :

269 USD

citations: 4

Reference
Gavory G, O Dowd C, Helm M, Flasz J, Arkoudis E, Dossang A, et al. Discovery and characterization of highly potent and selective allosteric USP7 inhibitors. Nat Chem Biol. 2017;: pubmed publisher
LandrÃ© V, Revi B, Mir M, Verma C, Hupp T, Gilbert N, et al. Regulation of transcriptional activators by DNA-binding domain ubiquitination. Cell Death Differ. 2017;24:903-916 pubmed publisher
Papp S, Huber A, Jordan S, Kriebs A, Nguyen M, Moresco J, et al. DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. elife. 2015;4: pubmed publisher
Liang Q, Dexheimer T, Zhang P, Rosenthal A, Villamil M, You C, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014;10:298-304 pubmed publisher

product information

brand :

R&D Systems, powered by Boston Biochem

master code :

E-519

SKU :

E-519-025

product name :

Recombinant Human His6-USP7 Protein, CF

description :

The Recombinant Human His6-USP7 Protein, CF from R&D Systems, powered by Boston Biochem is derived from Sf 21 (baculovirus). The Recombinant Human His6-USP7 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

USP7

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

X mg/ml (X µM) in 50 mM HEPES pH 7.5, 100 mM NaCl, 1 mM TCEP

conjugate :

Unconjugated

main entrez gene id :

7874

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain

species :

Human

theoretical molecular weight :

129 kDa

gene symbol :

USP7

details of functionality :

Recombinant Human His6-USP7 is a Ubiquitin-specific deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human His6-USP7 concentration of 1-5 nM.

catalog number base :

E-519

accessionNumbers :

Q93009

applications :

Enzyme Activity

source :

USD :

269 USD

alt names :

Deubiquitinating enzyme 7, EC 3.1.2.15, EC 3.4.19.12, HAUSP, HAUSPTEF1, Herpes virus-associated ubiquitin-specific protease, Herpesvirus-associated ubiquitin-specific protease, TEF1, ubiquitin carboxyl-terminal hydrolase 7, ubiquitin specific peptidase 7 (herpes virus-associated), ubiquitin specific protease 7 (herpes virus-associated), Ubiquitin thioesterase 7, Ubiquitin-specific-processing protease 7

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.