Reference |
---|
Davidson K, Bano M, Parker D, Osmulski P, Gaczynska M, Pickering A. β-Amyloid impairs Proteasome structure and function. Proteasome activation mitigates amyloid induced toxicity and cognitive deficits. bioRxiv. 2025;: pubmed publisher
|
Zimbone S, Romanucci V, Zarrelli A, Giuffrida M, Sciacca M, Lanza V, et al. Exploring the therapeutic potential of Aloin: unraveling neuroprotective and anticancer mechanisms, and strategies for enhanced stability and delivery. Sci Rep. 2024;14:16731 pubmed publisher
|
Wellington D, Yin Z, Yu Z, Heilig R, Davis S, Fischer R, et al. SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses. Heliyon. 2023;9:e20076 pubmed publisher
|
Tundo G, Sbardella D, Oddone F, Grasso G, Marini S, Atzori M, et al. Insulin-Degrading Enzyme Is a Non Proteasomal Target of Carfilzomib and Affects the 20S Proteasome Inhibition by the Drug. Biomolecules. 2022;12: pubmed publisher
|
Lee J, Pandey A, Venkatesh S, Thilagavathi J, Honda T, Singh K, et al. Inhibition of mitochondrial LonP1 protease by allosteric blockade of ATP binding and hydrolysis via CDDO and its derivatives. J Biol Chem. 2022;298:101719 pubmed publisher
|
Wang B, Zhu Y, Yu C, Zhang C, Tang Q, Huang H, et al. Hepatitis C virus induces oxidation and degradation of apolipoprotein B to enhance lipid accumulation and promote viral production. PLoS Pathog. 2021;17:e1009889 pubmed publisher
|
Guan H, Wang Y, Yu T, Huang Y, Li M, Saeed A, et al. Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures. PLoS Biol. 2020;18:e3000654 pubmed publisher
|
Yeo I, Lee M, Baek A, Miller Z, Bhattarai D, Baek Y, et al. A dual inhibitor of the proteasome catalytic subunits LMP2 and Y attenuates disease progression in mouse models of Alzheimer's disease. Sci Rep. 2019;9:18393 pubmed publisher
|
Scarpino A, Bajusz D, Proj M, Gobec M, Sosič I, Gobec S, et al. Discovery of Immunoproteasome Inhibitors Using Large-Scale Covalent Virtual Screening. Molecules. 2019;24: pubmed publisher
|
Li X, Huang Q, Long H, Zhang P, Su H, Liu J. A new gold(I) complex-Au(PPh3)PT is a deubiquitinase inhibitor and inhibits tumor growth. EBioMedicine. 2019;39:159-172 pubmed publisher
|
Wang Q, Gao X, Yu T, Yuan L, Dai J, Wang W, et al. REGγ Controls Hippo Signaling and Reciprocal NF-κB-YAP Regulation to Promote Colon Cancer. Clin Cancer Res. 2018;24:2015-2025 pubmed publisher
|
Bosc E, Nastri J, Lefort V, Valli M, Contiguiba F, Pioli R, et al. Piperlongumine and some of its analogs inhibit selectively the human immunoproteasome over the constitutive proteasome. Biochem Biophys Res Commun. 2018;496:961-966 pubmed publisher
|
Winter M, La Greca F, Arastu Kapur S, Caiazza F, Cimermancic P, Buchholz T, et al. Immunoproteasome functions explained by divergence in cleavage specificity and regulation. elife. 2017;6: pubmed publisher
|
Mikkonen E, Haglund C, Holmberg C. Immunohistochemical analysis reveals variations in proteasome tissue expression in C. elegans. PLoS ONE. 2017;12:e0183403 pubmed publisher
|
Chang A, Dao T, Gejman R, Jarvis C, Scott A, Dubrovsky L, et al. A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens. J Clin Invest. 2017;127:2705-2718 pubmed publisher
|
Zhou W, Wei L, Xiao T, Lai C, Peng M, Xu L, et al. Diabetogenic agent alloxan is a proteasome inhibitor. Biochem Biophys Res Commun. 2017;488:400-406 pubmed publisher
|
Palumbo R, Gogliettino M, Cocca E, Iannitti R, Sandomenico A, Ruvo M, et al. APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome. Int J Mol Sci. 2016;17: pubmed publisher
|
Santoro A, Monaco I, Attanasio F, Lanza V, Pappalardo G, Tomasello M, et al. Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study. Sci Rep. 2016;6:33444 pubmed publisher
|
Lee S, Levitsky K, Parlati F, Bennett M, Arastu Kapur S, Kellerman L, et al. Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: application of a novel pharmacodynamic assay. Br J Haematol. 2016;173:884-95 pubmed publisher
|
Li H, O Donoghue A, van der Linden W, Xie S, Yoo E, Foe I, et al. Structure- and function-based design of Plasmodium-selective proteasome inhibitors. Nature. 2016;530:233-6 pubmed publisher
|
Pundir S, Vu H, Solomon V, McClure R, Lee H. VR23: A Quinoline-Sulfonyl Hybrid Proteasome Inhibitor That Selectively Kills Cancer via Cyclin E-Mediated Centrosome Amplification. Cancer Res. 2015;75:4164-75 pubmed publisher
|
Akopian T, Kandror O, Tsu C, Lai J, Wu W, Liu Y, et al. Cleavage Specificity of Mycobacterium tuberculosis ClpP1P2 Protease and Identification of Novel Peptide Substrates and Boronate Inhibitors with Anti-bacterial Activity. J Biol Chem. 2015;290:11008-20 pubmed publisher
|
Maehama T, Kawahara K, Nishio M, Suzuki A, Hanada K. Nucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1 protein. J Biol Chem. 2014;289:20802-12 pubmed
|
Debowski D, Pikuła M, Lubos M, Langa P, Trzonkowski P, Lesner A, et al. Inhibition of human and yeast 20S proteasome by analogues of trypsin inhibitor SFTI-1. PLoS ONE. 2014;9:e89465 pubmed publisher
|
Nardon C, Schmitt S, Yang H, Zuo J, Fregona D, Dou Q. Gold(III)-dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy: preclinical studies against human breast neoplasia. PLoS ONE. 2014;9:e84248 pubmed publisher
|
Bergamo P, Cocca E, Palumbo R, Gogliettino M, Rossi M, Palmieri G. RedOx status, proteasome and APEH: insights into anticancer mechanisms of t10,c12-conjugated linoleic acid isomer on A375 melanoma cells. PLoS ONE. 2013;8:e80900 pubmed publisher
|
Henle A, Erskine C, Benson L, Clynes R, Knutson K. Enzymatic discovery of a HER-2/neu epitope that generates cross-reactive T cells. J Immunol. 2013;190:479-88 pubmed publisher
|
Gobec M, Obreza A, Prijatelj M, Brus B, Gobec S, Mlinaric Rascan I. Selective cytotoxicity of amidinopiperidine based compounds towards Burkitt's lymphoma cells involves proteasome inhibition. PLoS ONE. 2012;7:e41961 pubmed publisher
|