Recombinant Human UCH-L3 Protein, CF | R&D Systems E-325 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human UCH-L3 Protein, CF

catalog :

E-325

quantity :

25 ug

price :

125 USD

citations: 3

Reference
Su Z, Cao J, Wu Y, Chen W, Lin X, Wu Y, et al. Deubiquitylation of hepatitis B virus X protein (HBx) by ubiquitin-specific peptidase 15 (USP15) increases HBx stability and its transactivation activity. Sci Rep. 2017;7:40246 pubmed publisher
Shukla N, Somwar R, Smith R, Ambati S, Munoz S, Merchant M, et al. Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors. Cancer Res. 2016;76:4525-34 pubmed publisher
Liang Q, Dexheimer T, Zhang P, Rosenthal A, Villamil M, You C, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014;10:298-304 pubmed publisher

product information

brand :

R&D Systems, powered by Boston Biochem

master code :

E-325

SKU :

E-325-025

product name :

Recombinant Human UCH-L3 Protein, CF

description :

The Recombinant Human UCH-L3 Protein, CF from R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human UCH-L3 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

UCH-L3

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

X mg/ml (X µM) in 50 mM HEPES pH 7.5, 100 mM NaCl, 1 mM TCEP

conjugate :

Unconjugated

main entrez gene id :

7347

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain

species :

Human

theoretical molecular weight :

26 kDa

gene symbol :

UCHL3

details of functionality :

Recombinant Human UCH-L3 is a Ubiquitin-specific deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human UCH-L3 concentration of 0.05-5 nM. Pre-incubation for 15 minutes with 10 mM DTT is recommended to achieve maximum activity.

catalog number base :

E-325

accessionNumbers :

P15374

applications :

Enzyme Activity

source :

USD :

125 USD

alt names :

EC 3.4.19.12, ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L3, Ubiquitin thioesterase L3, ubiquitin thiolesterase, UCHL3, UCH-L3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.