| Reference |
|---|
Saavedra Sanchez L, Dickinson M, Apte S, Zhang Y, de Jong M, Skavicus S, et al. The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation. bioRxiv. 2024;: pubmed publisher |
Chan A, Haley R, Najar M, González Martínez D, Bugaj L, Burslem G, et al. Lipid-mediated intracellular delivery of recombinant bioPROTACs for the rapid degradation of undruggable proteins. Nat Commun. 2024;15:5808 pubmed publisher |
Wang J, Baddock H, Mafi A, Foe I, Bratkowski M, Lin T, et al. Structure of the p53 degradation complex from HPV16. Nat Commun. 2024;15:1842 pubmed publisher |
Zhu K, Suskiewicz M, Chatrin C, Str xf8 mland x, Dorsey B, Aucagne V, et al. DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on nucleic acids. Nucleic Acids Res. 2024;52:801-815 pubmed publisher |
Liu M, Wang Y, Teng F, Mai X, Wang X, Su M, et al. Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation. Nat Commun. 2023;14:7631 pubmed publisher |
Chuong P, Statsyuk A. Selective Smurf1 E3 ligase inhibitors that prevent transthiolation. bioRxiv. 2023;: pubmed publisher |
Liu S, Atkinson E, Paulucci Holthauzen A, Wang B. A CK2 and SUMO-dependent, PML NB-involved regulatory mechanism controlling BLM ubiquitination and G-quadruplex resolution. Nat Commun. 2023;14:6111 pubmed publisher |
Wu Z, Cao Z, Yao H, Yan X, Xu W, Zhang M, et al. Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2. Cell Rep. 2023;42:112693 pubmed publisher |
Zenko D, Marsh J, Castle A, Lewin R, Fischer R, Tofaris G. Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation. Sci Adv. 2023;9:eadd8910 pubmed publisher |
Ardah M, Radwan N, Khan E, Kitada T, Haque M. Parkin Precipitates on Mitochondria via Aggregation and Autoubiquitination. Int J Mol Sci. 2023;24: pubmed publisher |
Monda J, Ge X, Hunkeler M, Donovan K, Ma M, Jin C, et al. HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways. Cell Rep. 2023;42:112496 pubmed publisher |
Sharma J, Mulherkar S, Chen U, Xiong Y, Bajaj L, Cho B, et al. Calpain activity is negatively regulated by a KCTD7-Cullin-3 complex via non-degradative ubiquitination. Cell Discov. 2023;9:32 pubmed publisher |
Belmonte Fern xe1 ndez A, Herrero Ru xed z J, Galindo Moreno M, Lim xf3 n Mort xe9 s M, Mora Santos M, S xe1 ez C, et al. Cisplatin-induced cell death increases the degradation of the MRE11-RAD50-NBS1 complex through the autophagy/lysosomal pathway. Cell Death Differ. 2022;: pubmed publisher |
Zhu K, Suskiewicz M, Hlou x161 ek Kasun A, Meudal H, Miko x10d A, Aucagne V, et al. DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates. Sci Adv. 2022;8:eadd4253 pubmed publisher |
Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, et al. Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia. J Biol Chem. 2022;298:102314 pubmed publisher |
Ghilarducci K, Cabana V, Harake A, Cappadocia L, Lussier M. Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167. Int J Mol Sci. 2022;23: pubmed publisher |
Lee S, Garofano L, Ko A, D Angelo F, Frangaj B, Sommer D, et al. Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription. Nat Commun. 2022;13:2089 pubmed publisher |
Weston K, Gao X, Zhao J, Kim K, Maloney S, Gotoff J, et al. Identification of disease-linked hyperactivating mutations in UBE3A through large-scale functional variant analysis. Nat Commun. 2021;12:6809 pubmed publisher |
Mukhopadhyay C, Yang C, Xu L, Liu D, Wang Y, Huang D, et al. G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer. Nat Commun. 2021;12:6662 pubmed publisher |
Zhu Q, Huang J, Huang H, Li H, Yi P, Kloeber J, et al. RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination. Nat Commun. 2021;12:6653 pubmed publisher |
Fottner M, Weyh M, Gaussmann S, Schwarz D, Sattler M, Lang K. A modular toolbox to generate complex polymeric ubiquitin architectures using orthogonal sortase enzymes. Nat Commun. 2021;12:6515 pubmed publisher |
Harris L, Le Pen J, Scholz N, Mieszczanek J, Vaughan N, Davis S, et al. The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1. J Biol Chem. 2021;296:100246 pubmed publisher |
Wang S, Wang R, Peralta C, Yaseen A, Pavletich N. Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. Nat Struct Mol Biol. 2021;28:300-309 pubmed publisher |
Han M, Li J, Cao Y, Huang Y, Li W, Zhu H, et al. A role for LSH in facilitating DNA methylation by DNMT1 through enhancing UHRF1 chromatin association. Nucleic Acids Res. 2020;48:12116-12134 pubmed publisher |
Seo H, Kim H, Yoon J, Kweon T, Park Y, Kang J, et al. Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion. Cell Death Dis. 2020;11:815 pubmed publisher |
Deng M, Lin J, Nowsheen S, Liu T, Zhao Y, Villalta P, et al. Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents. Sci Adv. 2020;6: pubmed publisher |
Cathcart A, Bird G, Wales T, Herce H, Harvey E, Hauseman Z, et al. Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transfer. Nat Chem Biol. 2020;16:1218-1226 pubmed publisher |
Zhang F, Yan P, Yu H, Le H, Li Z, Chen J, et al. L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis. Cell Rep. 2020;32:107974 pubmed publisher |
Li F, Yuan P, Rao M, Jin C, Tang W, Rong Y, et al. piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis. Nat Cell Biol. 2020;22:425-438 pubmed publisher |
Li X, Guo M, Cai L, Du T, Liu Y, Ding H, et al. Competitive ubiquitination activates the tumor suppressor p53. Cell Death Differ. 2020;27:1807-1818 pubmed publisher |
Xie C, Tan M, Lin X, Wu D, Jiang Y, Tan Y, et al. The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling Pathways. Cell Rep. 2019;26:3037-3050.e4 pubmed publisher |
Fottner M, Brunner A, Bittl V, Horn Ghetko D, Jussupow A, Kaila V, et al. Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase. Nat Chem Biol. 2019;15:276-284 pubmed publisher |
Zhang L, Wang Z, Shi R, Zhu X, Zhou J, Peng B, et al. RNF126 Quenches RNF168 Function in the DNA Damage Response. Genomics Proteomics Bioinformatics. 2018;16:428-438 pubmed publisher |
Schneider T, Martinez Martinez A, Cubillos Rojas M, Bartrons R, Ventura F, Rosa J. The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation. Oncotarget. 2018;9:31531-31548 pubmed publisher |
Donovan K, An J, Nowak R, Yuan J, Fink E, Berry B, et al. Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome. elife. 2018;7: pubmed publisher |
Chen Y, Fokar M, Kang M, Chen N, Allen R, Chen Y. Phosphorylation of Arabidopsis SINA2 by CDKG1 affects its ubiquitin ligase activity. BMC Plant Biol. 2018;18:147 pubmed publisher |
Magliozzi R, Carrero Z, Low T, Yuniati L, Valdes Quezada C, Kruiswijk F, et al. Inheritance of the Golgi Apparatus and Cytokinesis Are Controlled by Degradation of GBF1. Cell Rep. 2018;23:3381-3391.e4 pubmed publisher |
Schuyler S, Wu Y, Chen H, Ding Y, Lin C, Chu Y, et al. Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison. PLoS ONE. 2018;13:e0198930 pubmed publisher |
Yao M, Zhou X, Zhou J, Gong S, Hu G, Li J, et al. PCGF5 is required for neural differentiation of embryonic stem cells. Nat Commun. 2018;9:1463 pubmed publisher |
Wojcik F, Dann G, Beh L, Debelouchina G, Hofmann R, Muir T. Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants. Nat Commun. 2018;9:1394 pubmed publisher |
de Moura T, Mozaffari Jovin S, Szabó C, Schmitzová J, Dybkov O, Cretu C, et al. Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol Cell. 2018;69:979-992.e6 pubmed publisher |
Tucker W, Kinghorn A, Fraser L, Cheung Y, Tanner J. Selection and Characterization of a DNA Aptamer Specifically Targeting Human HECT Ubiquitin Ligase WWP1. Int J Mol Sci. 2018;19: pubmed publisher |
Tsuchiya H, Burana D, Ohtake F, Arai N, Kaiho A, Komada M, et al. Ub-ProT reveals global length and composition of protein ubiquitylation in cells. Nat Commun. 2018;9:524 pubmed publisher |
Wang J, Grubb L, Wang J, Liang X, Li L, Gao C, et al. A Regulatory Module Controlling Homeostasis of a Plant Immune Kinase. Mol Cell. 2018;69:493-504.e6 pubmed publisher |
Guimarães D, Gomes M. Expression, purification, and characterization of the TRIM49 protein. Protein Expr Purif. 2018;143:57-61 pubmed publisher |
Yang C, Jividen K, Spencer A, Dworak N, Ni L, Oostdyk L, et al. Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9. Mol Cell. 2017;66:503-516.e5 pubmed publisher |
Paul A, Wang B. RNF8- and Ube2S-Dependent Ubiquitin Lysine 11-Linkage Modification in Response to DNA Damage. Mol Cell. 2017;66:458-472.e5 pubmed publisher |
Byrne R, Mund T, Licchesi J. Activity-Based Probes for HECT E3 Ubiquitin Ligases. Chembiochem. 2017;18:1415-1427 pubmed publisher |
Kuo C, Goldberg A. Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c. Proc Natl Acad Sci U S A. 2017;114:E3404-E3413 pubmed publisher |
Kliza K, Taumer C, Pinzuti I, Franz Wachtel M, Kunzelmann S, Stieglitz B, et al. Internally tagged ubiquitin: a tool to identify linear polyubiquitin-modified proteins by mass spectrometry. Nat Methods. 2017;14:504-512 pubmed publisher |
Tang M, Vranas M, Krahn A, Pundlik S, Trempe J, Fon E. Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation. Nat Commun. 2017;8:14697 pubmed publisher |
Harrison J, Cornett E, Goldfarb D, DaRosa P, Li Z, Yan F, et al. Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1. elife. 2016;5: pubmed publisher |
Du L, LI Y, Fakih M, Wiatrek R, Duldulao M, Chen Z, et al. Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal. Nat Commun. 2016;7:12326 pubmed publisher |
Itakura E, Zavodszky E, Shao S, Wohlever M, Keenan R, Hegde R. Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. Mol Cell. 2016;63:21-33 pubmed publisher |
Banh R, Iorio C, Marcotte R, Xu Y, Cojocari D, Rahman A, et al. PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia. Nat Cell Biol. 2016;18:803-813 pubmed publisher |
Sohn S, Hearing P. The adenovirus E4-ORF3 protein functions as a SUMO E3 ligase for TIF-1? sumoylation and poly-SUMO chain elongation. Proc Natl Acad Sci U S A. 2016;113:6725-30 pubmed publisher |
Lecona E, Rodriguez Acebes S, Specks J, López Contreras A, Ruppen I, Murga M, et al. USP7 is a SUMO deubiquitinase essential for DNA replication. Nat Struct Mol Biol. 2016;23:270-7 pubmed publisher |
Zhang Q, Karnak D, Tan M, Lawrence T, Morgan M, Sun Y. FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4. Mol Cell. 2016;61:419-433 pubmed publisher |
Wu L, Lee S, Zhou B, Nguyen U, Muir T, Tan S, et al. ASH2L regulates ubiquitylation signaling to MLL: trans-regulation of H3 K4 methylation in higher eukaryotes. Mol Cell. 2013;49:1108-20 pubmed publisher |
Clapp K, Peng H, Jenkins G, Ford M, Morishima Y, Lau M, et al. Ubiquitination of neuronal nitric-oxide synthase in the calmodulin-binding site triggers proteasomal degradation of the protein. J Biol Chem. 2012;287:42601-10 pubmed publisher |
Lu Y, Li J, Cheng D, Parameswaran B, Zhang S, Jiang Z, et al. The F-box protein FBXO44 mediates BRCA1 ubiquitination and degradation. J Biol Chem. 2012;287:41014-22 pubmed publisher |
Shibata Y, Oyama M, Kozuka Hata H, Han X, Tanaka Y, Gohda J, et al. p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO. Nat Commun. 2012;3:1061 pubmed publisher |
Janzer A, Stamm K, Becker A, Zimmer A, Buettner R, Kirfel J. The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine expression, cellular morphology, and the metabolome of fibroblasts. J Biol Chem. 2012;287:30984-92 pubmed publisher |
