product summary
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company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Total EGFR DuoSet IC ELISA
catalog :
DYC1854-2
quantity :
1 Kit (for 2 Plates) (also 1 Kit (for 5 Plates), 1 Pack (for 15 Plates))
price :
475 USD
more info or order :
citations: 9
Reference
Floc h N, Martin M, Riess J, Orme J, Staniszewska A, Ménard L, et al. Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions. Mol Cancer Ther. 2018;17:885-896 pubmed publisher
Scharadin T, He W, Yiannakou Y, Tomilov A, Saldana M, Cortopassi G, et al. Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system. PLoS ONE. 2017;12:e0177761 pubmed publisher
Jedlinski A, Garvin S, Johansson A, Edqvist P, Ponten F, Roberg K. Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc. J Oral Pathol Med. 2017;46:717-724 pubmed publisher
Bryan R, Regan H, Pirrie S, Devall A, Cheng K, Zeegers M, et al. Protein shedding in urothelial bladder cancer: prognostic implications of soluble urinary EGFR and EpCAM. Br J Cancer. 2015;112:1052-8 pubmed publisher
Kim S, Lewis C, Nadel J. Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme-dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H292) cells. Exp Cell Res. 2011;317:2650-60 pubmed publisher
Yamashita Kashima Y, Iijima S, Yorozu K, Furugaki K, Kurasawa M, Ohta M, et al. Pertuzumab in combination with trastuzumab shows significantly enhanced antitumor activity in HER2-positive human gastric cancer xenograft models. Clin Cancer Res. 2011;17:5060-70 pubmed publisher
O Brien N, Browne B, Chow L, Wang Y, Ginther C, Arboleda J, et al. Activated phosphoinositide 3-kinase/AKT signaling confers resistance to trastuzumab but not lapatinib. Mol Cancer Ther. 2010;9:1489-502 pubmed publisher
Hickinson D, Marshall G, Beran G, Varella Garcia M, Mills E, South M, et al. Identification of biomarkers in human head and neck tumor cell lines that predict for in vitro sensitivity to gefitinib. Clin Transl Sci. 2009;2:183-92 pubmed publisher
Shankaran H, Zhang Y, Opresko L, Resat H. Quantifying the effects of co-expressing EGFR and HER2 on HER activation and trafficking. Biochem Biophys Res Commun. 2008;371:220-4 pubmed publisher
image
image 1 :
R&D Systems DYC1854-2 image 1
product information
master code :
DYC1854-2
SKU :
DYC1854-2
product name :
Human Total EGFR DuoSet IC ELISA
unit size :
1 Kit (for 2 Plates) (also 1 Kit (for 5 Plates), 1 Pack (for 15 Plates))
description :
The Human Total EGFR DuoSet IC ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human EGFR.
target :
EGFR
category :
ELISAs
species :
Human
gene symbol :
EGFR
kit type :
Solid Phase Sandwich ELISA
assay length :
4 hours 40 mins (after plate preparation)
elisaRange :
31.20 - 2000 pg/mL
applications :
ELISA
USD :
475 USD
alt names :
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, EGF R, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ErbB, ErbB1, ERBB1PIG61, HER1, HER-1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.