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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human/Mouse/Rat Total HSP70/HSPA1A DuoSet IC ELISA
catalog :
DYC1663-2
quantity :
1 Kit (for 2 Plates) (also 1 Kit (for 5 Plates), 1 Pack (for 15 Plates))
price :
475 USD
citations: 25
Reference
Lennartz P, Th xf6 lke D, Bashiri Dezfouli A, Pilz M, Lobinger D, Messner V, et al. Biomarkers in Adult-Type Diffuse Gliomas: Elevated Levels of Circulating Vesicular Heat Shock Protein 70 Serve as a Biomarker in Grade 4 Glioblastoma and Increase NK Cell Frequencies in Grade 3 Glioma. Biomedicines. 2023;11: pubmed publisher
David O, Lategan K, de Cortalezzi M, Pool E. The Stability and Anti-Angiogenic Properties of Titanium Dioxide Nanoparticles (TiO2NPs) Using Caco-2 Cells. Biomolecules. 2022;12: pubmed publisher
Innamarato P, Morse J, Mackay A, Asby S, Beatty M, Blauvelt J, et al. Intralesional injection of rose bengal augments the efficacy of gemcitabine chemotherapy against pancreatic tumors. BMC Cancer. 2021;21:756 pubmed publisher
Playford R, Choudhry N, Kelly P, Marchbank T. Effects of Bovine Colostrum with or without Egg on In Vitro Bacterial-Induced Intestinal Damage with Relevance for SIBO and Infectious Diarrhea. Nutrients. 2021;13: pubmed publisher
Ratschker T, Egenberger L, Alev M, Zschiesche L, Band J, Schreiber E, et al. Mitoxantrone-Loaded Nanoparticles for Magnetically Controlled Tumor Therapy-Induction of Tumor Cell Death, Release of Danger Signals and Activation of Immune Cells. Pharmaceutics. 2020;12: pubmed publisher
Hader M, Savcigil D, Rosin A, Ponfick P, Gekle S, Wadepohl M, et al. Differences of the Immune Phenotype of Breast Cancer Cells after Ex Vivo Hyperthermia by Warm-Water or Microwave Radiation in a Closed-Loop System Alone or in Combination with Radiotherapy. Cancers (Basel). 2020;12: pubmed publisher
Theivanthiran B, Evans K, Devito N, Plebanek M, Sturdivant M, Wachsmuth L, et al. A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy. J Clin Invest. 2020;130:2570-2586 pubmed publisher
Kühnel A, Schilling D, Combs S, Haller B, Schwab M, Multhoff G. Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922. Cells. 2019;8: pubmed publisher
Haider T, Simader E, Glück O, Ankersmit H, Heinz T, Hajdu S, et al. Systemic release of heat-shock protein 27 and 70 following severe trauma. Sci Rep. 2019;9:9595 pubmed publisher
Nunes N, Chandran P, Sundby M, Visioli F, da Costa Gonçalves F, Burks S, et al. Therapeutic ultrasound attenuates DSS-induced colitis through the cholinergic anti-inflammatory pathway. EBioMedicine. 2019;45:495-510 pubmed publisher
Nam J, Son S, Ochyl L, Kuai R, Schwendeman A, Moon J. Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer. Nat Commun. 2018;9:1074 pubmed publisher
Dyer A, Di Y, Calderon H, Illingworth S, Kueberuwa G, Tedcastle A, et al. Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators. Mol Ther Oncolytics. 2017;4:18-30 pubmed publisher
Kovacs Z, Kim S, Jikaria N, Qureshi F, Milo B, Lewis B, et al. Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation. Proc Natl Acad Sci U S A. 2017;114:E75-E84 pubmed publisher
Shevchenko M, Troyanova N, Servuli E, Bolkhovitina E, Fedorina A, Sapozhnikov A. Study of Immunomodulatory Effects of Extracellular HSP70 in a Mouse Model of Allergic Airway Inflammation. Biochemistry (Mosc). 2016;81:1384-1395 pubmed
Kinzel L, Ernst A, Orth M, Albrecht V, Hennel R, Brix N, et al. A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer. Oncotarget. 2016;7:43199-43219 pubmed publisher
Lee C, Kokolus K, Leigh N, Capitano M, Hylander B, Repasky E. Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis. PLoS ONE. 2015;10:e0120327 pubmed publisher
Tulapurkar M, Ramarathnam A, Hasday J, Singh I. Bacterial lipopolysaccharide augments febrile-range hyperthermia-induced heat shock protein 70 expression and extracellular release in human THP1 cells. PLoS ONE. 2015;10:e0118010 pubmed publisher
Hillman N, Kemp M, Miura Y, Kallapur S, Jobe A. Sustained inflation at birth did not alter lung injury from mechanical ventilation in surfactant-treated fetal lambs. PLoS ONE. 2014;9:e113473 pubmed publisher
Roy A, Ganesh G, Sippola H, Bolin S, Sawesi O, Dagälv A, et al. Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation. J Biol Chem. 2014;289:237-50 pubmed publisher
Gupta A, Cooper Z, Tulapurkar M, Potla R, Maity T, Hasday J, et al. Toll-like receptor agonists and febrile range hyperthermia synergize to induce heat shock protein 70 expression and extracellular release. J Biol Chem. 2013;288:2756-66 pubmed publisher
Cwiklinska H, Mycko M, Szymanska B, Matysiak M, Selmaj K. Aberrant stress-induced Hsp70 expression in immune cells in multiple sclerosis. J Neurosci Res. 2010;88:3102-10 pubmed publisher
Kocsis J, Madaras B, Tóth E, Fust G, Prohaszka Z. Serum level of soluble 70-kD heat shock protein is associated with high mortality in patients with colorectal cancer without distant metastasis. Cell Stress Chaperones. 2010;15:143-51 pubmed publisher
Zhou F, Xing D, Chen W. Regulation of HSP70 on activating macrophages using PDT-induced apoptotic cells. Int J Cancer. 2009;125:1380-9 pubmed publisher
Figueiredo C, Wittmann M, Wang D, Dressel R, Seltsam A, Blasczyk R, et al. Heat shock protein 70 (HSP70) induces cytotoxicity of T-helper cells. Blood. 2009;113:3008-16 pubmed publisher
Li C, Ning W, Matthay M, Feghali Bostwick C, Choi A. MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production. Am J Physiol Lung Cell Mol Physiol. 2007;292:L1297-303 pubmed
product information
master code :
DYC1663-2
SKU :
DYC1663-2
product name :
Human/Mouse/Rat Total HSP70/HSPA1A DuoSet IC ELISA
unit size :
1 Kit (for 2 Plates) (also 1 Kit (for 5 Plates), 1 Pack (for 15 Plates))
description :
The Human/Mouse/Rat Total HSP70/HSPA1A DuoSet IC ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human, mouse, rat HSP70/HSPA1A.
target :
HSP70/HSPA1A
category :
ELISAs
species :
Human, Mouse, Rat
gene symbol :
HSPA1A
kit type :
Solid Phase Sandwich ELISA
assay length :
4 hours 40 mins (after plate preparation)
elisaRange :
156.00 - 10000 pg/mL
applications :
ELISA
USD :
475 USD
alt names :
dnaK-type molecular chaperone HSP70-1, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, Heat shock 70 kDa protein 1/2, heat shock 70 kDa protein 1A/1B, heat shock 70kD protein 1A, heat shock 70kDa protein 1A, heat shock-induced protein, HSP70.1/HSP70.2, HSP70-1, HSP70-1/HSP70-2, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.