This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) DuoSet IC ELISA
catalog :
DYC1018B-2
quantity :
1 Kit (for 2 Plates) (also 1 Kit (for 5 Plates), 1 Pack (for 15 Plates))
price :
475 USD
citations: 34
Reference
Feng S, Sanford J, Weber T, Hutchinson Bunch C, Dakup P, Paurus V, et al. A Phosphoproteomics Data Resource for Systems-level Modeling of Kinase Signaling Networks. bioRxiv. 2023;: pubmed publisher
Feigelman G, Simanovich E, Brockmeyer P, Rahat M. Knocking-Down CD147/EMMPRIN Expression in CT26 Colon Carcinoma Forces the Cells into Cellular and Angiogenic Dormancy That Can Be Reversed by Interactions with Macrophages. Biomedicines. 2023;11: pubmed publisher
Sakamoto K, Lin B, Nunomura K, Izawa T, Nakagawa S. The K-Ras(G12D)-inhibitory peptide KS-58 suppresses growth of murine CT26 colorectal cancer cell-derived tumors. Sci Rep. 2022;12:8121 pubmed publisher
Jung Y, Son M, Nam Y, Choi J, Heath J, Yang S. Microfluidic Single-Cell Proteomics Assay Chip: Lung Cancer Cell Line Case Study. Micromachines (Basel). 2021;12: pubmed publisher
De Zutter A, Crijns H, Berghmans N, García Caballero M, Vanbrabant L, Pörtner N, et al. The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors. Cancers (Basel). 2021;13: pubmed publisher
Sakamoto K, Masutani T, Hirokawa T. Generation of KS-58 as the first K-Ras(G12D)-inhibitory peptide presenting anti-cancer activity in vivo. Sci Rep. 2020;10:21671 pubmed publisher
Olsen D, Thomsen C, Andersen R, Madsen J, Jakobsen A, Brandslund I. Decreased concentrations of intracellular signaling proteins in colon cancer patients with BRAF mutations. Sci Rep. 2020;10:20113 pubmed publisher
Schepetkin I, Kirpotina L, Khlebnikov A, Balasubramanian N, Quinn M. Neutrophil Immunomodulatory Activity of Natural Organosulfur Compounds. Molecules. 2019;24: pubmed publisher
Khlebnikov A, Schepetkin I, Kishkentaeva A, Shaimerdenova Z, Atazhanova G, Adekenov S, et al. Inhibition of T Cell Receptor Activation by Semi-Synthetic Sesquiterpene Lactone Derivatives and Molecular Modeling of Their Interaction with Glutathione and Tyrosine Kinase ZAP-70. Molecules. 2019;24: pubmed publisher
Bhattacharyya S, Feferman L, Sharma G, Tobacman J. Increased GPNMB, phospho-ERK1/2, and MMP-9 in cystic fibrosis in association with reduced arylsulfatase B. Mol Genet Metab. 2018;124:168-175 pubmed publisher
Marcus Samuels B, Krieger C, Boutin A, Kahaly G, Neumann S, Gershengorn M. Evidence that Graves' Ophthalmopathy Immunoglobulins Do Not Directly Activate IGF-1 Receptors. Thyroid. 2018;: pubmed publisher
Kang H, Ku S, Kim J, Chung J, Kim S, Zhou W, et al. Anti-vascular inflammatory effects of pentacyclic triterpenoids from Astilbe rivularis in vitro and in vivo. Chem Biol Interact. 2017;261:127-138 pubmed publisher
Girkin J, Hatchwell L, Collison A, Starkey M, Hansbro P, Yagita H, et al. TRAIL signaling is proinflammatory and proviral in a murine model of rhinovirus 1B infection. Am J Physiol Lung Cell Mol Physiol. 2017;312:L89-L99 pubmed publisher
Eigenmann M, Frances N, Hoffmann G, Lavé T, Walz A. Combining Nonclinical Experiments with Translational PKPD Modeling to Differentiate Erlotinib and Gefitinib. Mol Cancer Ther. 2016;15:3110-3119 pubmed
Janssens R, Mortier A, Boff D, Vanheule V, Gouwy M, Franck C, et al. Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo. Oncotarget. 2016;7:62439-62459 pubmed publisher
Clancy P, Koblar S, Golledge J. Angiotensin receptor 1 blockade reduces secretion of inflammation associated cytokines from cultured human carotid atheroma and vascular cells in association with reduced extracellular signal regulated kinase expression and activation. Atherosclerosis. 2014;236:108-15 pubmed publisher
Knoop K, McDonald K, McCrate S, McDole J, Newberry R. Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon. Mucosal Immunol. 2015;8:198-210 pubmed publisher
Ghezali L, Liagre B, Limami Y, Beneytout J, Leger D. Sonic Hedgehog activation is implicated in diosgenin-induced megakaryocytic differentiation of human erythroleukemia cells. PLoS ONE. 2014;9:e95016 pubmed publisher
Summers L, Kangwantas K, Rodriguez Grande B, Denes A, Penny J, Kielty C, et al. Activation of brain endothelial cells by interleukin-1 is regulated by the extracellular matrix after acute brain injury. Mol Cell Neurosci. 2013;57:93-103 pubmed publisher
Ghezali L, Leger D, Limami Y, Cook Moreau J, Beneytout J, Liagre B. Cyclopamine and jervine induce COX-2 overexpression in human erythroleukemia cells but only cyclopamine has a pro-apoptotic effect. Exp Cell Res. 2013;319:1043-53 pubmed publisher
Vernitsky H, Rechavi O, Rainy N, Besser M, Nagar M, Schachter J, et al. Ras oncoproteins transfer from melanoma cells to T cells and modulate their effector functions. J Immunol. 2012;189:4361-70 pubmed publisher
Gouwy M, Struyf S, Berghmans N, Vanormelingen C, Schols D, Van Damme J. CXCR4 and CCR5 ligands cooperate in monocyte and lymphocyte migration and in inhibition of dual-tropic (R5/X4) HIV-1 infection. Eur J Immunol. 2011;41:963-73 pubmed publisher
Chen J, Olivares Navarrete R, Wang Y, Herman T, Boyan B, Schwartz Z. Protein-disulfide isomerase-associated 3 (Pdia3) mediates the membrane response to 1,25-dihydroxyvitamin D3 in osteoblasts. J Biol Chem. 2010;285:37041-50 pubmed publisher
Lorquet S, Berndt S, Blacher S, Gengoux E, Peulen O, Maquoi E, et al. Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment. FASEB J. 2010;24:3782-95 pubmed publisher
Yeh C, Li H, Malhotra D, Turcato S, Nicholas S, Tu R, et al. Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse. J Cell Biochem. 2010;109:1185-91 pubmed publisher
Wang S, Zhou Q, Gallo J. Demonstration of the equivalent pharmacokinetic/pharmacodynamic dosing strategy in a multiple-dose study of gefitinib. Mol Cancer Ther. 2009;8:1438-47 pubmed publisher
Struyf S, Noppen S, Loos T, Mortier A, Gouwy M, Verbeke H, et al. Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4. J Immunol. 2009;182:666-74 pubmed
Loos T, Mortier A, Gouwy M, Ronsse I, Put W, Lenaerts J, et al. Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation. Blood. 2008;112:2648-56 pubmed publisher
Gouwy M, Struyf S, Noppen S, Schutyser E, Springael J, Parmentier M, et al. Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events. Mol Pharmacol. 2008;74:485-95 pubmed publisher
Aguila B, Coulbault L, Boulouard M, Leveille F, Davis A, Toth G, et al. In vitro and in vivo pharmacological profile of UFP-512, a novel selective delta-opioid receptor agonist; correlations between desensitization and tolerance. Br J Pharmacol. 2007;152:1312-24 pubmed
Muselet Charlier C, Roque T, Boncoeur E, Chadelat K, Clement A, Jacquot J, et al. Enhanced IL-1beta-induced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NF-kappaB signaling. Biochem Biophys Res Commun. 2007;357:402-7 pubmed
Leger D, Liagre B, Beneytout J. Low dose leflunomide activates PI3K/Akt signalling in erythroleukemia cells and reduces apoptosis induced by anticancer agents. Apoptosis. 2006;11:1747-60 pubmed
Gee K, Angel J, Ma W, Mishra S, Gajanayaka N, Parato K, et al. Intracellular HIV-Tat expression induces IL-10 synthesis by the CREB-1 transcription factor through Ser133 phosphorylation and its regulation by the ERK1/2 MAPK in human monocytic cells. J Biol Chem. 2006;281:31647-58 pubmed
Vergne Salle P, Leger D, Bertin P, Treves R, Beneytout J, Liagre B. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes. Cytokine. 2005;31:335-48 pubmed
product information
master code :
DYC1018B-2
SKU :
DYC1018B-2
product name :
Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) DuoSet IC ELISA
unit size :
1 Kit (for 2 Plates) (also 1 Kit (for 5 Plates), 1 Pack (for 15 Plates))
description :
The Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) DuoSet IC ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies phosphorylated human, mouse, rat ERK1/ERK2.
target :
ERK1/ERK2
category :
ELISAs
species :
Human, Mouse, Rat
kit type :
Solid Phase Sandwich ELISA
elisaRange :
469.00 - 30000 pg/mL
applications :
ELISA
USD :
475 USD
alt names :
ERK1, ERK-1, ERT1, ERT2, Extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, HS44KDAP, HUMKER1A, Insulin-stimulated MAP2 kinase, MAPK 1, MAPK1, MAPK2, MAPK3, Microtubule-associated protein 2 kinase, mitogen-activated protein kinase 3, p41mapk, p42mapk, p44erk1, p44-ERK1, p44mapk, p44-MAPK, PRKM1, PRKM2, PRKM3
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.