This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Amphiregulin DuoSet ELISA
catalog :
DY262
quantity :
1 Kit (for 15 Plates)
price :
850 USD
citations: 42
Reference
Heires A, Samuelson D, Villageliu D, Nordgren T, Romberger D. Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA. Sci Rep. 2023;13:2767 pubmed publisher
Jaeger B, Schupp J, Plappert L, Terwolbeck O, Artysh N, Kayser G, et al. Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis. Nat Commun. 2022;13:5637 pubmed publisher
Patankar M, Li M, Khalatbari A, Castle J, Hu L, Zhang C, et al. Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts. Int J Mol Sci. 2022;23: pubmed publisher
Villar J, Herrán Monge R, Gonzalez Higueras E, Prieto González M, Ambrós A, Rodríguez Pérez A, et al. Clinical and biological markers for predicting ARDS and outcome in septic patients. Sci Rep. 2021;11:22702 pubmed publisher
Ghosh S, Nataraj N, Noronha A, Patkar S, Sekar A, Mukherjee S, et al. PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR. Cell Rep. 2021;35:109181 pubmed publisher
Lindzen M, Ghosh S, Noronha A, Drago D, Nataraj N, Leitner O, et al. Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53. Oncogene. 2021;40:3665-3679 pubmed publisher
Schiffers C, van de Wetering C, Bauer R, Habibovic A, Hristova M, Dustin C, et al. Downregulation of epithelial DUOX1 in chronic obstructive pulmonary disease. JCI Insight. 2021;6: pubmed publisher
Wang S, Li R, Ng T, Luthria G, Oudin M, Prytyskach M, et al. Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy. Sci Adv. 2020;6:eaaz8521 pubmed publisher
Ko J, Kim H, Jeong H, Lee H, Oh J. Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis. Cell Rep. 2020;30:3806-3820.e6 pubmed publisher
Sampera A, Sánchez Martín F, Arpi O, Visa L, Iglesias M, Menendez S, et al. HER-Family Ligands Promote Acquired Resistance to Trastuzumab in Gastric Cancer. Mol Cancer Ther. 2019;18:2135-2145 pubmed publisher
Ho J, Yang X, Nikou S, Kichik N, Donkin A, Ponde N, et al. Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor. Nat Commun. 2019;10:2297 pubmed publisher
Lam A, MacDonald K, Pesenacker A, Juvet S, Morishita K, Bressler B, et al. Innate Control of Tissue-Reparative Human Regulatory T Cells. J Immunol. 2019;202:2195-2209 pubmed publisher
Kubli S, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, et al. AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. Proc Natl Acad Sci U S A. 2019;116:3604-3613 pubmed publisher
Schmidt S, Schumacher N, Schwarz J, Tangermann S, Kenner L, Schlederer M, et al. ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling. J Exp Med. 2018;215:1205-1225 pubmed publisher
Nordgren T, BAILEY K, Heires A, Katafiasz D, Romberger D. Effects of Agricultural Organic Dusts on Human Lung-Resident Mesenchymal Stem (Stromal) Cell Function. Toxicol Sci. 2018;162:635-644 pubmed publisher
Haghgoo S, Khosravi A, Mortaz E, Pourabdollah Toutkaboni M, Seifi S, Sabour S, et al. Prognostic value of rare and complex mutations in EGFR and serum levels of soluble EGFR and its ligands in non-small cell lung carcinoma patients. Clin Biochem. 2017;50:293-300 pubmed publisher
Gao J, Ulekleiv C, Halstensen T. Epidermal growth factor (EGF) receptor-ligand based molecular staging predicts prognosis in head and neck squamous cell carcinoma partly due to deregulated EGF- induced amphiregulin expression. J Exp Clin Cancer Res. 2016;35:151 pubmed
Kefaloyianni E, Muthu M, Kaeppler J, Sun X, Sabbisetti V, Chalaris A, et al. ADAM17 substrate release in proximal tubule drives kidney fibrosis. JCI Insight. 2016;1: pubmed publisher
Breshears L, Gillman A, Stach C, Schlievert P, Peterson M. Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome. PLoS ONE. 2016;11:e0158969 pubmed publisher
Aderhold C, Faber A, Umbreit C, Birk R, Weiss C, Sommer J, et al. Targeting mTOR and AREG with everolimus, sunitinib and sorafenib in HPV-positive and -negative SCC. Anticancer Res. 2015;35:1951-9 pubmed
Noguchi S, Saito A, Horie M, Mikami Y, Suzuki H, Morishita Y, et al. An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer. Clin Cancer Res. 2014;20:4660-72 pubmed publisher
Parnia S, Hamilton L, Puddicombe S, Holgate S, Frew A, Davies D. Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles. Respir Res. 2014;15:22 pubmed publisher
Chen Z, Chen J, Gu Y, Hu C, Li J, Lin S, et al. Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells. Oncogene. 2014;33:3869-77 pubmed publisher
Tanizaki J, Okamoto I, Okabe T, Sakai K, Tanaka K, Hayashi H, et al. Activation of HER family signaling as a mechanism of acquired resistance to ALK inhibitors in EML4-ALK-positive non-small cell lung cancer. Clin Cancer Res. 2012;18:6219-26 pubmed publisher
Breshears L, Schlievert P, Peterson M. A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1). J Biol Chem. 2012;287:32578-87 pubmed
Richards F, Tape C, Jodrell D, Murphy G. Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo. PLoS ONE. 2012;7:e40597 pubmed publisher
Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev I, et al. The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. Clin Cancer Res. 2011;17:3619-30 pubmed publisher
Hickinson D, Marshall G, Beran G, Varella Garcia M, Mills E, South M, et al. Identification of biomarkers in human head and neck tumor cell lines that predict for in vitro sensitivity to gefitinib. Clin Transl Sci. 2009;2:183-92 pubmed publisher
Stoll S, Johnson J, Li Y, Rittie L, Elder J. Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growth. J Invest Dermatol. 2010;130:2031-40 pubmed publisher
Egloff A, Rothstein M, Seethala R, Siegfried J, Grandis J, Stabile L. Cross-talk between estrogen receptor and epidermal growth factor receptor in head and neck squamous cell carcinoma. Clin Cancer Res. 2009;15:6529-40 pubmed publisher
Han S, Oh D, Im S, Park S, Lee K, Song H, et al. Phase II study and biomarker analysis of cetuximab combined with modified FOLFOX6 in advanced gastric cancer. Br J Cancer. 2009;100:298-304 pubmed publisher
Inoue Y, Miyamoto S, Fukami T, Shirota K, Yotsumoto F, Kawarabayashi T. Amphiregulin is much more abundantly expressed than transforming growth factor-alpha and epidermal growth factor in human follicular fluid obtained from patients undergoing in vitro fertilization-embryo transfer. Fertil Steril. 2009;91:1035-41 pubmed publisher
Yotsumoto F, Yagi H, Suzuki S, Oki E, Tsujioka H, Hachisuga T, et al. Validation of HB-EGF and amphiregulin as targets for human cancer therapy. Biochem Biophys Res Commun. 2008;365:555-61 pubmed
Eckstein N, Servan K, Girard L, Cai D, von Jonquieres G, Jaehde U, et al. Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells. J Biol Chem. 2008;283:739-50 pubmed
Moss M, Bomar M, Liu Q, Sage H, Dempsey P, Lenhart P, et al. The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events. J Biol Chem. 2007;282:35712-21 pubmed
Rumelhard M, Ramgolam K, Hamel R, Marano F, Baeza Squiban A. Expression and role of EGFR ligands induced in airway cells by PM2.5 and its components. Eur Respir J. 2007;30:1064-73 pubmed
Lemos González Y, Rodriguez Berrocal F, Cordero O, Gomez C, Paez de la Cadena M. Alteration of the serum levels of the epidermal growth factor receptor and its ligands in patients with non-small cell lung cancer and head and neck carcinoma. Br J Cancer. 2007;96:1569-78 pubmed
Zhou B, Peyton M, He B, Liu C, Girard L, Caudler E, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 2006;10:39-50 pubmed
Janes K, Gaudet S, Albeck J, Nielsen U, Lauffenburger D, Sorger P. The response of human epithelial cells to TNF involves an inducible autocrine cascade. Cell. 2006;124:1225-39 pubmed
Baginski T, Dabbagh K, Satjawatcharaphong C, Swinney D. Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli. Am J Respir Cell Mol Biol. 2006;35:165-74 pubmed
Miyamoto S, Hirata M, Yamazaki A, Kageyama T, Hasuwa H, Mizushima H, et al. Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy. Cancer Res. 2004;64:5720-7 pubmed
Kansra S, Stoll S, Johnson J, Elder J. Autocrine extracellular signal-regulated kinase (ERK) activation in normal human keratinocytes: metalloproteinase-mediated release of amphiregulin triggers signaling from ErbB1 to ERK. Mol Biol Cell. 2004;15:4299-309 pubmed
product information
master code :
DY262
SKU :
DY262
product name :
Human Amphiregulin DuoSet ELISA
unit size :
1 Kit (for 15 Plates)
description :
The Human Amphiregulin DuoSet ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Amphiregulin.
target :
Amphiregulin
category :
ELISAs
species :
Human
gene symbol :
AREG
kit type :
Solid Phase Sandwich ELISA
elisaRange :
15.60 - 1000 pg/mL
top caption :
Human Amphiregulin ELISA Standard Curve
applications :
ELISA
USD :
850 USD
alt names :
amphiregulin, AR, AREG, AREGB, Colorectum cell-derived growth factor, CRDGF, MGC13647, schwannoma-derived growth factor, SDGF
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.