This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human IL-27 DuoSet ELISA
catalog :
DY2526-05
quantity :
1 Kit (for 5 Plates) (also 1 Kit (for 15 Plates))
price :
440 USD
citations: 36
Reference
Zhu H, Niu Y, Wen J, Yan C, Cha S, Gao Y, et al. Accuracy of interleukin-27 in diagnosing tuberculous pleural effusion: Age should be considered. Cytokine. 2025;186:156844 pubmed publisher
Pourfarzam S, Ardestani S, Jamali T, Ghazanfari H, Naghizadeh M, Faghihzadeh S, et al. Distinct inflammatory profiles in mustard lung: A study of sulfur mustard-exposed patients with serious pulmonary complications. Int Immunopharmacol. 2025;146:113832 pubmed publisher
Martin E, Winter S, Garcin C, Tanita K, Hoshino A, Lenoir C, et al. Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency. Nature. 2024;628:620-629 pubmed publisher
Pons S, Trouillet Assant S, Subtil F, Abbas Chorfa F, Cornaton E, Berthiot A, et al. Performance of 11 Host Biomarkers Alone or in Combination in the Diagnosis of Late-Onset Sepsis in Hospitalized Neonates: The Prospective EMERAUDE Study. Biomedicines. 2023;11: pubmed publisher
Peng Y, Guo S, Yan X, Zhang L, Wang J, Yuan G, et al. Collective outbreak of severe acute histoplasmosis in immunocompetent Chinese in South America: the clinical characteristics and continuous monitoring of serum cytokines/chemokines. BMC Prim Care. 2022;23:197 pubmed publisher
Zhou W, Yang H, Mei J, Chang K, Lu H, Lai Z, et al. Fructose-1,6-bisphosphate prevents pregnancy loss by inducing decidual COX-2+ macrophage differentiation. Sci Adv. 2022;8:eabj2488 pubmed publisher
Qi Y, Liu C, Zhong X, Ma X, Zhou J, Shi Y, et al. IL-27 as a potential biomarker for distinguishing between necrotising enterocolitis and highly suspected early-onset food protein-induced enterocolitis syndrome with abdominal gas signs. EBioMedicine. 2021;72:103607 pubmed publisher
Jover E, Matilla L, Garaikoetxea M, Fernández Celis A, Muntendam P, Jaisser F, et al. Beneficial Effects of Mineralocorticoid Receptor Pathway Blockade against Endothelial Inflammation Induced by SARS-CoV-2 Spike Protein. Biomedicines. 2021;9: pubmed publisher
Yendo T, Sato M, Branco A, Pietrobon A, Teixeira F, Ramos Y, et al. Impact of Inflammatory Immune Dysfunction in Psoriasis Patients at Risk for COVID-19. Vaccines (Basel). 2021;9: pubmed publisher
Min B, Kim D, Feige M. IL-30† (IL-27A): a familiar stranger in immunity, inflammation, and cancer. Exp Mol Med. 2021;53:823-834 pubmed publisher
Dalil Roofchayee N, Marjani M, Dezfuli N, Tabarsi P, Moniri A, Varahram M, et al. Potential diagnostic value of pleural fluid cytokines levels for tuberculous pleural effusion. Sci Rep. 2021;11:660 pubmed publisher
Jeon J, Lee Y, Yu H, Ha U. HSP70-Homolog DnaK of Pseudomonas aeruginosa Increases the Production of IL-27 through Expression of EBI3 via TLR4-Dependent NF-κB and TLR4-Independent Akt Signaling. Int J Mol Sci. 2020;21: pubmed publisher
Bobhate A, Viswanathan V, Aravindhan V. Anti-inflammatory cytokines IL-27, IL-10, IL-1Ra and TGF-β in subjects with increasing grades of glucose intolerence (DM-LTB-2). Cytokine. 2021;137:155333 pubmed publisher
Genaro L, Coser L, Justo Júnior A, de Castro L, Barreto A, Rizzato A, et al. Association between IL-27 and Tr1 cells in severe form of paracoccidioidomycosis. Cytokine. 2020;127:154962 pubmed publisher
Moideen K, Kumar N, Bethunaickan R, Banurekha V, Nair D, Babu S. Heightened systemic levels of anti-inflammatory cytokines in pulmonary tuberculosis and alterations following anti-tuberculosis treatment. Cytokine. 2020;127:154929 pubmed publisher
Ma M, Percopo C, Sturdevant D, Sek A, Komarow H, Rosenberg H. Cytokine Diversity in Human Peripheral Blood Eosinophils: Profound Variability of IL-16. J Immunol. 2019;: pubmed publisher
Zhang L, Zhang J, Su S, Luo S. Changes in interleukin-27 levels in patients with acute coronary syndrome and their clinical significance. Peerj. 2019;7:e5652 pubmed publisher
Loughran S, Power P, Maguire P, McQuaid S, Buchanan P, Jonsdottir I, et al. Influenza infection directly alters innate IL-23 and IL-12p70 and subsequent IL-17A and IFN-γ responses to pneumococcus in vitro in human monocytes. PLoS ONE. 2018;13:e0203521 pubmed publisher
Busca A, Konarski Y, Gajanayaka N, O Hara S, Angel J, Kozlowski M, et al. cIAP1/2-TRAF2-SHP-1-Src-MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-κB Activation in Human Macrophages. J Immunol. 2018;200:1593-1606 pubmed publisher
Nuñez S, Ziblat A, Secchiari F, Torres N, Sierra J, Raffo Iraolagoitia X, et al. Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-? and Engagement of CD85j. J Immunol. 2018;200:1008-1015 pubmed publisher
Golic N, Veljovic K, Popovic N, Djokic J, Strahinic I, Mrvaljević I, et al. In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens. BMC Microbiol. 2017;17:108 pubmed publisher
Garg A, Trout R, Spector S. Human Immunodeficiency Virus Type-1 Myeloid Derived Suppressor Cells Inhibit Cytomegalovirus Inflammation through Interleukin-27 and B7-H4. Sci Rep. 2017;7:44485 pubmed publisher
Hojo Souza N, Pereira D, de Souza F, de Oliveira Mendes T, Cardoso M, Tada M, et al. On the cytokine/chemokine network during Plasmodium vivax malaria: new insights to understand the disease. Malar J. 2017;16:42 pubmed publisher
Zhang Z, Zhou B, Zhang K, Song Y, Zhang L, Xi M. IL-27 suppresses SKOV3 cells proliferation by enhancing STAT3 and inhibiting the Akt signal pathway. Mol Immunol. 2016;78:155-163 pubmed publisher
Malecka A, Wang Q, Shah S, Sutavani R, Spendlove I, Ramage J, et al. Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation. J Leukoc Biol. 2016;100:381-9 pubmed publisher
Teles R, Kelly Scumpia K, Sarno E, Rea T, Ochoa M, Cheng G, et al. IL-27 Suppresses Antimicrobial Activity in Human Leprosy. J Invest Dermatol. 2015;135:2410-2417 pubmed publisher
Guha R, Das S, Ghosh J, Sundar S, Dujardin J, Roy S. Antimony resistant Leishmania donovani but not sensitive ones drives greater frequency of potent T-regulatory cells upon interaction with human PBMCs: role of IL-10 and TGF-β in early immune response. PLoS Negl Trop Dis. 2014;8:e2995 pubmed publisher
Dietrich C, Candon S, Ruemmele F, Devergne O. A soluble form of IL-27R? is a natural IL-27 antagonist. J Immunol. 2014;192:5382-9 pubmed publisher
Zhang X, Tao Y, Chopra M, Ahn M, Marcus K, Choudhary N, et al. Differential reconstitution of T cell subsets following immunodepleting treatment with alemtuzumab (anti-CD52 monoclonal antibody) in patients with relapsing-remitting multiple sclerosis. J Immunol. 2013;191:5867-74 pubmed publisher
Lechner C, Komander K, Hegewald J, Huang X, Gantin R, Soboslay P, et al. Cytokine and chemokine responses to helminth and protozoan parasites and to fungus and mite allergens in neonates, children, adults, and the elderly. Immun Ageing. 2013;10:29 pubmed publisher
Fitzgerald D, Fonseca Kelly Z, Cullimore M, Safabakhsh P, Saris C, Zhang G, et al. Independent and interdependent immunoregulatory effects of IL-27, IFN-?, and IL-10 in the suppression of human Th17 cells and murine experimental autoimmune encephalomyelitis. J Immunol. 2013;190:3225-34 pubmed publisher
Jiang S, Liu X, Luo L, Qu B, Huang X, Lin Y, et al. Serum levels of Th17-related cytokines in Behcet disease patients after cataract surgery. Mol Vis. 2011;17:1425-30 pubmed
Sweeney C, Lonergan R, Basdeo S, Kinsella K, Dungan L, Higgins S, et al. IL-27 mediates the response to IFN-? therapy in multiple sclerosis patients by inhibiting Th17 cells. Brain Behav Immun. 2011;25:1170-81 pubmed publisher
Ramgolam V, Sha Y, Marcus K, Choudhary N, Troiani L, Chopra M, et al. B cells as a therapeutic target for IFN-? in relapsing-remitting multiple sclerosis. J Immunol. 2011;186:4518-26 pubmed publisher
Guzzo C, Hopman W, Che Mat N, Wobeser W, Gee K. Impact of HIV infection, highly active antiretroviral therapy, and hepatitis C coinfection on serum interleukin-27. AIDS. 2010;24:1371-4 pubmed publisher
Correale J, Farez M. Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms. J Immunol. 2009;183:5999-6012 pubmed publisher
product information
master code :
DY2526
SKU :
DY2526-05
product name :
Human IL-27 DuoSet ELISA
unit size :
1 Kit (for 5 Plates) (also 1 Kit (for 15 Plates))
description :
The Human IL-27 DuoSet ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human IL-27.
target :
IL-27
category :
ELISAs
species :
Human
gene symbol :
IL27
kit type :
Solid Phase Sandwich ELISA
elisaRange :
156.00 - 10000 pg/mL
top caption :
Human IL-27 ELISA Standard Curve
applications :
ELISA
USD :
440 USD
alt names :
IL27, IL-27, IL-27 p28 subunit, IL-27 subunit alpha, IL27A, IL-27-A, IL27-A, IL27p28, IL30, interleukin 27, interleukin 30, interleukin-27 subunit alpha, MGC71873, p28IL-27A
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.