product summary
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company name :
R&D Systems
product type :
ELISA/assay
product name :
Human sgp130 DuoSet ELISA
catalog :
DY228
quantity :
1 Kit (for 15 Plates)
price :
850 USD
more info or order :
citations: 10
Reference
Rodr xed guez Hern xe1 ndez M, Baena Bustos M, Carneros D, Zurita Palomo C, Mu xf1 oz Pinillos P, Mill xe1 n J, et al. Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2 -infected mice and reduces endotheliopathy. EBioMedicine. 2024;103:105132 pubmed publisher
Westermann L, Baranowsky A, Di Lorenzo G, Danyukova T, Soul J, Schwartz J, et al. Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice. Sci Rep. 2021;11:3556 pubmed publisher
Escrig A, Molinero A, Méndez B, Giralt M, Comes G, Sanchis P, et al. IL-6 Trans-Signaling in the Brain Influences the Metabolic Phenotype of the 3xTg-AD Mouse Model of Alzheimer's Disease. Cells. 2020;9: pubmed publisher
Gupta S, Junquera G, Nicassio L, Becknell B, Ching C. Trans IL-6 signaling does not appear to play a role in renal scarring after urinary tract infection. J Pediatr Urol. 2020;16:586-591 pubmed publisher
McGregor N, Murat M, Elango J, Poulton I, Walker E, Crimeen Irwin B, et al. IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis. J Biol Chem. 2019;294:7850-7863 pubmed publisher
Broch K, Askevold E, Gjertsen E, Ueland T, Yndestad A, Godang K, et al. The effect of rosuvastatin on inflammation, matrix turnover and left ventricular remodeling in dilated cardiomyopathy: a randomized, controlled trial. PLoS ONE. 2014;9:e89732 pubmed publisher
Zhao S, Gu Y, Dong Q, Fan R, Wang Y. Altered interleukin-6 receptor, IL-6R and gp130, production and expression and decreased SOCS-3 expression in placentas from women with pre-eclampsia. Placenta. 2008;29:1024-8 pubmed publisher
Simon D, Denniston A, Tomlins P, Wallace G, Rauz S, Salmon M, et al. Soluble gp130, an antagonist of IL-6 transsignaling, is elevated in uveitis aqueous humor. Invest Ophthalmol Vis Sci. 2008;49:3988-91 pubmed publisher
Hsu H, Wittemann S, Schneider E, Weiss M, Joos T. Suspension microarrays for the identification of the response patterns in hyperinflammatory diseases. Med Eng Phys. 2008;30:976-83 pubmed publisher
Rabe B, Chalaris A, May U, Waetzig G, Seegert D, Williams A, et al. Transgenic blockade of interleukin 6 transsignaling abrogates inflammation. Blood. 2008;111:1021-8 pubmed
image
image 1 :
R&D Systems DY228 image 1
Human gp130 ELISA Standard Curve
product information
master code :
DY228
SKU :
DY228
product name :
Human sgp130 DuoSet ELISA
unit size :
1 Kit (for 15 Plates)
description :
The Human sgp130 DuoSet ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human gp130/CD130.
target :
gp130
category :
ELISAs
species :
Human
gene symbol :
IL6ST
kit type :
Solid Phase Sandwich ELISA
elisaRange :
156.00 - 10000 pg/mL
top caption :
Human gp130 ELISA Standard Curve
applications :
ELISA
USD :
850 USD
alt names :
CD130, CD130 antigen, CDw130, DKFZp564F053, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.