Ribeiro R, Silva E, Moreira F, Gomes G, Cussat G, Silva B, et al. Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling. Sci Rep. 2023;13:16358 pubmed publisher

Ford M, George B, Van Laar V, Holleran K, Naidoo J, Hadaczek P, et al. GDNF gene therapy for alcohol use disorder in male non-human primates. Nat Med. 2023;29:2030-2040 pubmed publisher

Novosadova E, Dolotov O, Novosadova L, Davydova L, Sidoruk K, Arsenyeva E, et al. Composite Coatings Based on Recombinant Spidroins and Peptides with Motifs of the Extracellular Matrix Proteins Enhance Neuronal Differentiation of Neural Precursor Cells Derived from Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2023;24: pubmed publisher

Escobar A, Carvalho M, Maia F, Reis R, Silva T, Oliveira J. Glial Cell Line-Derived Neurotrophic Factor-Loaded CMCht/PAMAM Dendrimer Nanoparticles for Peripheral Nerve Repair. Pharmaceutics. 2022;14: pubmed publisher

Baloh R, Johnson J, Avalos P, Allred P, Svendsen S, Gowing G, et al. Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial. Nat Med. 2022;28:1813-1822 pubmed publisher

Szpakowski P, Ksiazek Winiarek D, Turniak Kusy M, Pacan I, Glabinski A. Human Primary Astrocytes Differently Respond to Pro- and Anti-Inflammatory Stimuli. Biomedicines. 2022;10: pubmed publisher

Khaleel B, Lunenfeld E, Kapelushnik J, Huleihel M. Effect of Chemotherapy Cytarabine and Acute Myeloid Leukemia on the Development of Spermatogenesis at the Adult Age of Immature Treated Mice. Int J Mol Sci. 2022;23: pubmed publisher

Islamov R, Bashirov F, Izmailov A, Fadeev F, Markosyan V, Sokolov M, et al. New Therapy for Spinal Cord Injury: Autologous Genetically-Enriched Leucoconcentrate Integrated with Epidural Electrical Stimulation. Cells. 2022;11: pubmed publisher

Lee H, Yeum C, Lee H, Oh J, Kim J, Lee W, et al. Peripheral Nerve-Derived Stem Cell Spheroids Induce Functional Recovery and Repair after Spinal Cord Injury in Rodents. Int J Mol Sci. 2021;22: pubmed publisher

von Kanel R, Hamer M, Wentzel A, Malan L. Circulating neurotrophins and hemostatic risk factors of atherothrombotic cardiovascular disease at baseline and during sympathetic challenge: the SABPA study. Sci Rep. 2021;11:2297 pubmed publisher

Chenlo M, Rodriguez Gomez I, Serramito R, Garcia Rendueles A, Villar Taibo R, Fernandez Rodriguez E, et al. Unmasking a new prognostic marker and therapeutic target from the GDNF-RET/PIT1/p14ARF/p53 pathway in acromegaly. EBioMedicine. 2019;43:537-552 pubmed publisher

Paolone G, Falcicchia C, Lovisari F, Kokaia M, Bell W, Fradet T, et al. Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy. J Neurosci. 2019;39:2144-2156 pubmed publisher

Chu C, Chu C, Wu C, Lu T. Serum nerve growth factor beta, brain- and glial-derived neurotrophic factor levels and psychopathology in unmedicated patients with schizophrenia. J Chin Med Assoc. 2018;81:577-581 pubmed publisher

Gothelf Y, Kaspi H, Abramov N, Aricha R. miRNA profiling of NurOwn®: mesenchymal stem cells secreting neurotrophic factors. Stem Cell Res Ther. 2017;8:249 pubmed publisher

Stefani M, Modkovski R, Hansel G, Zimmer E, Kopczynski A, Muller A, et al. Elevated glutamate and lactate predict brain death after severe head trauma. Ann Clin Transl Neurol. 2017;4:392-402 pubmed publisher

Baranov P, Lin H, McCabe K, Gale D, Cai S, Lieppman B, et al. A Novel Neuroprotective Small Molecule for Glial Cell Derived Neurotrophic Factor Induction and Photoreceptor Rescue. J Ocul Pharmacol Ther. 2017;33:412-422 pubmed publisher

Li Z, Li X, Chan M, Wu W, Tan D, Shen J. Melatonin antagonizes interleukin-18-mediated inhibition on neural stem cell proliferation and differentiation. J Cell Mol Med. 2017;21:2163-2171 pubmed publisher

Thomsen G, Alkaslasi M, Vit J, Lawless G, Godoy M, Gowing G, et al. Systemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse side effects. Gene Ther. 2017;24:245-252 pubmed publisher

Cordeiro C, Vieira E, Rocha N, Castro V, Oréfice J, Barichello T, et al. Serum levels of neurotrophic factors in active toxoplasmic retinochoroiditis. Braz J Infect Dis. 2017;21:176-179 pubmed publisher

Zhu L, Su Q, Jie X, Liu A, Wang H, He B, et al. NG2 expression in microglial cells affects the expression of neurotrophic and proinflammatory factors by regulating FAK phosphorylation. Sci Rep. 2016;6:27983 pubmed publisher

Yurek D, Hasselrot U, Cass W, Sesenoglu Laird O, Padegimas L, Cooper M. Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles. Neuroscience. 2015;284:500-12 pubmed publisher

Kim K, Lee H, An J, Kim Y, Ra J, Lim I, et al. Transplantation of human adipose tissue-derived stem cells delays clinical onset and prolongs life span in ALS mouse model. Cell Transplant. 2014;23:1585-97 pubmed publisher

Zhang L, Li K, Liu X, Li D, Luo C, Fu B, et al. Repeated systemic administration of human adipose-derived stem cells attenuates overt diabetic nephropathy in rats. Stem Cells Dev. 2013;22:3074-86 pubmed publisher

Ohshima Hosoyama S, Simmons H, Goecks N, Joers V, Swanson C, Bondarenko V, et al. A monoclonal antibody-GDNF fusion protein is not neuroprotective and is associated with proliferative pancreatic lesions in parkinsonian monkeys. PLoS ONE. 2012;7:e39036 pubmed publisher

Touchard E, Heiduschka P, Berdugo M, Kowalczuk L, Bigey P, Chahory S, et al. Non-viral gene therapy for GDNF production in RCS rat: the crucial role of the plasmid dose. Gene Ther. 2012;19:886-98 pubmed publisher

Jones J, Anderson J, Phuah C, Fox E, Selmaj K, Margolin D, et al. Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity. Brain. 2010;133:2232-47 pubmed publisher

Glavaski Joksimovic A, Virag T, Mangatu T, McGrogan M, Wang X, Bohn M. Glial cell line-derived neurotrophic factor-secreting genetically modified human bone marrow-derived mesenchymal stem cells promote recovery in a rat model of Parkinson's disease. J Neurosci Res. 2010;88:2669-81 pubmed publisher

Han Y, Chang Q, Virag T, West N, George D, Castro M, et al. Lack of humoral immune response to the tetracycline (Tet) activator in rats injected intracranially with Tet-off rAAV vectors. Gene Ther. 2010;17:616-25 pubmed publisher

Hadaczek P, Johnston L, Forsayeth J, Bankiewicz K. Pharmacokinetics and bioactivity of glial cell line-derived factor (GDNF) and neurturin (NTN) infused into the rat brain. Neuropharmacology. 2010;58:1114-21 pubmed publisher

Emborg M, Moirano J, Raschke J, Bondarenko V, Zufferey R, Peng S, et al. Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Neurobiol Dis. 2009;36:303-11 pubmed publisher

Mertens B, Massie A, Michotte Y, Sarre S. Effect of nigrostriatal damage induced by 6-hydroxydopamine on the expression of glial cell line-derived neurotrophic factor in the striatum of the rat. Neuroscience. 2009;162:148-54 pubmed publisher

Suzuki M, McHugh J, Tork C, Shelley B, Hayes A, Bellantuono I, et al. Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS. Mol Ther. 2008;16:2002-10 pubmed publisher

Wang Y, Wu Y, Huang H, Lin H, Lo L, Tzeng S, et al. Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury. Biomaterials. 2008;29:4546-53 pubmed publisher

Sajadi A, Bensadoun J, Schneider B, Lo Bianco C, Aebischer P. Transient striatal delivery of GDNF via encapsulated cells leads to sustained behavioral improvement in a bilateral model of Parkinson disease. Neurobiol Dis. 2006;22:119-29 pubmed

Caggiula M, Batocchi A, Frisullo G, Angelucci F, Patanella A, Sancricca C, et al. Neurotrophic factors in relapsing remitting and secondary progressive multiple sclerosis patients during interferon beta therapy. Clin Immunol. 2006;118:77-82 pubmed

Puskovic V, Wolfe D, Goss J, Huang S, Mata M, Glorioso J, et al. Prolonged biologically active transgene expression driven by HSV LAP2 in brain in vivo. Mol Ther. 2004;10:67-75 pubmed

Yu G, Xu L, Hadman M, Hess D, Borlongan C. Intracerebral transplantation of carotid body in rats with transient middle cerebral artery occlusion. Brain Res. 2004;1015:50-6 pubmed

Truckenmiller M, Vawter M, Zhang P, Conejero Goldberg C, Dillon Carter O, Morales N, et al. AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression. Exp Neurol. 2002;175:318-37 pubmed

Bensadoun J, Deglon N, Tseng J, Ridet J, Zurn A, Aebischer P. Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF. Exp Neurol. 2000;164:15-24 pubmed