Pascual Pasto G, McIntyre B, Hines M, Giudice A, Garcia Gerique L, Hoffmann J, et al. CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma. Nat Commun. 2024;15:7141 pubmed publisher

da Costa Teixeira L, Soares L, Lima L, Avelar N, de Moura J, Leopoldino A, et al. Cognitive function is associated with performance in time up and go test and with leptin blood levels in community-dwelling older women. Sci Rep. 2024;14:9841 pubmed publisher

Augusto da Costa Teixeira L, Rocha Vieira E, Aparecida Soares L, Mota de Oliveira F, Aparecida Oliveira Leopoldino A, Netto Parentoni A, et al. The strong inverse association between plasma concentrations of soluble tumor necrosis factor receptors type 1 with adiponectin/leptin ratio in older women. Cytokine. 2024;176:156512 pubmed publisher

Manna L, Rapuano Lembo R, Yoshioka A, Nakamura K, Passariello M, De Lorenzo C. A Comparison of the Antitumor Efficacy of Novel Multi-Specific Tribodies with Combinations of Approved Immunomodulatory Antibodies. Cancers (Basel). 2023;15: pubmed publisher

Zobel C, Wenzel W, Kr xfc ger J, Baumgarten U, Wagel xf6 hner T, Neumann N, et al. Serum interleukin-6, procalcitonin, and C-reactive protein at hospital admission can identify patients at low risk for severe COVID-19 progression. Front Microbiol. 2023;14:1256210 pubmed publisher

Mellergaard M, Skovbakke S, Jepsen S, Panagiotopoulou N, Hansen A, Tian W, et al. Clinical Staphylococcus aureus inhibits human T-cell activity through interaction with the PD-1 receptor. MBio. 2023;14:e0134923 pubmed publisher

Zeng S, Zeng M, Yuan S, He L, Jin Y, Huang J, et al. Discovery of potent and selective HPK1 inhibitors based on the 2,4-disubstituted pyrimidine scaffold with immune modulatory properties for ameliorating T cell exhaustion. Bioorg Chem. 2023;139:106728 pubmed publisher

da Costa Teixeira L, Avelar N, Peixoto M, Parentoni A, Santos J, Pereira F, et al. Inflammatory biomarkers at different stages of Sarcopenia in older women. Sci Rep. 2023;13:10367 pubmed publisher

Lan X, Yang T, Wang Y, Qu B, Rong S, Song N. Characterization of 405B8H3(D-E), a newly engineered high affinity chimeric LAG-3 antibody with potent antitumor activity. FEBS Open Bio. 2023;13:1253-1265 pubmed publisher

Palaniyandi S, Strattan E, Kumari R, Mysinger M, Hakim N, Kesler M, et al. Combinatorial inhibition of Tec kinases BTK and ITK is beneficial in ameliorating murine sclerodermatous chronic graft versus host disease. Bone Marrow Transplant. 2023;58:924-935 pubmed publisher

Rasoulouniriana D, Santana Magal N, Gutwillig A, Farhat Younis L, Tal L, Amar S, et al. T Cells Expressing a Modified FcγRI Exert Antibody-Dependent Cytotoxicity and Overcome the Limitations of CAR T-cell Therapy against Solid Tumors. Cancer Immunol Res. 2023;11:792-809 pubmed publisher

Teixeira L, Dos Santos J, Parentoni A, Lima L, Duarte T, Brant F, et al. Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study. J Clin Med. 2022;11: pubmed publisher

Zhang Y, Zhuang Q, Wang F, Zhang C, Xu C, Gu A, et al. Co-expression IL-15 receptor alpha with IL-15 reduces toxicity via limiting IL-15 systemic exposure during CAR-T immunotherapy. J Transl Med. 2022;20:432 pubmed publisher

Yekehfallah V, Pahlavanneshan S, Sayadmanesh A, Momtahan Z, Ma B, Basiri M. Generation and Functional Characterization of PLAP CAR-T Cells against Cervical Cancer Cells. Biomolecules. 2022;12: pubmed publisher

Amormino C, Tedeschi V, Paldino G, Arcieri S, Fiorillo M, Paiardini A, et al. SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity. Cells. 2022;11: pubmed publisher

Rosewell Shaw A, Porter C, Biegert G, Jatta L, Suzuki M. HydrAd: A Helper-Dependent Adenovirus Targeting Multiple Immune Pathways for Cancer Immunotherapy. Cancers (Basel). 2022;14: pubmed publisher

Passariello M, Yoshioka A, Takahashi K, Hashimoto S, Rapuano Lembo R, Manna L, et al. Novel Bi-Specific Immuno-Modulatory Tribodies Potentiate T Cell Activation and Increase Anti-Tumor Efficacy. Int J Mol Sci. 2022;23: pubmed publisher

Tosiek M, Groesser K, Pekcec A, Zwirek M, Murugesan G, Borges E. Activation of the Innate Immune Checkpoint CLEC5A on Myeloid Cells in the Absence of Danger Signals Modulates Macrophages' Function but Does Not Trigger the Adaptive T Cell Immune Response. J Immunol Res. 2022;2022:9926305 pubmed publisher

Vetrei C, Passariello M, Froechlich G, Rapuano Lembo R, Sasso E, Zambrano N, et al. Novel Combinations of Human Immunomodulatory mAbs Lacking Cardiotoxic Effects for Therapy of TNBC. Cancers (Basel). 2021;14: pubmed publisher

Xiao Y, Chen P, Luo C, Xu Z, Li X, Liu L, et al. Discovery of a novel anti PD-L1 X TIGIT bispecific antibody for the treatment of solid tumors. Cancer Treat Res Commun. 2021;29:100467 pubmed publisher

Eidell K, LOVY A, Sylvain N, Scangarello F, Muendlein H, Ophir M, et al. LFA-1 and Kindlin-3 enable the collaborative transport of SLP-76 microclusters by myosin and dynein motors. J Cell Sci. 2021;: pubmed publisher

Shi S, Zhao Q, Ke C, Long S, Zhang F, Zhang X, et al. Loureirin B Exerts its Immunosuppressive Effects by Inhibiting STIM1/Orai1 and KV1.3 Channels. Front Pharmacol. 2021;12:685092 pubmed publisher

Aschmoneit N, Steinlein S, Kühl L, Seifert O, Kontermann R. A scDb-based trivalent bispecific antibody for T-cell-mediated killing of HER3-expressing cancer cells. Sci Rep. 2021;11:13880 pubmed publisher

Sun R, Zhou Y, Han L, Pan Z, Chen J, Zong H, et al. A Rational Designed Novel Bispecific Antibody for the Treatment of GBM. Biomedicines. 2021;9: pubmed publisher

Vetrei C, Passariello M, Froechlich G, Rapuano Lembo R, Zambrano N, De Lorenzo C. Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments. Cancers (Basel). 2021;13: pubmed publisher

Tewari R, Shayahati B, Fan Y, Akimzhanov A. T cell receptor-dependent S-acylation of ZAP-70 controls activation of T cells. J Biol Chem. 2021;:100311 pubmed publisher

Kathamuthu G, Moideen K, Sridhar R, Baskaran D, Babu S. Altered plasma levels of βC and γC chain cytokines and post-treatment modulation in tuberculous lymphadenitis. Cytokine. 2021;138:155405 pubmed publisher

Lee H, Jeong G. Aromadendrin Inhibits T Cell Activation via Regulation of Calcium Influx and NFAT Activity. Molecules. 2020;25: pubmed publisher

Li L, Gao Y, Srivastava R, Wang W, Xiong Q, Fang Z, et al. Lentiviral delivery of combinatorial CAR/CRISPRi circuit into human primary T cells is enhanced by TBK1/IKKɛ complex inhibitor BX795. J Transl Med. 2020;18:363 pubmed publisher

Liu M, Wang X, Li W, Yu X, FLORES VILLANUEVA P, Xu Monette Z, et al. Targeting PD-L1 in non-small cell lung cancer using CAR T cells. Oncogenesis. 2020;9:72 pubmed publisher

Passariello M, Vetrei C, Sasso E, Froechlich G, Gentile C, D Alise A, et al. Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells. Cancers (Basel). 2020;12: pubmed publisher

Evnouchidou I, Chappert P, Benadda S, Zucchetti A, Weimershaus M, Bens M, et al. IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses. Nat Commun. 2020;11:2779 pubmed publisher

Herrera M, Vera C, Keynan Y, Rueda Z. Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review. J Immunol Res. 2020;2020:8074183 pubmed publisher

Guedan S, Madar A, Casado Medrano V, Shaw C, Wing A, Liu F, et al. Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability. J Clin Invest. 2020;130:3087-3097 pubmed publisher

Passariello M, Camorani S, Vetrei C, Ricci S, Cerchia L, De Lorenzo C. Ipilimumab and Its Derived EGFR Aptamer-Based Conjugate Induce Efficient NK Cell Activation against Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher

Vis B, Hewitt R, Monie T, Fairbairn C, Turner S, Kinrade S, et al. Ultrasmall silica nanoparticles directly ligate the T cell receptor complex. Proc Natl Acad Sci U S A. 2020;117:285-291 pubmed publisher

Martinez Hervas S, SÁnchez GarcÍa V, Herrero Cervera A, Vinue A, Real J, Ascaso J, et al. Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes. J Transl Med. 2019;17:222 pubmed publisher

Celis Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Gregoire C, et al. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep. 2019;27:3315-3330.e7 pubmed publisher

Su L, Pan P, Yan P, Long Y, Zhou X, Wang X, et al. Role of vimentin in modulating immune cell apoptosis and inflammatory responses in sepsis. Sci Rep. 2019;9:5747 pubmed publisher

Siddiqui H, Haniffa H, Jabeen A, Rahman A, Choudhary M. Sulphamethazine derivatives as immunomodulating agents: New therapeutic strategies for inflammatory diseases. PLoS ONE. 2018;13:e0208933 pubmed publisher

Diener C, Hart M, Alansary D, Poth V, Walch Rückheim B, Menegatti J, et al. Modulation of intracellular calcium signaling by microRNA-34a-5p. Cell Death Dis. 2018;9:1008 pubmed publisher

Liu R, Merola J, Manes T, Qin L, Tietjen G, Lopez Giraldez F, et al. Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight. 2018;3: pubmed publisher

Dekkema G, Abdulahad W, Bijma T, Moran S, Ryan L, Little M, et al. Urinary and serum soluble CD25 complements urinary soluble CD163 to detect active renal anti-neutrophil cytoplasmic autoantibody-associated vasculitis: a cohort study. Nephrol Dial Transplant. 2019;34:234-242 pubmed publisher

Guedan S, Posey A, Shaw C, Wing A, Da T, Patel P, et al. Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation. JCI Insight. 2018;3: pubmed publisher

Li W, Wu Y, Kong D, Yang H, Wang Y, Shao J, et al. One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells. Sci Rep. 2017;7:9130 pubmed publisher

Graci J, Michaels D, Chen G, Schiralli Lester G, Nodder S, Weetall M, et al. Identification of benzazole compounds that induce HIV-1 transcription. PLoS ONE. 2017;12:e0179100 pubmed publisher

Kathamuthu G, Moideen K, Bhaskaran D, Sekar G, Sridhar R, Vidyajayanthi B, et al. Reduced systemic and mycobacterial antigen-stimulated concentrations of IL-1β and IL-18 in tuberculous lymphadenitis. Cytokine. 2017;90:66-72 pubmed publisher

Blewett M, Xie J, Zaro B, Backus K, Altman A, Teijaro J, et al. Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells. Sci Signal. 2016;9:rs10 pubmed publisher

Bouchet J, Del Río Iñiguez I, Lasserre R, Agüera González S, Cuche C, Danckaert A, et al. Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation. EMBO J. 2016;35:1160-74 pubmed publisher

Grundy S, Plumb J, Kaur M, Ray D, Singh D. Additive anti-inflammatory effects of corticosteroids and phosphodiesterase-4 inhibitors in COPD CD8 cells. Respir Res. 2016;17:9 pubmed publisher

Guirado E, Mbawuike U, Keiser T, Arcos J, Azad A, Wang S, et al. Characterization of host and microbial determinants in individuals with latent tuberculosis infection using a human granuloma model. MBio. 2015;6:e02537-14 pubmed publisher

Tanaka K, Ohgo Y, Katayanagi Y, Yasui K, Hiramoto S, Ikemoto H, et al. Anti-inflammatory effects of green soybean extract irradiated with visible light. Sci Rep. 2014;4:4732 pubmed publisher

Kis Toth K, Tsokos G. Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival. J Immunol. 2014;192:4436-42 pubmed publisher

Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, et al. The aryl hydrocarbon receptor is functionally upregulated early in the course of human T-cell activation. Eur J Immunol. 2014;44:1330-40 pubmed publisher

Rao M, Vogelzang A, Kaiser P, Schuerer S, Kaufmann S, Gengenbacher M. The tuberculosis vaccine candidate Bacillus Calmette-Guérin ?ureC::hly coexpressing human interleukin-7 or -18 enhances antigen-specific T cell responses in mice. PLoS ONE. 2013;8:e78966 pubmed publisher

Yu F, Wang X, Guo Z, Bartlett D, Gottschalk S, Song X. T-cell engager-armed oncolytic vaccinia virus significantly enhances antitumor therapy. Mol Ther. 2014;22:102-11 pubmed publisher

Kim H, Na B, Kwon M, Ko Y, Han W, Jun C. Dynamic motile T cells highly respond to the T cell stimulation via PI3K-Akt and NF-?B pathways. PLoS ONE. 2013;8:e59793 pubmed publisher

Verma N, Dempsey E, Long A, Davies A, Barry S, Fallon P, et al. Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-? signaling. J Biol Chem. 2012;287:27204-16 pubmed publisher

Xu D, Lin L, Lin X, Huang Z, Lei Z. Immunoregulation of autocrine prolactin: suppressing the expression of costimulatory molecules and cytokines in T lymphocytes by prolactin receptor knockdown. Cell Immunol. 2010;263:71-8 pubmed publisher

Reeves E, Williamson M, Byrne B, Bergin D, Smith S, Greally P, et al. IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis. J Immunol. 2010;184:1642-52 pubmed publisher

Lamhamedi Cherradi S, Martin R, Ito T, Kheradmand F, CORRY D, Liu Y, et al. Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12. J Immunol. 2008;180:6000-9 pubmed

Weindl G, Naglik J, Kaesler S, Biedermann T, Hube B, Korting H, et al. Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J Clin Invest. 2007;117:3664-72 pubmed

Schwarz E, Kummerow C, Wenning A, Wagner K, Sappok A, Waggershauser K, et al. Calcium dependence of T cell proliferation following focal stimulation. Eur J Immunol. 2007;37:2723-33 pubmed

Barker S, Grosse S, Siapati E, Kritz A, Kinnon C, Thrasher A, et al. Immunotherapy for neuroblastoma using syngeneic fibroblasts transfected with IL-2 and IL-12. Br J Cancer. 2007;97:210-7 pubmed

Eidenschenk C, Jouanguy E, Alcais A, Mention J, Pasquier B, Fleckenstein I, et al. Familial NK cell deficiency associated with impaired IL-2- and IL-15-dependent survival of lymphocytes. J Immunol. 2006;177:8835-43 pubmed

Smith E, Finney H, Nesbitt A, Ramsdell F, Robinson M. Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation. Immunology. 2006;119:203-11 pubmed

Blumenthal A, Ehlers S, Lauber J, Buer J, Lange C, Goldmann T, et al. The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. Blood. 2006;108:965-73 pubmed

Miranda Carús M, Benito Miguel M, Llamas M, Balsa A, Martin Mola E. Human T cells constitutively express IL-15 that promotes ex vivo T cell homeostatic proliferation through autocrine/juxtacrine loops. J Immunol. 2005;175:3656-62 pubmed

Hajnicka V, Vancova I, Kocakova P, Slovak M, Gasperík J, Slavikova M, et al. Manipulation of host cytokine network by ticks: a potential gateway for pathogen transmission. Parasitology. 2005;130:333-42 pubmed

Misra A, Dube A, Naik S. Immune responses in normal Indian langur monkeys (Presbytis entellus)--a primate model for visceral leishmaniasis. J Med Primatol. 2004;33:65-9 pubmed

Finney H, Akbar A, Lawson A. Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain. J Immunol. 2004;172:104-13 pubmed

Quemeneur L, Flacher M, Gerland L, Ffrench M, Revillard J, Bonnefoy Berard N. Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis. J Immunol. 2002;169:2747-55 pubmed