product summary
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company name :
R&D Systems
product type :
ELISA/assay
product name :
Mouse IL-6R alpha DuoSet ELISA
catalog :
DY1830
quantity :
1 Kit (for 15 Plates)
price :
850 USD
more info or order :
citations: 12
Reference
Flynn C, Garbers Y, Düsterhöft S, Wichert R, Lokau J, Lehmann C, et al. Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro. Sci Rep. 2020;10:21612 pubmed publisher
Uyama N, Tsutsui H, Wu S, Yasuda K, Hatano E, Qin X, et al. Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation. Sci Rep. 2019;9:17558 pubmed publisher
McGregor N, Murat M, Elango J, Poulton I, Walker E, Crimeen Irwin B, et al. IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis. J Biol Chem. 2019;294:7850-7863 pubmed publisher
Li B, Wang X, Choi I, Wang Y, Liu S, Pham A, et al. miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. J Clin Invest. 2017;127:3702-3716 pubmed publisher
Tode J, Richert E, Koinzer S, Klettner A, Pickhinke U, Garbers C, et al. Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in mice. Cytokine. 2017;96:8-15 pubmed publisher
Cho S, Pirih F, Koh A, Michalski M, Eber M, Ritchie K, et al. The soluble interleukin-6 receptor is a mediator of hematopoietic and skeletal actions of parathyroid hormone. J Biol Chem. 2013;288:6814-25 pubmed publisher
Wunderlich C, Delic D, Behnke K, Meryk A, Ströhle P, Chaurasia B, et al. Cutting edge: Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in mice. J Immunol. 2012;188:4141-4 pubmed publisher
Arndt P, Strahan B, Wang Y, Long C, Horiuchi K, Walcheck B. Leukocyte ADAM17 regulates acute pulmonary inflammation. PLoS ONE. 2011;6:e19938 pubmed publisher
Jones G, McLoughlin R, Hammond V, Parker C, Williams J, Malhotra R, et al. Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. J Immunol. 2010;184:2130-9 pubmed publisher
Matsumoto S, Hara T, Mitsuyama K, Yamamoto M, Tsuruta O, Sata M, et al. Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model. J Immunol. 2010;184:1543-51 pubmed publisher
Wan S, Zhou Z, Duan B, Morel L. Direct B cell stimulation by dendritic cells in a mouse model of lupus. Arthritis Rheum. 2008;58:1741-50 pubmed publisher
Coles B, Fielding C, Rose John S, Scheller J, Jones S, O Donnell V. Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo. Am J Pathol. 2007;171:315-25 pubmed
image
image 1 :
R&D Systems DY1830 image 1
Mouse IL-6 R alpha ELISA Standard Curve
product information
master code :
DY1830
SKU :
DY1830
product name :
Mouse IL-6R alpha DuoSet ELISA
unit size :
1 Kit (for 15 Plates)
description :
The Mouse IL-6R alpha DuoSet ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse IL-6R alpha.
target :
IL-6R alpha
category :
ELISAs
species :
Mouse
gene symbol :
Il6ra
kit type :
Solid Phase Sandwich ELISA
elisaRange :
46.90 - 3000 pg/mL
top caption :
Mouse IL-6 R alpha ELISA Standard Curve
applications :
ELISA
USD :
850 USD
alt names :
CD126, gp80, IL-6 R alpha, IL6Q, IL6R, IL6R alpha, IL-6R-1, IL6RA, IL-6RA, IL6RQ, interleukin 6 receptor
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.