This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human IL-29/IL-28B (IFN-lambda 1/3) DuoSet ELISA
catalog :
DY1598B-05
quantity :
1 Kit (for 5 Plates) (also 1 Kit (for 15 Plates))
price :
440 USD
citations: 33
Reference
Reuschl A, Thorne L, Whelan M, Ragazzini R, Furnon W, Cowton V, et al. Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants. Nat Microbiol. 2024;9:451-463 pubmed publisher
De M, Sukla S, Bharatiya S, Keshri S, Roy D, Roy S, et al. IFN-λ3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans. Infect Immun. 2024;92:e0050423 pubmed publisher
Schutt W, Conde J, Mladinich M, Himmler G, Mackow E. ZIKV induction of tristetraprolin in endothelial and Sertoli cells post-transcriptionally inhibits IFNβ/λ expression and promotes ZIKV persistence. MBio. 2023;14:e0174223 pubmed publisher
Sugimoto A, Numaguchi T, Chihama R, Takenaka Y, Sato Y. Identification of novel lactic acid bacteria with enhanced protective effects against influenza virus. PLoS ONE. 2023;18:e0273604 pubmed publisher
St xf6 lting H, Baillon L, Frise R, Bonner K, Hewitt R, Molyneaux P, et al. Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1. Mucosal Immunol. 2022;15:952-963 pubmed publisher
Gibson A, Sateriale A, Dumaine J, Engiles J, Pardy R, Gullicksrud J, et al. A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition. PLoS Pathog. 2022;18:e1010003 pubmed publisher
Steiner A, Hrovat Schaale K, Prigione I, Yu C, Laohamonthonkul P, Harapas C, et al. Deficiency in coatomer complex I causes aberrant activation of STING signalling. Nat Commun. 2022;13:2321 pubmed publisher
Song Y, Hou G, Diep J, Ooi Y, Akopyants N, Beverley S, et al. Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation. Nucleic Acids Res. 2021;49:12706-12715 pubmed publisher
Oh S, Shin O. SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response. Cells. 2021;10: pubmed publisher
Hendricks M, Lane S, Melvin J, Ouyang Y, Stolz D, Williams J, et al. Extracellular vesicles promote transkingdom nutrient transfer during viral-bacterial co-infection. Cell Rep. 2021;34:108672 pubmed publisher
Hjorton K, Hagberg N, Pucholt P, Eloranta M, Rönnblom L. The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells. Arthritis Res Ther. 2020;22:130 pubmed publisher
Alam J, Lee A, Lee J, Kwon D, Park H, Park J, et al. Dysbiotic oral microbiota and infected salivary glands in Sjögren's syndrome. PLoS ONE. 2020;15:e0230667 pubmed publisher
Xu H, Xu S, Xie S, Zhang Y, Yang J, Zhang W, et al. MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway. elife. 2019;8: pubmed publisher
Niwa M, Fujisawa T, Mori K, Yamanaka K, Yasui H, Suzuki Y, et al. IL-17A Attenuates IFN-? Expression by Inducing Suppressor of Cytokine Signaling Expression in Airway Epithelium. J Immunol. 2018;: pubmed publisher
Colavita F, Bordoni V, Caglioti C, Biava M, Castilletti C, Bordi L, et al. ZIKV Infection Induces an Inflammatory Response but Fails to Activate Types I, II, and III IFN Response in Human PBMC. Mediators Inflamm. 2018;2018:2450540 pubmed publisher
Ding S, Diep J, Feng N, Ren L, Li B, Ooi Y, et al. STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection. Nat Commun. 2018;9:1485 pubmed publisher
Ueno N, Nishimura N, Ueno S, Endo S, Tatetsu H, Hirata S, et al. PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4. Oncogene. 2017;36:4481-4497 pubmed publisher
Akoto C, Davies D, Swindle E. Mast cells are permissive for rhinovirus replication: potential implications for asthma exacerbations. Clin Exp Allergy. 2017;47:351-360 pubmed publisher
Telcian A, Zdrenghea M, Edwards M, Laza Stanca V, Mallia P, Johnston S, et al. Vitamin D increases the antiviral activity of bronchial epithelial cells in vitro. Antiviral Res. 2017;137:93-101 pubmed publisher
Lalle E, Bordi L, Caglioti C, Garbuglia A, Castilletti C, Taibi C, et al. IFN-Alpha receptor-1 upregulation in PBMC from HCV naïve patients carrying cc genotype. possible role of IFN-lambda. PLoS ONE. 2014;9:e93434 pubmed publisher
Dolganiuc A, Kodys K, Marshall C, Saha B, Zhang S, Bala S, et al. Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cells. PLoS ONE. 2012;7:e44915 pubmed publisher
Yin Z, Dai J, Deng J, Sheikh F, Natalia M, Shih T, et al. Type III IFNs are produced by and stimulate human plasmacytoid dendritic cells. J Immunol. 2012;189:2735-45 pubmed publisher
Bierne H, Travier L, Mahlakõiv T, Tailleux L, Subtil A, Lebreton A, et al. Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta. PLoS ONE. 2012;7:e39080 pubmed publisher
Popugaeva E, Witkowski P, Schlegel M, Ulrich R, Auste B, Rang A, et al. Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humans. PLoS ONE. 2012;7:e35587 pubmed publisher
Donnelly O, Errington Mais F, Steele L, Hadac E, Jennings V, Scott K, et al. Measles virus causes immunogenic cell death in human melanoma. Gene Ther. 2013;20:7-15 pubmed publisher
Sancho Shimizu V, Pérez de Diego R, Lorenzo L, Halwani R, Alangari A, Israelsson E, et al. Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency. J Clin Invest. 2011;121:4889-902 pubmed publisher
Zahn S, Rehkämper C, Kummerer B, Ferring Schmidt S, Bieber T, Tüting T, et al. Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFN?) in cutaneous lupus erythematosus. J Invest Dermatol. 2011;131:133-40 pubmed publisher
Pietila T, Latvala S, Osterlund P, Julkunen I. Inhibition of dynamin-dependent endocytosis interferes with type III IFN expression in bacteria-infected human monocyte-derived DCs. J Leukoc Biol. 2010;88:665-74 pubmed publisher
Stoltz M, Klingstrom J. Alpha/beta interferon (IFN-alpha/beta)-independent induction of IFN-lambda1 (interleukin-29) in response to Hantaan virus infection. J Virol. 2010;84:9140-8 pubmed publisher
Krausgruber T, Saliba D, Ryzhakov G, Lanfrancotti A, Blazek K, Udalova I. IRF5 is required for late-phase TNF secretion by human dendritic cells. Blood. 2010;115:4421-30 pubmed publisher
Megjugorac N, Gallagher G, Gallagher G. IL-4 enhances IFN-lambda1 (IL-29) production by plasmacytoid DCs via monocyte secretion of IL-1Ra. Blood. 2010;115:4185-90 pubmed publisher
Wang Q, Nagarkar D, Bowman E, Schneider D, Gosangi B, Lei J, et al. Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses. J Immunol. 2009;183:6989-97 pubmed publisher
Wolk K, Witte K, Witte E, Proesch S, Schulze Tanzil G, Nasilowska K, et al. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes. J Leukoc Biol. 2008;83:1181-93 pubmed publisher
product information
master code :
DY1598B
SKU :
DY1598B-05
product name :
Human IL-29/IL-28B (IFN-lambda 1/3) DuoSet ELISA
unit size :
1 Kit (for 5 Plates) (also 1 Kit (for 15 Plates))
description :
The Human IL-29/IL-28B (IFN-lambda 1/3) DuoSet ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human IL-29/IL-28B IFN-lambda 1/3).
target :
IL-29/IL-28B (IFN-lambda 1/3)
category :
ELISAs
species :
Human
gene symbol :
IFNL1
kit type :
Solid Phase Sandwich ELISA
elisaRange :
62.50 - 4000 pg/mL
top caption :
Human IL-29/ IL-28B (IFN-lambda 1/ 3) ELISA Standard Curve
applications :
ELISA
USD :
440 USD
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.