This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human MICA DuoSet ELISA
catalog :
DY1300
quantity :
1 Kit (for 15 Plates)
price :
850 USD
citations: 33
Reference
Kowash R, Sabnani M, Gray L, Deng Q, Girard L, Naito Y, et al. A novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models. bioRxiv. 2024;: pubmed publisher
Seller A, Tegeler C, Mauermann J, Schreiber T, Hagelstein I, Liebel K, et al. Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome. Int J Mol Sci. 2024;25: pubmed publisher
Wang C, Tan K, Wu Y, Zheng J, Wu J, Chen J. Functional MICA Variants Are Differentially Associated with Immune-Mediated Inflammatory Diseases. Int J Mol Sci. 2024;25: pubmed publisher
Lee M, Leong M, Rustagi A, Beck A, Zeng L, Holmes S, et al. SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D. Cell Rep. 2022;41:111892 pubmed publisher
Masuhiro K, Tamiya M, Fujimoto K, Koyama S, Naito Y, Osa A, et al. Bronchoalveolar lavage fluid reveals factors contributing to the efficacy of PD-1 blockade in lung cancer. JCI Insight. 2022;7: pubmed publisher
Samarkanova D, Cox S, Hernandez D, Rodriguez L, Pérez M, Madrigal A, et al. Cord blood and amniotic membrane extract eye drop preparations display immune-suppressive and regenerative properties. Sci Rep. 2021;11:13754 pubmed publisher
Wang C, Tan K, Jan Wu Y, Lin J, Zheng J, Yu A, et al. MICA*019 Allele and Soluble MICA as Biomarkers for Ankylosing Spondylitis in Taiwanese. J Pers Med. 2021;11: pubmed publisher
Wu X, Zhang Y, Li Y, Schmidt Wolf I. Increase of Antitumoral Effects of Cytokine-Induced Killer Cells by Antibody-Mediated Inhibition of MICA Shedding. Cancers (Basel). 2020;12: pubmed publisher
Muñoz D, Yannone S, Daemen A, Sun Y, Vakar Lopez F, Kawahara M, et al. Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging. JCI Insight. 2019;5: pubmed publisher
Sakiyama M, Espinoza I, Reddy A, de Carlo F, Kumar A, Levenson A, et al. Race-associated expression of MHC class I polypeptide-related sequence A (MICA) in prostate cancer. Exp Mol Pathol. 2019;108:173-182 pubmed publisher
Chen J, Chang C, Huang Y, Kuo H, Chen T, Wang C, et al. Persistently elevated soluble MHC class I polypeptide-related sequence A and transforming growth factor-β1 levels are poor prognostic factors in head and neck squamous cell carcinoma after definitive chemoradiotherapy. PLoS ONE. 2018;13:e0202224 pubmed publisher
Fan X, Wang P, Zhang C, Zhang Y, Fu Y, Zhang C, et al. All-trans retinoic acid enhances cytotoxicity of CIK cells against human lung adenocarcinoma by upregulating MICA and IL-2 secretion. Sci Rep. 2017;7:16481 pubmed publisher
Ghadially H, Brown L, Lloyd C, Lewis L, LEWIS A, Dillon J, et al. MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue. Br J Cancer. 2017;116:1208-1217 pubmed publisher
Huang C, Huang C, Yeh M, Wang S, Chen K, Ko Y, et al. Genetics Variants and Serum Levels of MHC Class I Chain-related A in Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients Post Antiviral Treatment. EBioMedicine. 2017;15:81-89 pubmed publisher
Ke M, Wang H, Zhou Y, Li J, Liu Y, Zhang M, et al. SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice. Oncotarget. 2016;7:49509-49526 pubmed publisher
Isernhagen A, Malzahn D, Viktorova E, Elsner L, Monecke S, von Bonin F, et al. The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation. EMBO Mol Med. 2015;7:1480-502 pubmed publisher
Zingoni A, Cecere F, Vulpis E, Fionda C, Molfetta R, Soriani A, et al. Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells. J Immunol. 2015;195:736-48 pubmed publisher
Cox S, Laza Briviesca R, Pearson H, Soria B, Gibson D, Gomez S, et al. Umbilical cord blood plasma contains soluble NKG2D ligands that mediate loss of natural killer cell function and cytotoxicity. Eur J Immunol. 2015;45:2324-34 pubmed publisher
González Foruria I, Santulli P, Chouzenoux S, Carmona F, Batteux F, Chapron C. Soluble ligands for the NKG2D receptor are released during endometriosis and correlate with disease severity. PLoS ONE. 2015;10:e0119961 pubmed publisher
Ullrich N, Heinemann A, Nilewski E, Scheffrahn I, Klode J, Scherag A, et al. CEACAM1-3S Drives Melanoma Cells into NK Cell-Mediated Cytolysis and Enhances Patient Survival. Cancer Res. 2015;75:1897-907 pubmed publisher
Dambrauskas Z, Svensson H, Joshi M, Hyltander A, Naredi P, Iresjö B. Expression of major histocompatibility complex class I-related chain A/B (MICA/B) in pancreatic carcinoma. Int J Oncol. 2014;44:99-104 pubmed publisher
Giuliani M, Bennaceur Griscelli A, Nanbakhsh A, Oudrhiri N, Chouaib S, Azzarone B, et al. TLR ligands stimulation protects MSC from NK killing. Stem Cells. 2014;32:290-300 pubmed publisher
Reiners K, Kessler J, Sauer M, Rothe A, Hansen H, Reusch U, et al. Rescue of impaired NK cell activity in hodgkin lymphoma with bispecific antibodies in vitro and in patients. Mol Ther. 2013;21:895-903 pubmed publisher
Kumar V, Yi Lo P, Sawai H, Kato N, Takahashi A, Deng Z, et al. Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma. PLoS ONE. 2012;7:e44743 pubmed
Yamanegi K, Yamane J, Kobayashi K, Kato Kogoe N, Ohyama H, Nakasho K, et al. Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma cells to Fas- and NK cell-mediated cell death. Int J Oncol. 2012;41:83-91 pubmed publisher
Mamessier E, Sylvain A, Thibult M, Houvenaeghel G, Jacquemier J, Castellano R, et al. Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity. J Clin Invest. 2011;121:3609-22 pubmed publisher
Kumar V, Kato N, Urabe Y, Takahashi A, Muroyama R, Hosono N, et al. Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Nat Genet. 2011;43:455-8 pubmed publisher
Muntasell A, Magri G, Pende D, Angulo A, Lopez Botet M. Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection. Blood. 2010;115:5170-9 pubmed publisher
Stanzer S, Janesch B, Resel M, Augustin T, Samonigg H, Bauernhofer T. The role of activation-induced cell death in the higher onset of spontaneous apoptosis of NK cell subsets in patients with metastatic epithelial cancer. Cell Immunol. 2010;261:99-104 pubmed publisher
Ho V, Vanneman M, Kim H, Sasada T, Kang Y, Pasek M, et al. Biologic activity of irradiated, autologous, GM-CSF-secreting leukemia cell vaccines early after allogeneic stem cell transplantation. Proc Natl Acad Sci U S A. 2009;106:15825-30 pubmed publisher
Abe Y, Muto M, Nieda M, Nakagawa Y, Nicol A, Kaneko T, et al. Clinical and immunological evaluation of zoledronate-activated Vgamma9gammadelta T-cell-based immunotherapy for patients with multiple myeloma. Exp Hematol. 2009;37:956-68 pubmed publisher
Cerboni C, Ardolino M, Santoni A, Zingoni A. Detuning CD8+ T lymphocytes by down-regulation of the activating receptor NKG2D: role of NKG2D ligands released by activated T cells. Blood. 2009;113:2955-64 pubmed publisher
Siemens D, Hu N, Sheikhi A, Chung E, Frederiksen L, Pross H, et al. Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide. Cancer Res. 2008;68:4746-53 pubmed publisher
product information
master code :
DY1300
SKU :
DY1300
product name :
Human MICA DuoSet ELISA
unit size :
1 Kit (for 15 Plates)
description :
The Human MICA DuoSet ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human MICA.
target :
MICA
category :
ELISAs
species :
Human
gene symbol :
MICA
kit type :
Solid Phase Sandwich ELISA
elisaRange :
62.50 - 4000 pg/mL
top caption :
Human MICA ELISA Standard Curve
applications :
ELISA
USD :
850 USD
alt names :
FLJ60820, MGC111087, PERB11.1
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.