This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human CXCL5/ENA-78 Quantikine ELISA Kit
catalog :
DX000
quantity :
1 Kit
price :
655 USD
citations: 36
Reference
Di Y, Wang Z, Xiao J, Zhang X, Ye L, Wen X, et al. ACSL6-activated IL-18R1-NF-κB promotes IL-18-mediated tumor immune evasion and tumor progression. Sci Adv. 2024;10:eadp0719 pubmed publisher
Zhou J, Xu W, Wu Y, Wang M, Zhang N, Wang L, et al. GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway. Oncogene. 2023;42:3319-3330 pubmed publisher
Chen C, Lin L, Chen J, Chang T. CXCL5 suppression recovers neovascularization and accelerates wound healing in diabetes mellitus. Cardiovasc Diabetol. 2023;22:172 pubmed publisher
Xiao G, Kumar R, Komuro Y, Burguet J, Kakarla V, Azizkhanian I, et al. IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury. Cell Rep. 2022;41:111848 pubmed publisher
Sorrentino C, D Antonio L, Ciummo S, Fieni C, Landuzzi L, Ruzzi F, et al. CRISPR/Cas9-mediated deletion of Interleukin-30 suppresses IGF1 and CXCL5 and boosts SOCS3 reducing prostate cancer growth and mortality. J Hematol Oncol. 2022;15:145 pubmed publisher
Wu T, Wang W, Shi G, Hao M, Wang Y, Yao M, et al. Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression. Cell Death Dis. 2022;13:624 pubmed publisher
Lin N, Chen L, Zhang Y, Yang Y, Zhang L, Chen L, et al. KIF4A promotes tumor progression of bladder cancer via CXCL5 dependent myeloid-derived suppressor cells recruitment. Sci Rep. 2022;12:6015 pubmed publisher
Kobari L, Auclair M, Piau O, Ferrand N, Zaoui M, Delhommeau F, et al. Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells. Leukemia. 2022;36:540-548 pubmed publisher
Tsui K, Chang K, Sung H, Hsu S, Lin Y, Hou C, et al. Mucosa-Associated Lymphoid Tissue 1 Is an Oncogene Inducing Cell Proliferation, Invasion, and Tumor Growth via the Upregulation of NF-κB Activity in Human Prostate Carcinoma Cells. Biomedicines. 2021;9: pubmed publisher
Ando Y, Ohuchida K, Otsubo Y, Kibe S, Takesue S, Abe T, et al. Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5. PLoS ONE. 2020;15:e0228015 pubmed publisher
Flaherty E, Zhu S, Barretto N, Cheng E, Deans P, Fernando M, et al. Neuronal impact of patient-specific aberrant NRXN1α splicing. Nat Genet. 2019;51:1679-1690 pubmed publisher
Fong L, Hotson A, Powderly J, Sznol M, Heist R, Choueiri T, et al. Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer. Cancer Discov. 2020;10:40-53 pubmed publisher
Liu W, Wang P, Xie Z, Wang S, Ma M, Li J, et al. Abnormal inhibition of osteoclastogenesis by mesenchymal stem cells through the miR-4284/CXCL5 axis in ankylosing spondylitis. Cell Death Dis. 2019;10:188 pubmed publisher
Taki M, Abiko K, Baba T, Hamanishi J, Yamaguchi K, Murakami R, et al. Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation. Nat Commun. 2018;9:1685 pubmed publisher
Qiu W, Zhang H, Xia W, Ke L, Yang J, Yu Y, et al. The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling. J Exp Clin Cancer Res. 2018;37:85 pubmed publisher
Zhang D, Zhou J, Tang D, Zhou L, Chou L, Chou K, et al. Neutrophil infiltration mediated by CXCL5 accumulation in the laryngeal squamous cell carcinoma microenvironment: A mechanism by which tumour cells escape immune surveillance. Clin Immunol. 2017;175:34-40 pubmed publisher
Tzeng T, Tsay H, Chang L, Hsu C, Lai T, Huang F, et al. Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid. J Biomed Sci. 2013;20:90 pubmed publisher
Feng X, Scheinberg P, Samsel L, Rios O, Chen J, McCoy J, et al. Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura. J Thromb Haemost. 2012;10:1616-23 pubmed publisher
Sung S, Hsieh C, Law A, Zhau H, Pathak S, Multani A, et al. Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis. Cancer Res. 2008;68:9996-10003 pubmed publisher
Lee Y, Kweon S, Kwon K, Park J, Yoon T, Park B. Inhibition of IL-1beta-mediated inflammatory responses by the IkappaB alpha super-repressor in human fibroblast-like synoviocytes. Biochem Biophys Res Commun. 2009;378:90-4 pubmed publisher
Skov L, Beurskens F, Zachariae C, Reitamo S, Teeling J, Satijn D, et al. IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis. J Immunol. 2008;181:669-79 pubmed
Lee S, Nam W, Na H, Cho Y, Ha K, Hwang J, et al. CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation. Biochem Pharmacol. 2008;76:79-90 pubmed publisher
Lee Y, Lee J, Noh E, Kim E, Song M, Jung W, et al. Guggulsterone blocks IL-1beta-mediated inflammatory responses by suppressing NF-kappaB activation in fibroblast-like synoviocytes. Life Sci. 2008;82:1203-9 pubmed publisher
Flanagan K, Modrusan Z, Cornelius J, Chavali A, Kasman I, Komuves L, et al. Intestinal epithelial cell up-regulation of LY6 molecules during colitis results in enhanced chemokine secretion. J Immunol. 2008;180:3874-81 pubmed
Matsuda A, Fukuda S, Matsumoto K, Saito H. Th1/Th2 cytokines reciprocally regulate in vitro pulmonary angiogenesis via CXC chemokine synthesis. Am J Respir Cell Mol Biol. 2008;38:168-75 pubmed
Newcomb D, Sajjan U, Nagarkar D, Goldsmith A, Bentley J, Hershenson M. Cooperative effects of rhinovirus and TNF-{alpha} on airway epithelial cell chemokine expression. Am J Physiol Lung Cell Mol Physiol. 2007;293:L1021-8 pubmed
Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, et al. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease. J Clin Invest. 2007;117:1951-60 pubmed
Dimberg J, Dienus O, Lofgren S, Hugander A, Wågsäter D. Expression and gene polymorphisms of the chemokine CXCL5 in colorectal cancer patients. Int J Oncol. 2007;31:97-102 pubmed
Antoniou K, Tzouvelekis A, Alexandrakis M, Sfiridaki K, Tsiligianni I, Rachiotis G, et al. Different angiogenic activity in pulmonary sarcoidosis and idiopathic pulmonary fibrosis. Chest. 2006;130:982-8 pubmed
Abe Y, Fornage M, Yang C, Bui Thanh N, Wise V, Chen H, et al. L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. Atherosclerosis. 2007;192:56-66 pubmed
Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol. 2005;175:6177-89 pubmed
Gessler P, Pretre R, Hohl V, Rousson V, Fischer J, Dahinden C. CXC-chemokine stimulation of neutrophils correlates with plasma levels of myeloperoxidase and lactoferrin and contributes to clinical outcome after pediatric cardiac surgery. Shock. 2004;22:513-20 pubmed
Suzumori N, Katano K, Suzumori K. Peritoneal fluid concentrations of epithelial neutrophil-activating peptide-78 correlate with the severity of endometriosis. Fertil Steril. 2004;81:305-8 pubmed
Doubrovina E, Doubrovin M, Vider E, Sisson R, O Reilly R, Dupont B, et al. Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma. J Immunol. 2003;171:6891-9 pubmed
Maheshwari A, Christensen R, Calhoun D. ELR+ CXC chemokines in human milk. Cytokine. 2003;24:91-102 pubmed
Ciesielski C, Andreakos E, Foxwell B, Feldmann M. TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion. Eur J Immunol. 2002;32:2037-45 pubmed
product information
master code :
DX000
SKU :
DX000
product name :
Human CXCL5/ENA-78 Quantikine ELISA Kit
unit size :
1 Kit
description :
The Human CXCL5/ENA-78 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human CXCL5/ENA-78 in cell culture supernates (10 ul), serum (25 ul), edta plasma (50 ul), platelet-poor heparin plasma (50 ul), citrate plasma (50 ul).
target :
CXCL5/ENA-78
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human ENA-78
gene symbol :
CXCL5
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (10 uL), Serum (25 uL), EDTA Plasma (50 uL), Platelet-poor Heparin Plasma (50 uL), Citrate Plasma (50 uL)
elisaSensitivity :
15 pg/mL
elisaRange :
31.20 - 2000 pg/mL
top caption :
Human CXCL5/ENA-78 ELISA Cell Culture Supernate Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human ENA-78 Immunoassay is a 4.5 hour solid phase ELISA designed to measure human ENA-78 in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant human ENA-78 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant human ENA-78 accurately. Results obtained using natural human ENA-78 showed dose curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human ENA-78.
alt names :
chemokine (C-C motif) ligand 5, C-X-C motif chemokine 5, CXCL5, ENA78, ENA-78, ENA-78(1-78), Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, neutrophil-activating protein 78, SCYB5ENA78
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.