| Reference |
|---|
Moon S, Kim H, Kim J, Kim J, Choi J, Won S, et al. An examination of the mechanisms driving the therapeutic effects of an AAV expressing a soluble variant of VEGF receptor-1. PLoS ONE. 2024;19:e0305466 pubmed publisher |
M xe4 enp xe4 xe4 N, Tiainen L, H xe4 m xe4 l xe4 inen M, Luukkaala T, Tanner M, Lahdenper xe4 O, et al. Neuropilin-1 and placental growth factor as prognostic factors in metastatic breast cancer. BMC Cancer. 2024;24:331 pubmed publisher |
Donohue J, Gruen D, Iyanna N, Lorence J, Brown J, Guyette F, et al. Mechanism matters: mortality and endothelial cell damage marker differences between blunt and penetrating traumatic injuries across three prehospital clinical trials. Sci Rep. 2024;14:2747 pubmed publisher |
Zhao J, Duan R, Sun J, Chow R, Lyons T, Yu J. An Examination of the Effect of Aspirin and Salicylic Acid on Soluble Fms-like Tyrosine Kinase-1 Release from Human Placental Trophoblasts. Cells. 2024;13: pubmed publisher |
Pintye D, Sziva R, Mastyugin M, Young B, Jacas S, T xf6 r xf6 k M, et al. A Novel Dual-Function Redox Modulator Relieves Oxidative Stress and Anti-Angiogenic Response in Placental Villus Explant Exposed to Hypoxia-Relevance for Preeclampsia Therapy. Biology (Basel). 2023;12: pubmed publisher |
Yang Z, Jia X, Deng Q, Luo M, Hou Y, Yue J, et al. Human umbilical cord mesenchymal stem cell-derived extracellular vesicles loaded with TFCP2 activate Wnt/β-catenin signaling to alleviate preeclampsia. Int Immunopharmacol. 2023;115:109732 pubmed publisher |
Huang X, Jia L, Jia Y, Xu X, Wang R, Wei M, et al. sFlt-1-enriched exosomes induced endothelial cell dysfunction and a preeclampsia-like phenotype in mice. Cytokine. 2023;166:156190 pubmed publisher |
Liu X, Li Z, Sun J, Zhang Z, Li W. Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophages. BMC Cancer. 2023;23:259 pubmed publisher |
Kurlak L, Scaife P, Briggs L, Broughton Pipkin F, Gardner D, Mistry H. Alterations in Antioxidant Micronutrient Concentrations in Placental Tissue, Maternal Blood and Urine and the Fetal Circulation in Pre-eclampsia. Int J Mol Sci. 2023;24: pubmed publisher |
Dymara Konopka W, Laskowska M, Grywalska E, Hymos A, B x142 a x17c ewicz A, Leszczy x144 ska Gorzelak B. Similar Pro- and Antiangiogenic Profiles Close to Delivery in Different Clinical Presentations of Two Pregnancy Syndromes: Preeclampsia and Fetal Growth Restriction. Int J Mol Sci. 2023;24: pubmed publisher |
Kaur J, Kamboj K, Yadav A, Kaur P, Kumar V, Jha V. Cholecalciferol supplementation and angiogenic markers in chronic kidney disease. PLoS ONE. 2022;17:e0268946 pubmed publisher |
Anto E, Coall D, Asiamah E, Afriyie O, Addai Mensah O, Wiafe Y, et al. Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia. PLoS ONE. 2022;17:e0265717 pubmed publisher |
Fondjo L, Amoah B, Annan J, Adu Gyamfi E, Asamaoh E. Hematobiochemical variability and predictors of new-onset and persistent postpartum preeclampsia. Sci Rep. 2022;12:3583 pubmed publisher |
Nuzzo A, Moretti L, Mele P, Todros T, Eva C, Rolfo A. Effect of Placenta-Derived Mesenchymal Stromal Cells Conditioned Media on an LPS-Induced Mouse Model of Preeclampsia. Int J Mol Sci. 2022;23: pubmed publisher |
Wada H, Shinozaki T, Suzuki M, Sakagami S, Ajiro Y, Funada J, et al. Impact of Chronic Kidney Disease on the Associations of Cardiovascular Biomarkers With Adverse Outcomes in Patients With Suspected or Known Coronary Artery Disease: The EXCEED-J Study. J Am Heart Assoc. 2022;11:e023464 pubmed publisher |
Silva J, Qi X, Grant M, Boulton M. Spatial and temporal VEGF receptor intracellular trafficking in microvascular and macrovascular endothelial cells. Sci Rep. 2021;11:17400 pubmed publisher |
Jia T, Jacquet T, Dalonneau F, Coudert P, Vaganay E, Exbrayat Héritier C, et al. FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells. BMC Biol. 2021;19:173 pubmed publisher |
Nabweyambo S, Sande O, McGovern N, Bwanga F, Ssekagiri A, Keesiga A, et al. Circulating levels of angiogenic factors and their association with preeclampsia among pregnant women at Mulago National Referral Hospital in Uganda. PLoS ONE. 2021;16:e0251227 pubmed publisher |
Kim S, Park M, Kim J, Kim T, Hwang J, Ha K, et al. Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia. Cells. 2020;9: pubmed publisher |
Barbara R, Piotr R, Kornel B, El x17c bieta Z, Danuta R, Eduardo N. Divergent Impact of Breast Cancer Laterality on Clinicopathological, Angiogenic, and Hemostatic Profiles: A Potential Role of Tumor Localization in Future Outcomes. J Clin Med. 2020;9: pubmed publisher |
Wilson D, Howard M, Fung A, O Donoghue F, Barnes M, Lappas M, et al. Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy. PLoS ONE. 2020;15:e0232287 pubmed publisher |
Rahman R, Murthi P, Singh H, Gurungsinghe S, Leaw B, Mockler J, et al. Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia. Int J Mol Sci. 2020;21: pubmed publisher |
Nikuei P, Rajaei M, Roozbeh N, Mohseni F, Poordarvishi F, Azad M, et al. Diagnostic accuracy of sFlt1/PlGF ratio as a marker for preeclampsia. BMC Pregnancy Childbirth. 2020;20:80 pubmed publisher |
Scurt F, Menne J, Brandt S, Bernhardt A, Mertens P, Haller H, et al. Systemic Inflammation Precedes Microalbuminuria in Diabetes. Kidney Int Rep. 2019;4:1373-1386 pubmed publisher |
Dias M, Araujo V, Vasconcelos T, Li Q, Hauswirth W, Linden R, et al. Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat. Gene Ther. 2019;26:479-490 pubmed publisher |
Zarychta E, Rhone P, Bielawski K, Michalska M, Rosc D, Ruszkowska Ciastek B. Anti-angiogenic efficacy in invasive breast carcinoma patients depends on clinicopathological determinants. Adv Med Sci. 2019;64:216-223 pubmed publisher |
Varas Godoy M, Acuña Gallardo S, Venegas Duarte S, Hill C, Caceres Verschae A, Realini O, et al. Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia. Stem Cells Int. 2019;2019:1916542 pubmed publisher |
Unger H, Hansa A, Buffet C, Hasang W, Teo A, Randall L, et al. Sulphadoxine-pyrimethamine plus azithromycin may improve birth outcomes through impacts on inflammation and placental angiogenesis independent of malarial infection. Sci Rep. 2019;9:2260 pubmed publisher |
Abou Faycal C, Gazzeri S, Eymin B. A VEGF-A/SOX2/SRSF2 network controls VEGFR1 pre-mRNA alternative splicing in lung carcinoma cells. Sci Rep. 2019;9:336 pubmed publisher |
Villie P, Lefevre G, Arrestier R, Rousseau A, Berkane N, Hertig A. ELABELA concentration is not decreased in maternal plasma before the onset of preeclampsia. Am J Obstet Gynecol. 2019;220:284-285 pubmed publisher |
Lee S, Kim H, Shin O, Choi J, Kim J, Cho Y, et al. Intravitreal Injection of AAV Expressing Soluble VEGF Receptor-1 Variant Induces Anti-VEGF Activity and Suppresses Choroidal Neovascularization. Invest Ophthalmol Vis Sci. 2018;59:5398-5407 pubmed publisher |
Sandgren J, Deng G, Linggonegoro D, Scroggins S, Perschbacher K, Nair A, et al. Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice. JCI Insight. 2018;3: pubmed publisher |
Sullivan J, Stanek L, Lukason M, Bu J, Osmond S, Barry E, et al. Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain. Gene Ther. 2018;25:205-219 pubmed publisher |
Stødle G, Silva G, Tangerås L, Gierman L, Nervik I, Dahlberg U, et al. Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts. Clin Exp Immunol. 2018;193:84-94 pubmed publisher |
Tanaka H, Kumasawa K, Kakigano A, Mimura K, Endo M, Tomimatsu T, et al. Arginase controls soluble vascular endothelial growth factor receptor 1 (sFlt1) to maintain pregnancy homeostasis. Biochem Biophys Res Commun. 2018;499:150-155 pubmed publisher |
Li H, Yao J, Chang X, Wu J, Duan T, Wang K. LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia. Reproduction. 2018;155:297-306 pubmed publisher |
Eslani M, Putra I, Shen X, Hamouie J, Afsharkhamseh N, Besharat S, et al. Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1. Invest Ophthalmol Vis Sci. 2017;58:5507-5517 pubmed publisher |
O Brien M, Baczyk D, Kingdom J. Endothelial Dysfunction in Severe Preeclampsia is Mediated by Soluble Factors, Rather than Extracellular Vesicles. Sci Rep. 2017;7:5887 pubmed publisher |
Dutta A, Brito K, Khramstova G, Mueller A, Chinthala S, Alexander D, et al. Household air pollution and angiogenic factors in pregnant Nigerian women: A randomized controlled ethanol cookstove intervention. Sci Total Environ. 2017;599-600:2175-2181 pubmed publisher |
Pantho A, Price M, Ashraf A, Wajid U, Khansari M, Jahan A, et al. Synthetic Receptors Induce Anti Angiogenic and Stress Signaling on Human First Trimester Cytotrophoblast Cells. Int J Environ Res Public Health. 2017;14: pubmed publisher |
Jammalamadaga V, Abraham P. Spectrum of Factors Triggering Endothelial Dysfunction in PIH. J Clin Diagn Res. 2016;10:BC14-BC17 pubmed publisher |
Takano S, Ishikawa E, Matsuda M, Sakamoto N, Akutsu H, Yamamoto T, et al. The anti-angiogenic role of soluble-form VEGF receptor in malignant gliomas. Int J Oncol. 2017;50:515-524 pubmed publisher |
Panta S, Yamakuchi M, Shimizu T, Takenouchi K, Oyama Y, Koriyama T, et al. Low grade inflammation inhibits VEGF induced HUVECs migration in p53 dependent manner. Biochem Biophys Res Commun. 2017;483:803-809 pubmed publisher |
Ataga K, Derebail V, Caughey M, Elsherif L, Shen J, Jones S, et al. Albuminuria Is Associated with Endothelial Dysfunction and Elevated Plasma Endothelin-1 in Sickle Cell Anemia. PLoS ONE. 2016;11:e0162652 pubmed publisher |
Weel I, Baergen R, Romão Veiga M, Borges V, Ribeiro V, Witkin S, et al. Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia. PLoS ONE. 2016;11:e0157584 pubmed publisher |
Souders C, Maynard S, Yan J, Wang Y, Boatright N, Sedan J, et al. Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia. Int J Mol Sci. 2015;16:12436-53 pubmed publisher |
Bessho H, Wong B, Huang D, Siew E, Huang D, Tan J, et al. Inhibition of placental growth factor in renal cell carcinoma. Anticancer Res. 2015;35:531-41 pubmed |
Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla Herttuala S, et al. Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer. BMC Cancer. 2014;14:696 pubmed publisher |
Owen L, Morrison M, Ahn J, Woo S, Sato H, Robinson R, et al. FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression. Invest Ophthalmol Vis Sci. 2014;55:3543-54 pubmed publisher |
White W, Garrett A, Craici I, Wagner S, Fitz Gibbon P, Butters K, et al. Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury. PLoS ONE. 2014;9:e92693 pubmed publisher |
Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, et al. Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy. Br J Cancer. 2014;110:26-33 pubmed publisher |
Liu L, Yang T, Ji J, Wen Q, Morgan A, Jin B, et al. Integrating multiple 'omics' analyses identifies serological protein biomarkers for preeclampsia. BMC Med. 2013;11:236 pubmed publisher |
El Tarhouny S, Almasry S, Elfayomy A, Baghdadi H, Habib F. Placental growth factor and soluble Fms-like tyrosine kinase 1 in diabetic pregnancy: A possible relation to distal villous immaturity. Histol Histopathol. 2014;29:259-72 pubmed publisher |
Justiniano S, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda J, et al. Fc? receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies. J Biol Chem. 2013;288:26800-9 pubmed publisher |
Huang Q, Wang S, Zhang M, Huang L, Tian J, Yu Y, et al. Advanced oxidation protein products enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts: a possible link between oxidative stress and preeclampsia. Placenta. 2013;34:949-52 pubmed publisher |
Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Ito K, et al. A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment. PLoS ONE. 2013;8:e61483 pubmed publisher |
Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, et al. Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin an. Cytokine. 2013;61:755-8 pubmed publisher |
Patten I, Rana S, Shahul S, Rowe G, Jang C, Liu L, et al. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. Nature. 2012;485:333-8 pubmed publisher |
Landt S, Heidecke H, Korlach S, Reuter C, Schwidde I, Barinoff J, et al. In vitro vascular tube formation testing as a tool for treatment individualisation in patients with cervical cancer. Anticancer Res. 2011;31:2609-15 pubmed |
Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stöblen F, et al. Prognostic significance of angiogenic factors in uterine cervical cancer. Anticancer Res. 2011;31:2589-95 pubmed |
Rahbari N, Schmidt T, Falk C, Hinz U, Herber M, Bork U, et al. Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer. BMC Cancer. 2011;11:286 pubmed publisher |
DuBois S, Shusterman S, Ingle A, Ahern C, Reid J, Wu B, et al. Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study. Clin Cancer Res. 2011;17:5113-22 pubmed publisher |
Jeyabalan A, Powers R, Clifton R, Van Dorsten P, Hauth J, Klebanoff M, et al. Effect of smoking on circulating angiogenic factors in high risk pregnancies. PLoS ONE. 2010;5:e13270 pubmed publisher |
Powers R, Jeyabalan A, Clifton R, Van Dorsten P, Hauth J, Klebanoff M, et al. Soluble fms-Like tyrosine kinase 1 (sFlt1), endoglin and placental growth factor (PlGF) in preeclampsia among high risk pregnancies. PLoS ONE. 2010;5:e13263 pubmed publisher |
Jeevaratnam K, Nadarajah V, Judson J, Nalliah S, Abdullah M. Periodic assessment of plasma sFlt-1 and PlGF concentrations and its association with placental morphometry in gestational hypertension (GH) - a prospective follow-up study. BMC Pregnancy Childbirth. 2010;10:58 pubmed publisher |
Kosugi T, Nakayama T, Li Q, Chiodo V, Zhang L, Campbell Thompson M, et al. Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice. Am J Physiol Renal Physiol. 2010;298:F609-16 pubmed publisher |
Levine R, Vatten L, Horowitz G, Qian C, Romundstad P, Yu K, et al. Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study. BMJ. 2009;339:b4336 pubmed publisher |
Verlohren S, Galindo A, Schlembach D, Zeisler H, Herraiz I, Moertl M, et al. An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia. Am J Obstet Gynecol. 2010;202:161.e1-161.e11 pubmed publisher |
Bourlev V, Iljasova N, Adamyan L, Larsson A, Olovsson M. Signs of reduced angiogenic activity after surgical removal of deeply infiltrating endometriosis. Fertil Steril. 2010;94:52-7 pubmed publisher |
Sandhofer A, Tatarczyk T, Kirchmair R, Iglseder B, Paulweber B, Patsch J, et al. Are plasma VEGF and its soluble receptor sFlt-1 atherogenic risk factors? Cross-sectional data from the SAPHIR study. Atherosclerosis. 2009;206:265-9 pubmed publisher |
Sallinen H, Anttila M, Narvainen J, Koponen J, Hamalainen K, Kholova I, et al. Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice. Mol Ther. 2009;17:278-84 pubmed publisher |
Muehlenbachs A, Fried M, Lachowitzer J, Mutabingwa T, Duffy P. Natural selection of FLT1 alleles and their association with malaria resistance in utero. Proc Natl Acad Sci U S A. 2008;105:14488-91 pubmed publisher |
FINDLEY C, Mitchell R, Duscha B, Annex B, Kontos C. Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease. J Am Coll Cardiol. 2008;52:387-93 pubmed publisher |
Jeyabalan A, Powers R, Durica A, Harger G, Roberts J, Ness R. Cigarette smoke exposure and angiogenic factors in pregnancy and preeclampsia. Am J Hypertens. 2008;21:943-7 pubmed publisher |
Gutman G, Barak V, Maslovitz S, Amit A, Lessing J, Geva E. Regulation of vascular endothelial growth factor-A and its soluble receptor sFlt-1 by luteinizing hormone in vivo: implication for ovarian follicle angiogenesis. Fertil Steril. 2008;89:922-6 pubmed publisher |
Clavel G, Bessis N, Lemeiter D, Fardellone P, Mejjad O, Menard J, et al. Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction. Clin Immunol. 2007;124:158-64 pubmed |
Caine G, Ryan P, Lip G, Blann A. Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients. Cancer Lett. 2007;251:296-301 pubmed |
Levine R, Lam C, Qian C, Yu K, Maynard S, Sachs B, et al. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med. 2006;355:992-1005 pubmed |
Wallner W, Sengenberger R, Strick R, Strissel P, Meurer B, Beckmann M, et al. Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction. Clin Sci (Lond). 2007;112:51-7 pubmed |
Caine G, Stonelake P, Lip G, Blann A. Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer. Cancer Lett. 2007;248:131-6 pubmed |
Masuyama H, Suwaki N, Nakatsukasa H, Masumoto A, Tateishi Y, Hiramatrsu Y. Circulating angiogenic factors in preeclampsia, gestational proteinuria, and preeclampsia superimposed on chronic glomerulonephritis. Am J Obstet Gynecol. 2006;194:551-6 pubmed |
Mross K, Drevs J, Müller M, Medinger M, Marme D, Hennig J, et al. Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours. Eur J Cancer. 2005;41:1291-9 pubmed |
Buhimschi C, Norwitz E, Funai E, Richman S, Guller S, Lockwood C, et al. Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia. Am J Obstet Gynecol. 2005;192:734-41 pubmed |
Li H, Gu B, Zhang Y, Lewis D, Wang Y. Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta. Placenta. 2005;26:210-7 pubmed |
Levine R, Thadhani R, Qian C, Lam C, Lim K, Yu K, et al. Urinary placental growth factor and risk of preeclampsia. JAMA. 2005;293:77-85 pubmed |
Eubank T, Roberts R, Galloway M, Wang Y, Cohn D, Marsh C. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity. 2004;21:831-42 pubmed |
Levine R, Maynard S, Qian C, Lim K, England L, Yu K, et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med. 2004;350:672-83 pubmed |
Maynard S, Min J, Merchan J, Lim K, Li J, Mondal S, et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest. 2003;111:649-58 pubmed |
