Human VEGF-C Quantikine ELISA Kit | R&D Systems DVEC00 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human VEGF-C Quantikine ELISA Kit

catalog :

DVEC00

quantity :

1 Kit

price :

655 USD

citations: 54

Reference
Meshko B, Volatier T, Mann J, Kluth M, Ganss C, Frank M, et al. Anti-Inflammatory and Anti-(Lymph)angiogenic Properties of an ABCB5+ Limbal Mesenchymal Stem Cell Population. Int J Mol Sci. 2024;25: pubmed publisher
Francavilla F, Sarcina F, Schepetkin I, Kirpotina L, Contino M, Schirizzi A, et al. Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models. Eur J Med Chem. 2023;261:115854 pubmed publisher
Chachaj A, Stanimirova I, Chabowski M, Gomu x142 kiewicz A, Hodurek P, Glatzel Pluci x144 ska N, et al. Sodium accumulation in the skin is associated with higher density of skin lymphatic vessels in patients with arterial hypertension. Adv Med Sci. 2023;68:276-289 pubmed publisher
Szymczak A, Kusztal M, Go x142 x119 biowski T, Letachowicz K, Go x17a dzik A, Ko x15b cielska Kasprzak K, et al. High Plasma Angiopoietin-2 Levels Predict the Need to Initiate Dialysis within Two Years in Patients with Chronic Kidney Disease. Int J Mol Sci. 2023;24: pubmed publisher
Iwanek G, Ponikowska B, Zdanowicz A, Fudim M, Hurkacz M, Zymli x144 ski R, et al. Relationship of Vascular Endothelial Growth Factor C, a Lymphangiogenesis Modulator, With Edema Formation, Congestion and Outcomes in Acute Heart Failure. J Card Fail. 2023;: pubmed publisher
Suzuki J, Shimizu Y, Hayashi T, Che Y, Pu Z, Tsuzuki K, et al. Hydrogen Sulfide Attenuates Lymphedema Via the Induction of Lymphangiogenesis Through a PI3K/Akt-Dependent Mechanism. J Am Heart Assoc. 2022;11:e026889 pubmed publisher
Zhong J, Yang H, Shelton E, Matsusaka T, Clark A, Yermalitsky V, et al. Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury. JCI Insight. 2022;7: pubmed publisher
Biswas Shivhare S, Lu Q, Sun D, Hou H, Bulmer J, Innes B, et al. Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding-endometrial disorder. Reprod Biomed Online. 2022;45:531-543 pubmed publisher
Miller I, Khan S, Shiels L, Das S, O Farrell A, Connor K, et al. Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects. Cancer Med. 2022;11:3820-3836 pubmed publisher
Li Y, Liu C, Zhang X, Huang X, Liang S, Xing F, et al. CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/β-catenin signalling pathway. Br J Cancer. 2022;126:1684-1694 pubmed publisher
Wada I, Nakao S, Yamaguchi M, Kaizu Y, Arima M, Sawa S, et al. Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1+ Macrophage Infiltration. Invest Ophthalmol Vis Sci. 2021;62:17 pubmed publisher
Mashima T, Wakatsuki T, Kawata N, Jang M, Nagamori A, Yoshida H, et al. Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo. Sci Rep. 2021;11:15125 pubmed publisher
Sevinc M, Hasbal N, Basturk T, Ozcafer P, Kocas B, Kiliçkesmez K, et al. Comparison of lung ultrasound and other volumetric methods in peritoneal dialysis patients. Medicine (Baltimore). 2021;100:e23856 pubmed publisher
Li W, Hsiao K, Wang C, Chang N, Hsu P, Sun C, et al. Extracellular vesicle-associated VEGF-C promotes lymphangiogenesis and immune cells infiltration in endometriosis. Proc Natl Acad Sci U S A. 2020;117:25859-25868 pubmed publisher
Reglero C, Lafarga V, Rivas V, Albitre Á, Ramos P, Berciano S, et al. GRK2-Dependent HuR Phosphorylation Regulates HIF1α Activation under Hypoxia or Adrenergic Stress. Cancers (Basel). 2020;12: pubmed publisher
Wada H, Suzuki M, Matsuda M, Ajiro Y, Shinozaki T, Sakagami S, et al. Distinct Characteristics of VEGF-D and VEGF-C to Predict Mortality in Patients With Suspected or Known Coronary Artery Disease. J Am Heart Assoc. 2020;9:e015761 pubmed publisher
Dudek A, Liu L, Gupta S, Logan T, Singer E, Joshi M, et al. Phase Ib/II Clinical Trial of Pembrolizumab With Bevacizumab for Metastatic Renal Cell Carcinoma: BTCRC-GU14-003. J Clin Oncol. 2020;38:1138-1145 pubmed publisher
Jha S, Rauniyar K, Chronowska E, Mattonet K, Maina E, Koistinen H, et al. KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D. elife. 2019;8: pubmed publisher
Wang R, Yamada T, Arai S, Fukuda K, Taniguchi H, Tanimoto A, et al. Distribution and Activity of Lenvatinib in Brain Tumor Models of Human Anaplastic Thyroid Cancer Cells in Severe Combined Immune Deficient Mice. Mol Cancer Ther. 2019;18:947-956 pubmed publisher
Schwager S, Renner S, Hemmerle T, Karaman S, Proulx S, Fetz R, et al. Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation. JCI Insight. 2018;3: pubmed publisher
Harris A, Perez M, Munson J. Docetaxel facilitates lymphatic-tumor crosstalk to promote lymphangiogenesis and cancer progression. BMC Cancer. 2018;18:718 pubmed publisher
Li C, Jiang X, Lin B, Hong H, Zhu S, Jiang L, et al. RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway. Onco Targets Ther. 2018;11:2875-2890 pubmed publisher
Jiang X, Li C, Lin B, Hong H, Jiang L, Zhu S, et al. cIAP2 promotes gallbladder cancer invasion and lymphangiogenesis by activating the NF-κB pathway. Cancer Sci. 2017;108:1144-1156 pubmed publisher
Bastos D, Paupert J, Maillard C, Seguin F, Carvalho M, Agostini M, et al. Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model. Lab Invest. 2017;97:194-206 pubmed publisher
Daly K, Stack M, Eisenga M, Keane J, Zurakowski D, Blume E, et al. Vascular endothelial growth factor A is associated with the subsequent development of moderate or severe cardiac allograft vasculopathy in pediatric heart transplant recipients. J Heart Lung Transplant. 2017;36:434-442 pubmed publisher
Chou C, Modo M. Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling. Sci Rep. 2016;6:29029 pubmed publisher
Tokumoto M, Tanaka H, Tauchi Y, Kasashima H, Kurata K, Yashiro M, et al. Identification of tumour-reactive lymphatic endothelial cells capable of inducing progression of gastric cancer. Br J Cancer. 2015;113:1046-54 pubmed publisher
Tutunea Fatan E, Majumder M, Xin X, Lala P. The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis. Mol Cancer. 2015;14:35 pubmed publisher
Kimura H, Mikami D, Kamiyama K, Sugimoto H, Kasuno K, Takahashi N, et al. Telmisartan, a possible PPAR-Î´ agonist, reduces TNF-Î±-stimulated VEGF-C production by inhibiting the p38MAPK/HSP27 pathway in human proximal renal tubular cells. Biochem Biophys Res Commun. 2014;454:320-7 pubmed publisher
Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla Herttuala S, et al. Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer. BMC Cancer. 2014;14:696 pubmed publisher
Weinkopff T, Mackenzie C, Eversole R, Lammie P. Filarial excretory-secretory products induce human monocytes to produce lymphangiogenic mediators. PLoS Negl Trop Dis. 2014;8:e2893 pubmed publisher
Yang M, Kim H, Lee K, Yang S, Lee J, Lee K, et al. KML001 inhibits cell proliferation and invasion in pancreatic cancer cells through suppression of NF-?B and VEGF-C. Anticancer Res. 2014;34:3469-74 pubmed
Decio A, Taraboletti G, Patton V, Alzani R, Perego P, Fruscio R, et al. Vascular endothelial growth factor c promotes ovarian carcinoma progression through paracrine and autocrine mechanisms. Am J Pathol. 2014;184:1050-1061 pubmed publisher
Armstrong A, Haggman M, Stadler W, Gingrich J, Assikis V, Polikoff J, et al. Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer. Clin Cancer Res. 2013;19:6891-901 pubmed publisher
Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, et al. Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin an. Cytokine. 2013;61:755-8 pubmed publisher
Yazdani S, Poosti F, Kramer A, Mirković K, Kwakernaak A, Hovingh M, et al. Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis. PLoS ONE. 2012;7:e50209 pubmed publisher
Lin C, Chen S, Lin C, Chang C, Lin Y, Tai Y, et al. Lysophosphatidic acid enhances vascular endothelial growth factor-C expression in human prostate cancer PC-3 cells. PLoS ONE. 2012;7:e41096 pubmed publisher
Majumder M, Tutunea Fatan E, Xin X, Rodriguez Torres M, Torres Garcia J, Wiebe R, et al. Co-expression of ?9?1 integrin and VEGF-D confers lymphatic metastatic ability to a human breast cancer cell line MDA-MB-468LN. PLoS ONE. 2012;7:e35094 pubmed publisher
Harmon C, DePrimo S, Raymond E, Cheng A, Boucher E, Douillard J, et al. Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib. J Transl Med. 2011;9:120 pubmed publisher
Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stöblen F, et al. Prognostic significance of angiogenic factors in uterine cervical cancer. Anticancer Res. 2011;31:2589-95 pubmed
Scheel C, Eaton E, Li S, Chaffer C, Reinhardt F, Kah K, et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell. 2011;145:926-40 pubmed publisher
Konings I, de Jonge M, Burger H, van der Gaast A, van Beijsterveldt L, Winkler H, et al. Phase I and pharmacological study of the broad-spectrum tyrosine kinase inhibitor JNJ-26483327 in patients with advanced solid tumours. Br J Cancer. 2010;103:987-92 pubmed publisher
Ha C, Wu J, Irmak S, Lisboa F, Dizon A, Warren J, et al. Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis. Biol Reprod. 2010;83:27-35 pubmed publisher
Onimaru M, Yonemitsu Y, Fujii T, Tanii M, Nakano T, Nakagawa K, et al. VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B. Am J Physiol Heart Circ Physiol. 2009;297:H1685-96 pubmed publisher
Zhu A, Sahani D, Duda D, di Tomaso E, Ancukiewicz M, Catalano O, et al. Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J Clin Oncol. 2009;27:3027-35 pubmed publisher
Machnik A, Neuhofer W, Jantsch J, Dahlmann A, Tammela T, Machura K, et al. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med. 2009;15:545-52 pubmed publisher
Rini B, Michaelson M, Rosenberg J, Bukowski R, Sosman J, Stadler W, et al. Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. J Clin Oncol. 2008;26:3743-8 pubmed publisher
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, et al. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp Hematol. 2008;36:1035-46 pubmed publisher
Huang V, Lonsdorf A, Fang L, Kakinuma T, Lee V, Cha E, et al. Cutting edge: rapid accumulation of epidermal CCL27 in skin-draining lymph nodes following topical application of a contact sensitizer recruits CCR10-expressing T cells. J Immunol. 2008;180:6462-6 pubmed
Simiantonaki N, Jayasinghe C, Michel Schmidt R, Peters K, Hermanns M, Kirkpatrick C. Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines. Int J Oncol. 2008;32:585-92 pubmed
Lee C, Tien H, Hu C, Chou W, Lin L. Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia. Br J Cancer. 2007;97:877-82 pubmed
Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, et al. Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells. 2007;25:1862-71 pubmed
Laakkonen P, Waltari M, Holopainen T, Takahashi T, Pytowski B, Steiner P, et al. Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth. Cancer Res. 2007;67:593-9 pubmed
Lin J, Lalani A, Harding T, Gonzalez M, Wu W, Luan B, et al. Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor. Cancer Res. 2005;65:6901-9 pubmed

product information

master code :

DVEC00

SKU :

DVEC00

product name :

Human VEGF-C Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human VEGF-C Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human VEGF-C in cell culture supernates (50 ul), serum (10 ul), edta plasma (50 ul), platelet-poor plasma (50 ul), heparin plasma (50 ul).

target :

VEGF-C

category :

ELISAs

species :

Human

specificity :

Natural human VEGF-C, recombinant human VEGF-C (wild type), and recombinant human VEGF-C (Cys156Ser substituted)

gene symbol :

VEGFC

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (50 uL), Platelet-poor Plasma (50 uL), Heparin Plasma (50 uL)

elisaSensitivity :

48.4 pg/mL

elisaRange :

109.00 - 7000 pg/mL

top caption :

Human VEGF-C ELISA Cell Culture Supernate Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human VEGF-C Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human VEGF-C in cell culture supernates, serum, and plasma. It contains recombinant human VEGF-C (Cys156Ser substituted) and has been shown to accurately quantitate the recombinant factor. Results obtained using recombinant human VEGF-C (wild type) and natural human VEGF-C showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human VEGF-C.

alt names :

Flt4 ligand, Flt4-L, vascular endothelial growth factor C, Vascular endothelial growth factor-related protein, VEGFC, VEGF-C, VRPFLT4 ligand DHM

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.