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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human CCL11/Eotaxin Quantikine ELISA Kit
catalog :
DTX00
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 34
Reference
Zhang S, Dong D, Zhang Y, Wang J, Liu L, Zhao Y. miR-124-3p relieves allergic rhinitis by inhibiting dipeptidyl peptidase-4. Int Immunopharmacol. 2021;101:108279 pubmed publisher
Ravichandran S, Grubbs G, Tang J, Lee Y, Huang C, Golding H, et al. Systemic and mucosal immune profiling in asymptomatic and symptomatic SARS-CoV-2-infected individuals reveal unlinked immune signatures. Sci Adv. 2021;7:eabi6533 pubmed publisher
Scabia G, Testa G, Scali M, Del Turco S, Desiato G, Berardi N, et al. Reduced ccl11/eotaxin mediates the beneficial effects of environmental stimulation on the aged hippocampus. Brain Behav Immun. 2021;98:234-244 pubmed publisher
Zhou F, Liu P, Lv H, Gao Z, Chang W, Xu Y. miR-31 attenuates murine allergic rhinitis by suppressing interleukin-13-induced nasal epithelial inflammatory responses. Mol Med Rep. 2021;23: pubmed publisher
Han M, Kim S, Oh I, Kim Y, Lee J. Serum IL-1β can be a biomarker in children with severe persistent allergic rhinitis. Allergy Asthma Clin Immunol. 2019;15:58 pubmed publisher
Butcher L, Pérès K, André P, Morris R, Walter S, Dartigues J, et al. Association between plasma CCL11 (eotaxin-1) and cognitive status in older adults: Differences between rural and urban dwellers. Exp Gerontol. 2018;113:173-179 pubmed publisher
Sun M, Huang Y, Li F, Li H, Zhang B, Jin L. MicroRNA-874 inhibits TNF-α-induced remodeling in human fetal airway smooth muscle cells by targeting STAT3. Respir Physiol Neurobiol. 2018;251:34-40 pubmed publisher
Cherry J, Stein T, Tripodis Y, Alvarez V, Huber B, Au R, et al. CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer's disease. PLoS ONE. 2017;12:e0185541 pubmed publisher
Johdi N, Mazlan L, Sagap I, Jamal R. Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps. Cytokine. 2017;99:35-42 pubmed publisher
Boström E, Kindstedt E, Sulniute R, Palmqvist P, Majster M, Holm C, et al. Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines. PLoS ONE. 2015;10:e0134608 pubmed publisher
Pallis F, Conran N, Fertrin K, Olalla Saad S, Costa F, Franco Penteado C. Hydroxycarbamide reduces eosinophil adhesion and degranulation in sickle cell anaemia patients. Br J Haematol. 2014;164:286-95 pubmed publisher
Provost V, Langlois A, Chouinard F, Rola Pleszczynski M, Chakir J, Flamand N, et al. Leukotriene D4 and interleukin-13 cooperate to increase the release of eotaxin-3 by airway epithelial cells. PLoS ONE. 2012;7:e43544 pubmed publisher
Houser K, Johnson D, Ishmael F. Anti-inflammatory effects of methoxyphenolic compounds on human airway cells. J Inflamm (Lond). 2012;9:6 pubmed publisher
Bachert C, Zhang N, Holtappels G, De Lobel L, Van Cauwenberge P, Liu S, et al. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J Allergy Clin Immunol. 2010;126:962-8, 968.e1-6 pubmed publisher
Miyagaki T, Sugaya M, Fujita H, Ohmatsu H, Kakinuma T, Kadono T, et al. Eotaxins and CCR3 interaction regulates the Th2 environment of cutaneous T-cell lymphoma. J Invest Dermatol. 2010;130:2304-11 pubmed publisher
Xu G, Zhang L, Wang D, Xu R, Liu Z, Han D, et al. Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells. Allergy. 2010;65:581-9 pubmed publisher
Hartl D, Krauss Etschmann S, Koller B, Hordijk P, Kuijpers T, Hoffmann F, et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol. 2008;181:8053-67 pubmed
Niederfuhr A, Kirsche H, Deutschle T, Poppert S, Riechelmann H, Wellinghausen N. Staphylococcus aureus in nasal lavage and biopsy of patients with chronic rhinosinusitis. Allergy. 2008;63:1359-67 pubmed publisher
Makowska J, Grzegorczyk J, Bienkiewicz B, Wozniak M, Kowalski M. Systemic responses after bronchial aspirin challenge in sensitive patients with asthma. J Allergy Clin Immunol. 2008;121:348-54 pubmed
Miller M, Ramsdell J, Friedman P, Cho J, Renvall M, Broide D. Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema. J Allergy Clin Immunol. 2007;120:1118-25 pubmed
Intapan P, Niwattayakul K, Sawanyawisuth K, Chotmongkol V, Maleewong W. Cerebrospinal fluid eotaxin and eotaxin-2 levels in human eosinophilic meningitis associated with angiostrongyliasis. Cytokine. 2007;39:138-41 pubmed
Emad A, Emad Y. Relationship between eosinophilia and levels of chemokines (CCL5 and CCL11) and IL-5 in bronchoalveolar lavage fluid of patients with mustard gas-induced pulmonary fibrosis. J Clin Immunol. 2007;27:605-12 pubmed
Miyazaki E, Nureki S, Ono E, Ando M, Matsuno O, Fukami T, et al. Circulating thymus- and activation-regulated chemokine/CCL17 is a useful biomarker for discriminating acute eosinophilic pneumonia from other causes of acute lung injury. Chest. 2007;131:1726-34 pubmed
Andrews A, Bucchieri F, Arima K, Izuhara K, Holgate S, Davies D, et al. Effect of IL-13 receptor alpha2 levels on the biological activity of IL-13 variant R110Q. J Allergy Clin Immunol. 2007;120:91-7 pubmed
Igawa K, Satoh T, Hirashima M, Yokozeki H. Regulatory mechanisms of galectin-9 and eotaxin-3 synthesis in epidermal keratinocytes: possible involvement of galectin-9 in dermal eosinophilia of Th1-polarized skin inflammation. Allergy. 2006;61:1385-91 pubmed
Andrews A, Nasir T, Bucchieri F, Holloway J, Holgate S, Davies D. IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts. J Allergy Clin Immunol. 2006;118:858-65 pubmed
Ammit A, Moir L, Oliver B, Hughes J, Alkhouri H, Ge Q, et al. Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2007;292:L199-206 pubmed
Falcone C, Minoretti P, D Angelo A, Buzzi M, Coen E, Emanuele E, et al. Markers of eosinophilic inflammation and risk prediction in patients with coronary artery disease. Eur J Clin Invest. 2006;36:211-7 pubmed
Pang L, Nie M, Corbett L, Sutcliffe A, Knox A. Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities. J Immunol. 2006;176:3788-95 pubmed
Kristjansson S, Bjarnarson S, Wennergren G, Palsdottir A, Arnadottir T, Haraldsson A, et al. Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like response. J Allergy Clin Immunol. 2005;116:805-11 pubmed
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product information
master code :
DTX00
SKU :
DTX00
product name :
Human CCL11/Eotaxin Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human CCL11/Eotaxin Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human CCL11/Eotaxin in cell culture supernates (50 ul), serum (50 ul), edta plasma (50 ul), citrate plasma (50 ul).
target :
CCL11/Eotaxin
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human Eotaxin
gene symbol :
CCL11
kit type :
Solid Phase Sandwich ELISA
assay length :
3.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Citrate Plasma (50 uL)
elisaSensitivity :
5 pg/mL
elisaRange :
15.60 - 1000 pg/mL
top caption :
Human CCL11/Eotaxin ELISA Cell Culture Supernate Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human Eotaxin Immunoassay is a 3.5 hour solid phase ELISA designed to measure human Eotaxin in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant human Eotaxin and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant human Eotaxin accurately. Results obtained measuring natural human eotaxin showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Eotaxin.
alt names :
C-C motif chemokine 11, chemokine (C-C motif) ligand 11, Eosinophil chemotactic protein, Eotaxin, eotaxin-1, MGC22554, SCYA11Small-inducible cytokine A11, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.