Human Tie-2 Quantikine ELISA Kit | R&D Systems DTE200 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human Tie-2 Quantikine ELISA Kit

catalog :

DTE200

quantity :

1 Kit

price :

615 USD

citations: 26

Reference
Moxon J, Kraeuter A, Phie J, Juliano S, Anderson G, Standley G, et al. Serum angiopoietin-1 concentration does not distinguish patients with ischaemic stroke from those presenting to hospital with ischaemic stroke mimics. BMC Cardiovasc Disord. 2022;22:462 pubmed publisher
Kaur J, Kamboj K, Yadav A, Kaur P, Kumar V, Jha V. Cholecalciferol supplementation and angiogenic markers in chronic kidney disease. PLoS ONE. 2022;17:e0268946 pubmed publisher
Dekker N, van Leeuwen A, van Strien W, Majolee J, Szulcek R, Vonk A, et al. Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels. Crit Care. 2019;23:117 pubmed publisher
Shi Y, Yan H, Yuan J, Zhang H, Huang J, Ni Z, et al. Different patterns of inflammatory and angiogenic factors are associated with peritoneal small solute transport and peritoneal protein clearance in peritoneal dialysis patients. BMC Nephrol. 2018;19:119 pubmed publisher
Moritz F, Schniering J, Distler J, Gay R, Gay S, Distler O, et al. Tie2 as a novel key factor of microangiopathy in systemic sclerosis. Arthritis Res Ther. 2017;19:105 pubmed publisher
Gozal D, Khalyfa A, Qiao Z, Smith D, Philby M, Koren D, et al. Angiopoietin-2 and soluble Tie-2 receptor plasma levels in children with obstructive sleep apnea and obesity. Obesity (Silver Spring). 2017;25:1083-1090 pubmed publisher
Hossain M, Shifat R, Johnson D, Bedford M, Gabrusiewicz K, Cortes Santiago N, et al. TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. Sci Adv. 2016;2:e1501290 pubmed
Jongman R, van Klarenbosch J, Molema G, Zijlstra J, de Vries A, van Meurs M. Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass. PLoS ONE. 2015;10:e0136205 pubmed publisher
Wertenbroek M, Schepers M, Kamminga Rasker H, Bottema J, Muller Kobold A, Roelofsen H, et al. Clinical outcome, proteome kinetics and angiogenic factors in serum after thermoablation of colorectal liver metastases. BMC Cancer. 2013;13:266 pubmed publisher
Rasul S, Reiter M, Ilhan A, Lampichler K, Wagner L, Kautzky Willer A. Circulating angiopoietin-2 and soluble Tie-2 in type 2 diabetes mellitus: a cross-sectional study. Cardiovasc Diabetol. 2011;10:55 pubmed publisher
Iribarren C, Phelps B, Darbinian J, McCluskey E, Quesenberry C, Hytopoulos E, et al. Circulating angiopoietins-1 and -2, angiopoietin receptor Tie-2 and vascular endothelial growth factor-A as biomarkers of acute myocardial infarction: a prospective nested case-control study. BMC Cardiovasc Disord. 2011;11:31 pubmed publisher
Boucherat O, Franco Montoya M, Delacourt C, Martinovic J, Masse V, Elie C, et al. Defective angiogenesis in hypoplastic human fetal lungs correlates with nitric oxide synthase deficiency that occurs despite enhanced angiopoietin-2 and VEGF. Am J Physiol Lung Cell Mol Physiol. 2010;298:L849-56 pubmed publisher
Koenecke C, Kümpers P, Lukasz A, Dammann E, Verhagen W, Göhring G, et al. Shedding of the endothelial receptor tyrosine kinase Tie2 correlates with leukemic blast burden and outcome after allogeneic hematopoietic stem cell transplantation for AML. Ann Hematol. 2010;89:459-67 pubmed publisher
Serefhanoglu S, Goker H, Buyukasik Y, Turgut M, Sayinalp N, Haznedaroglu I, et al. Changes in vascular endothelial growth factor, angiopoietins, and Tie-2 levels with G-CSF stimulation in healthy donors. Ann Hematol. 2009;88:667-71 pubmed publisher
Cai J, Kehoe O, Smith G, Hykin P, Boulton M. The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy. Invest Ophthalmol Vis Sci. 2008;49:2163-71 pubmed publisher
Lee C, Tien H, Hu C, Chou W, Lin L. Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia. Br J Cancer. 2007;97:877-82 pubmed
Niedzwiecki S, Stepien T, Kopeć K, Kuzdak K, Komorowski J, Krupinski R, et al. Angiopoietin 1 (Ang-1), angiopoietin 2 (Ang-2) and Tie-2 (a receptor tyrosine kinase) concentrations in peripheral blood of patients with thyroid cancers. Cytokine. 2006;36:291-5 pubmed
Caine G, Ryan P, Lip G, Blann A. Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients. Cancer Lett. 2007;251:296-301 pubmed
Molskness T, Stouffer R, Burry K, Gorrill M, Lee D, Patton P. Circulating levels of total angiopoietin-2 and the soluble Tie-2 receptor in women during ovarian stimulation and early gestation. Fertil Steril. 2006;86:1531-3 pubmed
Quartarone E, Alonci A, Allegra A, Bellomo G, Calabro L, D Angelo A, et al. Differential levels of soluble angiopoietin-2 and Tie-2 in patients with haematological malignancies. Eur J Haematol. 2006;77:480-5 pubmed
Caine G, Stonelake P, Lip G, Blann A. Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer. Cancer Lett. 2007;248:131-6 pubmed
Tseng J, Hsu S, Ho E, Hsieh Y, Wen M, Chou M. Differential expression of angiopoietin-1, angiopoietin-2, and Tie receptors in placentas from pregnancies complicated by placenta accreta. Am J Obstet Gynecol. 2006;194:564-71 pubmed
Koutroubakis I, Xidakis C, Karmiris K, Sfiridaki A, Kandidaki E, Kouroumalis E. Potential role of soluble angiopoietin-2 and Tie-2 in patients with inflammatory bowel disease. Eur J Clin Invest. 2006;36:127-32 pubmed
Holland S, Powell M, Franci C, Chan E, Friera A, Atchison R, et al. Multiple roles for the receptor tyrosine kinase axl in tumor formation. Cancer Res. 2005;65:9294-303 pubmed
Mross K, Drevs J, Müller M, Medinger M, Marme D, Hennig J, et al. Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours. Eur J Cancer. 2005;41:1291-9 pubmed
Stahl A, Wenger A, Weber H, Stark G, Augustin H, Finkenzeller G. Bi-directional cell contact-dependent regulation of gene expression between endothelial cells and osteoblasts in a three-dimensional spheroidal coculture model. Biochem Biophys Res Commun. 2004;322:684-92 pubmed

product information

brand :

R&D Systems

master code :

DTE200

SKU :

DTE200

product name :

Human Tie-2 Quantikine ELISA Kit

description :

The Human Tie-2 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Tie-2 in cell culture supernates (100 ul), serum (10 ul), edta plasma (10 ul), heparin plasma (10 ul).

target :

Tie-2

category :

ELISAs

sizes available :

1 Kit

species :

Human

specificity :

Natural and recombinant human Tie-2

gene symbol :

TEK

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (100 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL)

elisaSensitivity :

0.066 ng/mL

elisaRange :

0.16 - 10 ng/mL

applications :

ELISA

USD :

615 USD

product details :

The Quantikine Human Tie-2 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Tie-2 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human Tie-2 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Tie-2 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Tie-2.

alt names :

angiopoietin-1 receptor, CD202B, CD202b antigen, EC 2.7.10, EC 2.7.10.1, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, TEK, TEK tyrosine kinase, endothelial, Tie2, TIE-2, TIE2CD202b, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, venous malformations, multiple cutaneous and mucosal, VMCM, VMCM1

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.