Human SOST/Sclerostin Quantikine ELISA Kit | R&D Systems DSST00 product information

product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human SOST/Sclerostin Quantikine ELISA Kit

catalog :

DSST00

quantity :

1 Kit

price :

655 USD

more info or order :

R&D Systems product webpage

citations: 12

Reference
Papagoras C, Tsiami S, Chrysanthopoulou A, Mitroulis I, Baraliakos X. Serum granulocyte-macrophage colony-stimulating factor (GM-CSF) is increased in patients with active radiographic axial spondyloarthritis and persists despite anti-TNF treatment. Arthritis Res Ther. 2022;24:195 pubmed publisher
Yu Y, Wang L, Ni S, Li D, Liu J, Chu H, et al. Targeting loop3 of sclerostin preserves its cardiovascular protective action and promotes bone formation. Nat Commun. 2022;13:4241 pubmed publisher
Rademacher J, Siderius M, Gellert L, Wink F, Verba M, Maas F, et al. Baseline serum biomarkers of inflammation, bone turnover and adipokines predict spinal radiographic progression in ankylosing spondylitis patients on TNF inhibitor therapy. Semin Arthritis Rheum. 2022;53:151974 pubmed publisher
Sylvawani M, Setyohadi B, Purnamasari D, Abdullah M, Kurniawan M. Comparison of insulin-like growth factor-1 and sclerostin levels between premenopausal women with and without diabetes mellitus. J Taibah Univ Med Sci. 2021;16:719-723 pubmed publisher
Nava Valdivia C, Ponce Guarneros J, Saldaña Cruz A, Corona Sánchez E, Ramirez Villafaña M, Perez Guerrero E, et al. Assessment of Serum sRANKL, sRANKL/OPG Ratio, and Other Bone Turnover Markers with the Estimated 10-Year Risk of Major and Hip Osteoporotic Fractures in Rheumatoid Arthritis: A Cross-Sectional Study. Biomed Res Int. 2021;2021:5567666 pubmed publisher
Kim J, Han W, Park T, Kim E, Bang I, Lee H, et al. Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains. Nat Commun. 2020;11:5357 pubmed publisher
Diani M, Perego S, Sansoni V, Bertino L, Gomarasca M, Faraldi M, et al. Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients. Int J Mol Sci. 2019;20: pubmed publisher
Kouvelioti R, Kurgan N, Falk B, Ward W, Josse A, Klentrou P. Response of Sclerostin and Bone Turnover Markers to High Intensity Interval Exercise in Young Women: Does Impact Matter?. Biomed Res Int. 2018;2018:4864952 pubmed publisher
Klentrou P, Angrish K, Awadia N, Kurgan N, Kouvelioti R, Falk B. Wnt Signaling-Related Osteokines at Rest and Following Plyometric Exercise in Prepubertal and Early Pubertal Boys and Girls. Pediatr Exerc Sci. 2018;30:457-465 pubmed publisher
Di Nisio A, De Toni L, Rocca M, Ghezzi M, Selice R, Taglialavoro G, et al. Negative Association Between Sclerostin and INSL3 in Isolated Human Osteocytes and in Klinefelter Syndrome: New Hints for Testis-Bone Crosstalk. J Clin Endocrinol Metab. 2018;103:2033-2041 pubmed publisher
Niu C, Lin S, Yuan L, Chen L, Yang C, Chung A, et al. Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL. BMC Musculoskelet Disord. 2017;18:61 pubmed publisher
Drake M, Khosla S. Hormonal and systemic regulation of sclerostin. Bone. 2017;96:8-17 pubmed publisher

image

image 1 :

Human SOST/Sclerostin ELISA Standard Curve

product information

master code :

DSST00

SKU :

DSST00

product name :

Human SOST/Sclerostin Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human SOST/Sclerostin Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human SOST/Sclerostin in cell culture supernates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul).

target :

SOST/Sclerostin

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human SOST

gene symbol :

SOST

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)

elisaSensitivity :

3.8 pg/mL

elisaRange :

31.30 - 2000 pg/mL

top caption :

Human SOST/Sclerostin ELISA Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human SOST immunoassay is a 4.5 hour solid-phase ELISA designed to measure SOST in human cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human SOST and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant human SOST. Results obtained using natural human SOST showed dose response curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural SOST.

alt names :

sclerostin, VBCHsclerosteosis

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.

more info or order :

R&D Systems product webpage