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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Serpin E1/PAI-1 Quantikine ELISA Kit
catalog :
DSE100
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 46
Reference
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Richards A, Khalil A, Friesen M, Whitfield T, Lungjangwa T, Gehrke L, et al. SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection. bioRxiv. 2023;: pubmed publisher
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Qin Y, Zhang J, Babapoor Farrokhran S, Applewhite B, Deshpande M, Megarity H, et al. PAI-1 is a vascular cell-specific HIF-2-dependent angiogenic factor that promotes retinal neovascularization in diabetic patients. Sci Adv. 2022;8:eabm1896 pubmed publisher
McAleavy M, Zhang Q, Ehmann P, Xu J, Wipperman M, Ajithdoss D, et al. The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients. Mol Cell Biol. 2022;42:e0046721 pubmed publisher
Cohen C, Le Goff O, Soysouvanh F, Vasseur F, Tanou M, Nguyen C, et al. Glomerular endothelial cell senescence drives age-related kidney disease through PAI-1. EMBO Mol Med. 2021;13:e14146 pubmed publisher
Cho S, Kim J, An H, Kim Y, Ahn E, Lee J, et al. Genetic Polymorphisms in miR-604A>G, miR-938G>A, miR-1302-3C>T and the Risk of Idiopathic Recurrent Pregnancy Loss. Int J Mol Sci. 2021;22: pubmed publisher
Voukalis C, Lip G, Shantsila E. Effects of antithrombotic drugs on the prothrombotic state in patients with atrial fibrillation: The west Birmingham atrial fibrillation project. Thromb Res. 2021;200:149-155 pubmed publisher
Wang Y, Chen H, Lo S, Chen Y, Huang Y, Hu S, et al. Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages. Cancers (Basel). 2020;12: pubmed publisher
Peng L, Ye Y, Mullikin H, Lin L, Kuhn C, Rahmeh M, et al. Expression of trophoblast derived prostaglandin E2 receptor 2 (EP2) is reduced in patients with recurrent miscarriage and EP2 regulates cell proliferation and expression of inflammatory cytokines. J Reprod Immunol. 2020;142:103210 pubmed publisher
Zmajkovicova K, Bauer Y, Menyhart K, Schnoebelen M, Freti D, Boucher M, et al. GPCR-induced YAP activation sensitizes fibroblasts to profibrotic activity of TGFβ1. PLoS ONE. 2020;15:e0228195 pubmed publisher
Hao N, Chiou T, Wu C, Lei Y, Liang P, Chao M, et al. Longitudinal Changes of PAI-1, MMP-2, and VEGF in Peritoneal Effluents and Their Associations with Peritoneal Small-Solute Transfer Rate in New Peritoneal Dialysis Patients. Biomed Res Int. 2019;2019:2152584 pubmed publisher
Ye Y, Kuhn C, Kösters M, Arnold G, Ishikawa Ankerhold H, Schulz C, et al. Anti α-enolase antibody is a novel autoimmune biomarker for unexplained recurrent miscarriages. EBioMedicine. 2019;: pubmed publisher
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Jakubowski M, Debski J, Szahidewicz Krupska E, Turek Jakubowska A, Gawryś J, Gawrys K, et al. Platelet Carbonic Anhydrase II, a Forgotten Enzyme, May Be Responsible for Aspirin Resistance. Oxid Med Cell Longev. 2017;2017:3132063 pubmed publisher
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Jiang H, Li X, Chen S, Lu N, Yue Y, Liang J, et al. Plasminogen Activator Inhibitor-1 in depression: Results from Animal and Clinical Studies. Sci Rep. 2016;6:30464 pubmed publisher
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product information
master code :
DSE100
SKU :
DSE100
product name :
Human Serpin E1/PAI-1 Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human Serpin E1/PAI-1 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Serpin E1/PAI-1 in cell culture supernates (50 ul), cell lysates (50 ul), edta plasma (50 ul), heparin plasma (50 ul), citrate plasma (50 ul), ctad plasma (50 ul).
target :
Serpin E1/PAI-1
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human Serpin E1
gene symbol :
SERPINE1
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Cell Lysates (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL), Citrate Plasma (50 uL), CTAD Plasma (50 uL)
elisaSensitivity :
0.142 ng/mL
elisaRange :
0.31 - 20 ng/mL
top caption :
Human Serpin E1/PAI-1 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human Serpin E1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Serpin E1 in cell culture supernates, cell lysates, and plasma. It contains Sf 21-expressed recombinant human Serpin E1 and has been shown to accurately quantitate the recombinant factor in its active and latent forms as well as in the vitronectin complexes. However, the kit does not detect recombinant human Serpin E1 in complexes with recombinant human uPA and recombinant human tPA. Results obtained using natural human Serpin E1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Serpin E1.
alt names :
Endothelial plasminogen activator inhibitor, Nexin, PAI1, PAI-1, PAI1PAI-1, PAISerpin E1, PLANH1, PLANH1plasminogen activator inhibitor 1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.