Human TNF RII/TNFRSF1B Quantikine ELISA Kit | R&D Systems DRT200 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human TNF RII/TNFRSF1B Quantikine ELISA Kit

catalog :

DRT200

quantity :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

price :

655 USD

citations: 76

Reference
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Cantón Habas V, Carrera González M, Moreno Casbas M, Quesada Gómez J, Rich Ruiz M. Correlation between biomarkers of pain in saliva and PAINAD scale in elderly people with cognitive impairment and inability to communicate: descriptive study protocol. BMJ Open. 2019;9:e032927 pubmed publisher
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Yogasundaram H, Nikhanj A, Putko B, Boutin M, Jain Ghai S, Khan A, et al. Elevated Inflammatory Plasma Biomarkers in Patients With Fabry Disease: A Critical Link to Heart Failure With Preserved Ejection Fraction. J Am Heart Assoc. 2018;7:e009098 pubmed publisher
Babic A, Schnure N, Neupane N, Zaman M, Rifai N, Welch M, et al. Plasma inflammatory cytokines and survival of pancreatic cancer patients. Clin Transl Gastroenterol. 2018;9:145 pubmed publisher
Kudo N, Yamamori H, Ishima T, Nemoto K, Yasuda Y, Fujimoto M, et al. Plasma Levels of Soluble Tumor Necrosis Factor Receptor 2 (sTNFR2) Are Associated with Hippocampal Volume and Cognitive Performance in Patients with Schizophrenia. Int J Neuropsychopharmacol. 2018;21:631-639 pubmed publisher
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Gohda T, Maruyama S, Kamei N, Yamaguchi S, Shibata T, Murakoshi M, et al. Circulating TNF Receptors 1 and 2 Predict Mortality in Patients with End-stage Renal Disease Undergoing Dialysis. Sci Rep. 2017;7:43520 pubmed publisher
Williams E, Baines K, Berthon B, Wood L. Effects of an Encapsulated Fruit and Vegetable Juice Concentrate on Obesity-Induced Systemic Inflammation: A Randomised Controlled Trial. Nutrients. 2017;9: pubmed publisher
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Kulkarni M, Bowman E, Gabriel J, Amburgy T, Mayne E, Zidar D, et al. Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection. Open Forum Infect Dis. 2016;3:ofw224 pubmed publisher
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Sobas E, Reinoso R, Cuadrado Asensio R, Fernandez I, Maldonado M, Pastor J. Reliability of Potential Pain Biomarkers in the Saliva of Healthy Subjects: Inter-Individual Differences and Intersession Variability. PLoS ONE. 2016;11:e0166976 pubmed publisher
Eng G, Bouchelouche P, Bartels E, Bliddal H, Bendtzen K, Stoltenberg M. Anti-Drug Antibodies, Drug Levels, Interleukin-6 and Soluble TNF Receptors in Rheumatoid Arthritis Patients during the First 6 Months of Treatment with Adalimumab or Infliximab: A Descriptive Cohort Study. PLoS ONE. 2016;11:e0162316 pubmed publisher
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Cauley J, Barbour K, Harrison S, Cloonan Y, Danielson M, Ensrud K, et al. Inflammatory Markers and the Risk of Hip and Vertebral Fractures in Men: the Osteoporotic Fractures in Men (MrOS). J Bone Miner Res. 2016;31:2129-2138 pubmed publisher
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Ouyang S, Li W, Liu Z, Li Y, Li S, Wu J. Association between serum soluble tumor necrosis factor-? receptors and early childhood obesity. Endocr J. 2016;63:581-7 pubmed publisher
Ghislain M, Bastard J, Meyer L, Capeau J, Fellahi S, GÃ©rard L, et al. Late Antiretroviral Therapy (ART) Initiation Is Associated with Long-Term Persistence of Systemic Inflammation and Metabolic Abnormalities. PLoS ONE. 2015;10:e0144317 pubmed publisher
Hayslip J, Dressler E, Weiss H, Taylor T, Chambers M, Noel T, et al. Plasma TNF-Î± and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna-A Randomized, Cross-Over Clinical Study. PLoS ONE. 2015;10:e0124988 pubmed publisher
Sonoda Y, Gohda T, Suzuki Y, Omote K, Ishizaka M, Matsuoka J, et al. Circulating TNF receptors 1 and 2 are associated with the severity of renal interstitial fibrosis in IgA nephropathy. PLoS ONE. 2015;10:e0122212 pubmed publisher
Duvillard L, Ortega Deballon P, Bourredjem A, Scherrer M, Mantion G, Delhorme J, et al. A case-control study of pre-operative levels of serum neutrophil gelatinase-associated lipocalin and other potential inflammatory markers in colorectal cancer. BMC Cancer. 2014;14:912 pubmed publisher
Putko B, Wang Z, Lo J, Anderson T, Becher H, Dyck J, et al. Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology. PLoS ONE. 2014;9:e99495 pubmed publisher
Skupien J, Warram J, Niewczas M, Gohda T, Malecki M, Mychaleckyj J, et al. Synergism between circulating tumor necrosis factor receptor 2 and HbA(1c) in determining renal decline during 5-18 years of follow-up in patients with type 1 diabetes and proteinuria. Diabetes Care. 2014;37:2601-8 pubmed publisher
Harder Lauridsen N, Krogh Madsen R, Holst J, Plomgaard P, Leick L, Pedersen B, et al. Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes. Am J Physiol Endocrinol Metab. 2014;306:E769-78 pubmed publisher
Shimizu M, Yachie A. Compensated inflammation in systemic juvenile idiopathic arthritis: role of alternatively activated macrophages. Cytokine. 2012;60:226-32 pubmed publisher
Grote V, Kaaks R, Nieters A, Tjønneland A, Halkjær J, Overvad K, et al. Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort. Br J Cancer. 2012;106:1866-74 pubmed publisher
Barbour K, Boudreau R, Danielson M, Youk A, Wactawski Wende J, Greep N, et al. Inflammatory markers and the risk of hip fracture: the Women's Health Initiative. J Bone Miner Res. 2012;27:1167-76 pubmed publisher
Chiang J, Eisenberger N, Seeman T, Taylor S. Negative and competitive social interactions are related to heightened proinflammatory cytokine activity. Proc Natl Acad Sci U S A. 2012;109:1878-82 pubmed publisher
Jiang H, Hampel H, Prvulovic D, Wallin A, Blennow K, Li R, et al. Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease. Mol Neurodegener. 2011;6:69 pubmed publisher
Hatzistilianou M, Rekliti A, Athanassiadou F, Catriu D. Procalcitonin as an early marker of bacterial infection in neutropenic febrile children with acute lymphoblastic leukemia. Inflamm Res. 2010;59:339-47 pubmed publisher
Karlson E, Chibnik L, Tworoger S, Lee I, Buring J, Shadick N, et al. Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies. Arthritis Rheum. 2009;60:641-52 pubmed publisher
Gombos T, Förhécz Z, Pozsonyi Z, Wallentin S, Papassotiriou J, Kunde J, et al. Adrenomedullin and endothelin-1 are related to inflammation in chronic heart failure. Inflamm Res. 2009;58:298-305 pubmed publisher
Murabito J, Keyes M, Guo C, Keaney J, Vasan R, D Agostino R, et al. Cross-sectional relations of multiple inflammatory biomarkers to peripheral arterial disease: The Framingham Offspring Study. Atherosclerosis. 2009;203:509-14 pubmed publisher
Master S, Amodio D, Stanton A, Yee C, Hilmert C, Taylor S. Neurobiological correlates of coping through emotional approach. Brain Behav Immun. 2009;23:27-35 pubmed publisher
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Cauley J, Danielson M, Boudreau R, Forrest K, Zmuda J, Pahor M, et al. Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study. J Bone Miner Res. 2007;22:1088-95 pubmed
Corvino C, Mamoni R, Fagundes G, Blotta M. Serum interleukin-18 and soluble tumour necrosis factor receptor 2 are associated with disease severity in patients with paracoccidioidomycosis. Clin Exp Immunol. 2007;147:483-90 pubmed
Tellier E, Canault M, Rebsomen L, Bonardo B, Juhan Vague I, Nalbone G, et al. The shedding activity of ADAM17 is sequestered in lipid rafts. Exp Cell Res. 2006;312:3969-80 pubmed
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Parissis J, Adamopoulos S, Karatzas D, Paraskevaidis J, Livanis E, Kremastinos D. Growth hormone-induced reduction of soluble apoptosis mediators is associated with reverse cardiac remodelling and improvement of exercise capacity in patients with idiopathic dilated cardiomyopathy. Eur J Cardiovasc Prev Rehabil. 2005;12:164-8 pubmed
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product information

master code :

DRT200

SKU :

DRT200

product name :

Human TNF RII/TNFRSF1B Quantikine ELISA Kit

unit size :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

description :

The Human TNF RII/TNFRSF1B Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human TNF RII/TNFRSF1B in cell culture supernates (200 ul), serum (20 ul), edta plasma (20 ul), heparin plasma (20 ul), citrate plasma (20 ul), urine (20 ul).

target :

TNF RII/TNFRSF1B

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human sTNF RII

gene symbol :

TNFRSF1B

kit type :

Solid Phase Sandwich ELISA

assay length :

3.5 hours or 4.5 hours

elisaSampleTypes :

Cell Culture Supernates (200 uL), Serum (20 uL), EDTA Plasma (20 uL), Heparin Plasma (20 uL), Citrate Plasma (20 uL), Urine (20 uL)

elisaSensitivity :

2.3 pg/mL

elisaRange :

7.80 - 500 pg/mL

top caption :

Human TNF RII/TNFRSF1B ELISA Cell Culture Supernate/Urine Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human sTNF RII Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure human sTNF RII in cell culture supernates, serum, plasma, or urine. It contains E. coli -expressed recombinant human sTNF RII as well as antibodies raised against this polypeptide. The recombinant protein represents the non-glycosylated, N-terminal methionyl form of the naturally occurring human soluble Type II receptor for TNF, minus 53 amino acids from the proline-rich region of the protein just exterior to the transmembrane domain, with an apparent molecular weight of approximately 19.8 kDa. This immunoassay has been shown to accurately quantitate the recombinant soluble sTNF RII. Results obtained using natural sTNF RII showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural sTNF RII. Since the measurement of human sTNF RII by this immunoassay is insensitive to added TNF-alpha or TNF-beta, it is probable that this measurement corresponds to the total amount of the soluble receptor present in samples, (i.e. the total amount of free receptor plus the total amount of receptor bound to TNF).

alt names :

CD120b, CD120b antigen, Etanercept, p75 TNF receptor, p75TBPII, p75TNFR, soluble TNFR1B variant 1, TNFBRp80 TNF-alpha receptor, TNF-R2, TNFR2TNFR1B, TNF-R75, TNFR80, TNFRII, TNF-RII, TNF-R-II, TNFR-II, TNFRSF1B, tumor necrosis factor beta receptor, tumor necrosis factor binding protein 2, Tumor necrosis factor receptor 2, tumor necrosis factor receptor superfamily member 1B, tumor necrosis factor receptor superfamily, member 1B, Tumor necrosis factor receptor type II

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.