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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human TNF RI/TNFRSF1A Quantikine ELISA Kit
catalog :
DRT100
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 86
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Morales T, Stamper C, Brenner L. High molar ratios of tumor necrosis factor α (TNF α) soluble receptors I and II to the TNF ligand in human plasma from male veterans with comorbid posttraumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI). Eur J Psychiatry. 2023;37:141-148 pubmed publisher
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Takao T, Yanagisawa H, Suka M, Yoshida Y, Onishi Y, Tahara T, et al. Synergistic association of the copper/zinc ratio under inflammatory conditions with diabetic kidney disease in patients with type 2 diabetes: The Asahi Diabetes Complications Study. J Diabetes Investig. 2022;13:299-307 pubmed publisher
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Hassan L, Medenwald D, Tiller D, Kluttig A, Ludwig Kraus B, Kraus F, et al. The association between change of soluble tumor necrosis factor receptor R1 (sTNF-R1) measurements and cardiovascular and all-cause mortality-Results from the population-based (Cardiovascular Disease, Living and Ageing in Halle) CARLA study 2002-2016. PLoS ONE. 2020;15:e0241213 pubmed publisher
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Cauley J, Kassem A, Lane N, Thorson S. Prevalent peripheral arterial disease and inflammatory burden. BMC Geriatr. 2016;16:213 pubmed
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Eng G, Bouchelouche P, Bartels E, Bliddal H, Bendtzen K, Stoltenberg M. Anti-Drug Antibodies, Drug Levels, Interleukin-6 and Soluble TNF Receptors in Rheumatoid Arthritis Patients during the First 6 Months of Treatment with Adalimumab or Infliximab: A Descriptive Cohort Study. PLoS ONE. 2016;11:e0162316 pubmed publisher
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Putko B, Wang Z, Lo J, Anderson T, Becher H, Dyck J, et al. Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology. PLoS ONE. 2014;9:e99495 pubmed publisher
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Wong J, Muthuswamy R, Bartlett D, Kalinski P. IL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients. Oncoimmunology. 2013;2:e26245 pubmed
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Denollet J, Vrints C, Conraads V. Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure. Brain Behav Immun. 2008;22:736-43 pubmed
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Canault M, Leroyer A, Peiretti F, Leseche G, Tedgui A, Bonardo B, et al. Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1. Am J Pathol. 2007;171:1713-23 pubmed
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Kissel C, Lehmann R, Assmus B, Aicher A, Honold J, Fischer Rasokat U, et al. Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure. J Am Coll Cardiol. 2007;49:2341-9 pubmed
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Doucet M, Russell A, Leger B, Debigare R, Joanisse D, Caron M, et al. Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007;176:261-9 pubmed
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Cauley J, Danielson M, Boudreau R, Forrest K, Zmuda J, Pahor M, et al. Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study. J Bone Miner Res. 2007;22:1088-95 pubmed
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Corvino C, Mamoni R, Fagundes G, Blotta M. Serum interleukin-18 and soluble tumour necrosis factor receptor 2 are associated with disease severity in patients with paracoccidioidomycosis. Clin Exp Immunol. 2007;147:483-90 pubmed
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Tellier E, Canault M, Rebsomen L, Bonardo B, Juhan Vague I, Nalbone G, et al. The shedding activity of ADAM17 is sequestered in lipid rafts. Exp Cell Res. 2006;312:3969-80 pubmed
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Lecube A, Hernandez C, Genesca J, Simo R. Proinflammatory cytokines, insulin resistance, and insulin secretion in chronic hepatitis C patients: A case-control study. Diabetes Care. 2006;29:1096-101 pubmed
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D Osualdo A, Ferlito F, Prigione I, Obici L, Meini A, Zulian F, et al. Neutrophils from patients with TNFRSF1A mutations display resistance to tumor necrosis factor-induced apoptosis: pathogenetic and clinical implications. Arthritis Rheum. 2006;54:998-1008 pubmed
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Bouchama A, Ollivier V, Roberts G, Al Mohanna F, de Prost D, Eldali A, et al. Experimental heatstroke in baboon: analysis of the systemic inflammatory response. Shock. 2005;24:332-5 pubmed
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Vergne Salle P, Leger D, Bertin P, Treves R, Beneytout J, Liagre B. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes. Cytokine. 2005;31:335-48 pubmed
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Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, et al. Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage. Crit Care Med. 2005;33:1359-64 pubmed
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Parissis J, Adamopoulos S, Karatzas D, Paraskevaidis J, Livanis E, Kremastinos D. Growth hormone-induced reduction of soluble apoptosis mediators is associated with reverse cardiac remodelling and improvement of exercise capacity in patients with idiopathic dilated cardiomyopathy. Eur J Cardiovasc Prev Rehabil. 2005;12:164-8 pubmed
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Kaneyama K, Segami N, Sun W, Sato J, Fujimura K. Levels of soluble cytokine factors in temporomandibular joint effusions seen on magnetic resonance images. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:411-8 pubmed
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Kaneyama K, Segami N, Sun W, Sato J, Fujimura K. Analysis of tumor necrosis factor-alpha, interleukin-6, interleukin-1beta, soluble tumor necrosis factor receptors I and II, interleukin-6 soluble receptor, interleukin-1 soluble receptor type II, interleukin-1 receptor antagonist, and protein in the. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:276-84 pubmed
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Lukashevich I, Tikhonov I, Rodas J, Zapata J, Yang Y, Djavani M, et al. Arenavirus-mediated liver pathology: acute lymphocytic choriomeningitis virus infection of rhesus macaques is characterized by high-level interleukin-6 expression and hepatocyte proliferation. J Virol. 2003;77:1727-37 pubmed
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product information
master code :
DRT100
SKU :
DRT100
product name :
Human TNF RI/TNFRSF1A Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human TNF RI/TNFRSF1A Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human TNF RI/TNFRSF1A in cell culture supernates (200 ul), serum (20 ul), edta plasma (20 ul), heparin plasma (20 ul), citrate plasma (20 ul), urine (20 ul).
target :
TNF RI/TNFRSF1A
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human sTNF RI
gene symbol :
TNFRSF1A
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (200 uL), Serum (20 uL), EDTA Plasma (20 uL), Heparin Plasma (20 uL), Citrate Plasma (20 uL), Urine (20 uL)
elisaSensitivity :
1.2 pg/mL
elisaRange :
7.80 - 500 pg/mL
top caption :
Human TNF RI/TNFRSF1A ELISA Calibrator Diluent RD5-5 Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human sTNF RI Immunoassay is a 4.5 hour solid phase ELISA designed to measure sTNF RI in cell culture supernates, serum, plasma, and urine. It contains E. coli -expressed recombinant human sTNF RI, as well as antibodies raised against this polypeptide. The recombinant protein represents the non-glycosylated, N-terminal methionyl form of the naturally occurring human soluble Type I receptor for TNF with an apparent molecular weight of approximately 18.6 kDa. This immunoassay has been shown to accurately quantitate the recombinant sTNF RI. Results obtained on samples containing natural sTNF RI showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural sTNF RI. Since the measurement of human sTNF RI by this immunoassay is relatively insensitive to added TNF-alpha or TNF-beta, it is probable that this measurement corresponds to the total amount of the soluble receptor present in samples (i.e. the total amount of free receptor plus the total amount of receptor bound to TNF).
alt names :
CD120a, CD120a antigen, FPF, p55, p55-R, p60, TNFARMGC19588, TNF-R, TNF-R1, TNFR1TBP1, TNFR55, TNF-R55, TNFR60, TNFRI, TNF-RI, TNF-R-I, TNFR-I, TNFRSF1A, tumor necrosis factor binding protein 1, Tumor necrosis factor receptor 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor receptor superfamily, member 1A, tumor necrosis factor receptor type 1, Tumor necrosis factor receptor type I, tumor necrosis factor-alpha receptor
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
questions and comments
