This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human CD25/IL-2R alpha Quantikine ELISA Kit
catalog :
DR2A00
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 36
Reference
Ernzen K, Melvin C, Yu L, Phelps C, Niewiesk S, Green P, et al. The PRMT5 inhibitor EPZ015666 is effective against HTLV-1-transformed T-cell lines in vitro and in vivo. Front Microbiol. 2023;14:1101544 pubmed publisher
Trujillo Rodriguez M, Mu xf1 oz Muela E, Serna Gallego A, Praena Fern xe1 ndez J, P xe9 rez G xf3 mez A, Gasca Capote C, et al. Clinical, laboratory data and inflammatory biomarkers at baseline as early discharge predictors in hospitalized SARS-CoV-2 infected patients. PLoS ONE. 2022;17:e0269875 pubmed publisher
Rosen D, Murphy E, Gejman R, Capili A, Friedlander R, Rand S, et al. Cytokine response over the course of COVID-19 infection in pregnant women. Cytokine. 2022;154:155894 pubmed publisher
Buhelt S, Søndergaard H, Mahler M, Cobanovic S, Börnsen L, Ammitzbøll C, et al. Biomarkers of systemic inflammation, soluble IL-2Rα and the multiple sclerosis-associated IL2RA SNP rs2104286 in healthy subjects and multiple sclerosis patients. Mult Scler Relat Disord. 2021;54:103140 pubmed publisher
Xu S, Li H, Qiao P, Xu G, Zhao D, Lin X, et al. Neonatal hand, foot, and mouth disease due to coxsackievirus A6 in Shanghai. BMC Pediatr. 2020;20:364 pubmed publisher
Herrera M, Vera C, Keynan Y, Rueda Z. Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review. J Immunol Res. 2020;2020:8074183 pubmed publisher
Gayden T, Sepulveda F, Khuong Quang D, Pratt J, Valera E, Garrigue A, et al. Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome. Nat Genet. 2018;50:1650-1657 pubmed publisher
Ribba B, Boetsch C, Nayak T, Grimm H, Charo J, Evers S, et al. Prediction of the Optimal Dosing Regimen Using a Mathematical Model of Tumor Uptake for Immunocytokine-Based Cancer Immunotherapy. Clin Cancer Res. 2018;24:3325-3333 pubmed publisher
de Armas L, Pallikkuth S, George V, Rinaldi S, Pahwa R, Arheart K, et al. Reevaluation of immune activation in the era of cART and an aging HIV-infected population. JCI Insight. 2017;2: pubmed publisher
Ellis E, Sharp T, Perez Padilla J, González L, Poole Smith B, Lebo E, et al. Incidence and Risk Factors for Developing Dengue-Associated Hemophagocytic Lymphohistiocytosis in Puerto Rico, 2008 - 2013. PLoS Negl Trop Dis. 2016;10:e0004939 pubmed publisher
Aziz N, Detels R, Quint J, Li Q, Gjertson D, Butch A. Stability of cytokines, chemokines and soluble activation markers in unprocessed blood stored under different conditions. Cytokine. 2016;84:17-24 pubmed publisher
Koreth J, Kim H, Jones K, Lange P, Reynolds C, Chammas M, et al. Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease. Blood. 2016;128:130-7 pubmed publisher
Yu P, Petrus M, Ju W, Zhang M, Conlon K, Nakagawa M, et al. Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model. Leukemia. 2015;29:556-66 pubmed publisher
Marzec M, Halasa K, Liu X, Wang H, Cheng M, Baldwin D, et al. Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming. J Immunol. 2013;191:6200-7 pubmed publisher
Førsvoll J, Kristoffersen E, Oymar K. Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system. Pediatr Rheumatol Online J. 2013;11:38 pubmed publisher
Kassianos A, Hardy M, Ju X, Vijayan D, Ding Y, Vulink A, et al. Human CD1c (BDCA-1)+ myeloid dendritic cells secrete IL-10 and display an immuno-regulatory phenotype and function in response to Escherichia coli. Eur J Immunol. 2012;42:1512-22 pubmed publisher
Singh R, Zhang Y, Pastan I, Kreitman R. Synergistic antitumor activity of anti-CD25 recombinant immunotoxin LMB-2 with chemotherapy. Clin Cancer Res. 2012;18:152-60 pubmed publisher
Ravandi F, O Brien S, Jorgensen J, Pierce S, Faderl S, Ferrajoli A, et al. Phase 2 study of cladribine followed by rituximab in patients with hairy cell leukemia. Blood. 2011;118:3818-23 pubmed publisher
Savan R, McFarland A, Reynolds D, Feigenbaum L, Ramakrishnan K, Karwan M, et al. A novel role for IL-22R1 as a driver of inflammation. Blood. 2011;117:575-84 pubmed publisher
Schmidt H, Brown J, Mouritzen U, Selby P, Fode K, Svane I, et al. Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial. Clin Cancer Res. 2010;16:5312-9 pubmed publisher
Bachert C, Zhang N, Holtappels G, De Lobel L, Van Cauwenberge P, Liu S, et al. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J Allergy Clin Immunol. 2010;126:962-8, 968.e1-6 pubmed publisher
Ishii T, Ishida T, Utsunomiya A, Inagaki A, Yano H, Komatsu H, et al. Defucosylated humanized anti-CCR4 monoclonal antibody KW-0761 as a novel immunotherapeutic agent for adult T-cell leukemia/lymphoma. Clin Cancer Res. 2010;16:1520-31 pubmed publisher
Sadeghi M, Daniel V, Schnitzler P, Lahdou I, Naujokat C, Zeier M, et al. Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria. Transplantation. 2009;88:1109-16 pubmed publisher
Chen J, Zhang M, Ju W, Waldmann T. Effective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25. Blood. 2009;113:1287-93 pubmed publisher
Kabagambe E, Ordovas J, Tsai M, Borecki I, Hopkins P, Glasser S, et al. Smoking, inflammatory patterns and postprandial hypertriglyceridemia. Atherosclerosis. 2009;203:633-9 pubmed publisher
Sadeghi M, Süsal C, Daniel V, Naujokat C, Zimmermann R, Huth Kühne A, et al. Short communication: decreasing soluble CD30 and increasing IFN-gamma plasma levels are indicators of effective highly active antiretroviral therapy. AIDS Res Hum Retroviruses. 2007;23:886-90 pubmed
Davis I, Skrumsager B, Cebon J, Nicholaou T, Barlow J, Moller N, et al. An open-label, two-arm, phase I trial of recombinant human interleukin-21 in patients with metastatic melanoma. Clin Cancer Res. 2007;13:3630-6 pubmed
Cauley J, Danielson M, Boudreau R, Forrest K, Zmuda J, Pahor M, et al. Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study. J Bone Miner Res. 2007;22:1088-95 pubmed
Coupel S, Moreau A, Hamidou M, Horejsi V, Soulillou J, Charreau B. Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation. Blood. 2007;109:2806-14 pubmed
Zhang Z, Zhang M, Garmestani K, Talanov V, Plascjak P, Beck B, et al. Effective treatment of a murine model of adult T-cell leukemia using 211At-7G7/B6 and its combination with unmodified anti-Tac (daclizumab) directed toward CD25. Blood. 2006;108:1007-12 pubmed
Zhang M, Yao Z, Zhang Z, Garmestani K, Goldman C, Ravetch J, et al. Effective therapy for a murine model of human anaplastic large-cell lymphoma with the anti-CD30 monoclonal antibody, HeFi-1, does not require activating Fc receptors. Blood. 2006;108:705-10 pubmed
Zhang M, Zhang Z, Garmestani K, Goldman C, Ravetch J, Brechbiel M, et al. Activating Fc receptors are required for antitumor efficacy of the antibodies directed toward CD25 in a murine model of adult t-cell leukemia. Cancer Res. 2004;64:5825-9 pubmed
Xiao T, Fujita H, Saeki H, Mitsui H, Sugaya M, Tada Y, et al. Thymus and activation-regulated chemokine (TARC/CCL17) produced by mouse epidermal Langerhans cells is upregulated by TNF-alpha and IL-4 and downregulated by IFN-gamma. Cytokine. 2003;23:126-32 pubmed
Sedlaczek P, Frydecka I, Gabrys M, Van Dalen A, Einarsson R, Harłozińska A. Comparative analysis of CA125, tissue polypeptide specific antigen, and soluble interleukin-2 receptor alpha levels in sera, cyst, and ascitic fluids from patients with ovarian carcinoma. Cancer. 2002;95:1886-93 pubmed
Attanasio R, Brasky K, Robbins S, Jayashankar L, Nash R, Butler T. Age-related autoantibody production in a nonhuman primate model. Clin Exp Immunol. 2001;123:361-5 pubmed
von Kobyletzki G, Pieck C, Hoffmann K, Freitag M, Altmeyer P. Medium-dose UVA1 cold-light phototherapy in the treatment of severe atopic dermatitis. J Am Acad Dermatol. 1999;41:931-7 pubmed
product information
master code :
DR2A00
SKU :
DR2A00
product name :
Human CD25/IL-2R alpha Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human CD25/IL-2R alpha Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human CD25/IL-2R alpha in cell culture supernates (10 ul), serum (13 ul), edta plasma (13 ul), heparin plasma (13 ul).
target :
CD25/IL-2R alpha
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human IL-2 sR alpha
gene symbol :
IL2RA
kit type :
Solid Phase Sandwich ELISA
assay length :
3.5 hours
elisaSampleTypes :
Cell Culture Supernates (10 uL), Serum (13 uL), EDTA Plasma (13 uL), Heparin Plasma (13 uL)
elisaSensitivity :
10 pg/mL
elisaRange :
78.00 - 5000 pg/mL
top caption :
Human IL2RA ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human IL-2 sR alpha Immunoassay is a 3.5 hour solid phase ELISA designed to measure IL-2 sR alpha in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human IL-2 sR alpha and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural human IL-2 sR alpha showed linear curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-2 sR alpha.
alt names :
CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL2R, IL2R alpha, IL-2R subunit alpha, IL-2Ra, IL2RA, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.