Human IL-1 RII Quantikine ELISA Kit | R&D Systems DR1B00 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human IL-1 RII Quantikine ELISA Kit

catalog :

DR1B00

quantity :

1 Kit

price :

655 USD

citations: 16

Reference
Lin J, Li Q, Jin T, Wang J, Gong Y, Lv Q, et al. Cardiomyocyte IL-1R2 protects heart from ischemia/reperfusion injury by attenuating IL-17RA-mediated cardiomyocyte apoptosis. Cell Death Dis. 2022;13:90 pubmed publisher
Yuan M, Wang L, Huang H, Li Y, Zheng X, Shao Q, et al. IL-1R2 expression in human gastric cancer and its clinical significance. Biosci Rep. 2021;41: pubmed publisher
Tran T, Grievink H, Lipinska K, Kluft C, Burggraaf J, Moerland M, et al. Whole blood assay as a model for in vitro evaluation of inflammasome activation and subsequent caspase-mediated interleukin-1 beta release. PLoS ONE. 2019;14:e0214999 pubmed publisher
Pathak S, Goldofsky E, Vivas E, Bonagura V, Vambutas A. IL-1? is overexpressed and aberrantly regulated in corticosteroid nonresponders with autoimmune inner ear disease. J Immunol. 2011;186:1870-9 pubmed publisher
Harboe E, Tjensvoll A, Vefring H, Gøransson L, Kvaløy J, Omdal R. Fatigue in primary Sjögren's syndrome--a link to sickness behaviour in animals?. Brain Behav Immun. 2009;23:1104-8 pubmed publisher
Lachmann H, Lowe P, Felix S, Rordorf C, Leslie K, Madhoo S, et al. In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes. J Exp Med. 2009;206:1029-36 pubmed publisher
Ma Y, Visser L, Roelofsen H, de Vries M, Diepstra A, Van Imhoff G, et al. Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes. Blood. 2008;111:2339-46 pubmed
Wilson H, Varcoe R, Stokes L, Holland K, Francis S, Dower S, et al. P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells. Br J Pharmacol. 2007;151:115-27 pubmed
Lindberg C, Chromek M, Ahrengart L, Brauner A, Schultzberg M, Garlind A. Soluble interleukin-1 receptor type II, IL-18 and caspase-1 in mild cognitive impairment and severe Alzheimer's disease. Neurochem Int. 2005;46:551-7 pubmed
Kaneyama K, Segami N, Sun W, Sato J, Fujimura K. Levels of soluble cytokine factors in temporomandibular joint effusions seen on magnetic resonance images. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:411-8 pubmed
Tominaga K, Habu M, Sukedai M, Hirota Y, Takahashi T, Fukuda J. IL-1 beta, IL-1 receptor antagonist and soluble type II IL-1 receptor in synovial fluid of patients with temporomandibular disorders. Arch Oral Biol. 2004;49:493-9 pubmed
Brooks Asplund E, Tupper C, Daun J, Kenney W, Cannon J. Determinants of plasma leptin concentration in postmenopausal women. Mech Ageing Dev. 2004;125:117-9 pubmed
Bronge L, Wahlund L, Brauner A, Basun H, Garlind A. White matter lesions and soluble interleukin-1 receptor type II in CSF from demented and non-demented subjects. Neurochem Int. 2002;41:217-22 pubmed
Cubitt C, Lausch R, Oakes J. Synthesis of type II interleukin-1 receptors by human corneal epithelial cells but not by keratocytes. Invest Ophthalmol Vis Sci. 2001;42:701-4 pubmed
Attur M, Dave M, Clancy R, Patel I, Abramson S, Amin A. Functional genomic analysis in arthritis-affected cartilage: yin-yang regulation of inflammatory mediators by alpha 5 beta 1 and alpha V beta 3 integrins. J Immunol. 2000;164:2684-91 pubmed
Sunyer T, Lewis J, Collin Osdoby P, Osdoby P. Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells. J Clin Invest. 1999;103:1409-18 pubmed

product information

master code :

DR1B00

SKU :

DR1B00

product name :

Human IL-1 RII Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human IL-1 RII Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human IL-1 RII in cell culture supernates (100 ul), serum (10 ul), edta plasma (10 ul), heparin plasma (10 ul), citrate plasma (10 ul).

target :

IL-1 RII

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human IL-1 sRII

gene symbol :

IL1R2

kit type :

Solid Phase Sandwich ELISA

assay length :

3.5 hours

elisaSampleTypes :

Cell Culture Supernates (100 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Citrate Plasma (10 uL)

elisaSensitivity :

10 pg/mL

elisaRange :

31.20 - 2000 pg/mL

top caption :

Human IL-1 RII ELISA Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human IL-1 sRII Immunoassay is a 3.5 hour solid phase ELISA designed to measure IL-1 sRII in serum, plasma, and cell culture supernates. It contains insect cell-expressed recombinant human IL-1 sRII and has been shown to quantitate the recombinant factor accurately. Results obtained using natural IL-1 sRII showed linear curves that were parallel to the standard curves obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for natural IL-1 sRII. The presence of high levels of IL-1 beta ( 7.5 ng/mL) in samples has been found to produce some interference ( 10% change) when assaying samples containing IL-1 sRII in the mid-level range.

alt names :

beta, CD121b, CD121b antigen, IL-1 R beta, IL1R2, IL1RBCD121 antigen-like family member B, IL-1R-beta, IL1RII, IL-1RII, IL-1RT2, IL-1RT-2, interleukin 1 receptor, type II, Interleukin-1 receptor beta, MGC47725

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.