Human Progranulin Quantikine ELISA Kit | R&D Systems DPGRN0 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human Progranulin Quantikine ELISA Kit

catalog :

DPGRN0

quantity :

1 Kit

price :

655 USD

citations: 18

Reference
He Y, Kaya I, Shariatgorji R, Lundkvist J, Wahlberg L, Nilsson A, et al. Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents. Nat Commun. 2023;14:5804 pubmed publisher
T xf3 th N, M xfc ller V, Nagy T, Polivka L, Horv xe1 th P, Boh xe1 cs A, et al. Serum Progranulin Level Might Differentiate Non-IPF ILD from IPF. Int J Mol Sci. 2023;24: pubmed publisher
Gohda T, Murakoshi M, Suzuki Y, Hiki M, Naito T, Takahashi K, et al. Circulating tumor necrosis factor receptors are associated with mortality and disease severity in COVID-19 patients. PLoS ONE. 2022;17:e0275745 pubmed publisher
Raposo Lima C, Pereira I, Marques F, Morgado P. Elevated levels of neutrophil gelatinase-associated lipocalin among OCD patients: an exploratory study. BMC Psychiatry. 2021;21:272 pubmed publisher
Samejima T, Nagamatsu T, Akiba N, Fujii T, Sayama S, Kawana K, et al. Secretory leukocyte protease inhibitor and progranulin as possible regulators of cervical remodeling in pregnancy. J Reprod Immunol. 2021;143:103241 pubmed publisher
Nguyen A, Malmstrom T, Niehoff M, Aziz A, Miller D, Morley J. Serum progranulin levels are associated with frailty in middle-aged individuals. PLoS ONE. 2020;15:e0238877 pubmed publisher
Rao L, Song Z, Yu X, Tu Q, He Y, Luo Y, et al. Progranulin as a novel biomarker in diagnosis of early-onset neonatal sepsis. Cytokine. 2020;128:155000 pubmed publisher
Schmitz K, Wilken Schmitz A, Vasic V, Brunkhorst R, Schmidt M, Tegeder I. Progranulin deficiency confers resistance to autoimmune encephalomyelitis in mice. Cell Mol Immunol. 2019;: pubmed publisher
Nicoletto B, Sarmento R, Pedrollo E, Krolikowski T, Canani L. Association between progranulin serum levels and dietary intake. PLoS ONE. 2018;13:e0202149 pubmed publisher
Choi G, Trinh H, Yang E, Ye Y, Shin Y, Kim S, et al. Role of clusterin/progranulin in toluene diisocyanate-induced occupational asthma. Exp Mol Med. 2018;50:58 pubmed publisher
Grewal R, Haghighi M, Huang S, Smith A, Cao C, Lin X, et al. Identifying biomarkers of dementia prevalent among amnestic mild cognitively impaired ethnic female patients. Alzheimers Res Ther. 2016;8:43 pubmed
Sinfield J, Das A, O Regan D, Ball S, Porter K, Turner N. p38 MAPK alpha mediates cytokine-induced IL-6 and MMP-3 expression in human cardiac fibroblasts. Biochem Biophys Res Commun. 2013;430:419-24 pubmed publisher
Richter J, Focke D, Ebert T, Kovacs P, Bachmann A, Lossner U, et al. Serum levels of the adipokine progranulin depend on renal function. Diabetes Care. 2013;36:410-4 pubmed publisher
Gass J, Lee W, Cook C, Finch N, Stetler C, Jansen West K, et al. Progranulin regulates neuronal outgrowth independent of sortilin. Mol Neurodegener. 2012;7:33 pubmed publisher
Suh H, Choi N, Tarassishin L, Lee S. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12). PLoS ONE. 2012;7:e35115 pubmed publisher
Al Ayadhi L, Mostafa G. Low plasma progranulin levels in children with autism. J Neuroinflammation. 2011;8:111 pubmed publisher
Diamandis E, Goodglick L, Planque C, Thornquist M. Pentraxin-3 is a novel biomarker of lung carcinoma. Clin Cancer Res. 2011;17:2395-9 pubmed publisher
Carrasquillo M, Nicholson A, Finch N, Gibbs J, Baker M, Rutherford N, et al. Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma. Am J Hum Genet. 2010;87:890-7 pubmed publisher

product information

master code :

DPGRN0

SKU :

DPGRN0

product name :

Human Progranulin Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human Progranulin Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Progranulin/PGRN in cell culture supernates (50 ul), serum (10 ul), edta plasma (10 ul), heparin plasma (10 ul), saliva (10 ul), urine (25 ul), human milk (10 ul).

target :

Progranulin/PGRN

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human Progranulin. Trypsin and Elastase cleaved Progranulin show reduced recognition in this assay, demonstrating specificity for Progranulin.

gene symbol :

GRN

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Saliva (10 uL), Urine (25 uL), Human Milk (10 uL)

elisaSensitivity :

0.54 ng/mL

elisaRange :

1.56 - 100 ng/mL

top caption :

Human Progranulin/PGRN ELISA Serum/Plasma/Urine Human Milk Standard Curve

applications :

ELISA

extended description :

Not Available in Europe

USD :

655 USD

product details :

The Quantikine Human Progranulin immunoassay is a 4.5 hour solid phase ELISA designed to measure Progranulin in cell culture supernates, serum, plasma, saliva, urine, and human milk. It contains NS0-expressed recombinant human Progranulin and has been shown to accurately quantitate the recombinant factor. Results obtained using natural Progranulin showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Progranulin.

alt names :

Acrogranin, CLN11, GEP, GP88, granulin precursor, GRN, PCDGF, PEPI, PGRN, Proepithelin

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.