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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Endoglin/CD105 Quantikine ELISA Kit
catalog :
DNDG00
quantity :
1 Kit
price :
655 USD
citations: 42
Reference
Duan L, Ma Y, Reisch B, Hadrovic E, Mach P, Kimmig R, et al. Alteration in sB7-H4 Serum Levels and Placental Biomarker Expression after Therapeutic Plasma Exchange in Early-Onset Preeclampsia Patients. Int J Mol Sci. 2024;25: pubmed publisher
Pintye D, Sziva R, Mastyugin M, Young B, Jacas S, T xf6 r xf6 k M, et al. A Novel Dual-Function Redox Modulator Relieves Oxidative Stress and Anti-Angiogenic Response in Placental Villus Explant Exposed to Hypoxia-Relevance for Preeclampsia Therapy. Biology (Basel). 2023;12: pubmed publisher
Yang Z, Jia X, Deng Q, Luo M, Hou Y, Yue J, et al. Human umbilical cord mesenchymal stem cell-derived extracellular vesicles loaded with TFCP2 activate Wnt/β-catenin signaling to alleviate preeclampsia. Int Immunopharmacol. 2023;115:109732 pubmed publisher
Dymara Konopka W, Laskowska M, Grywalska E, Hymos A, B x142 a x17c ewicz A, Leszczy x144 ska Gorzelak B. Similar Pro- and Antiangiogenic Profiles Close to Delivery in Different Clinical Presentations of Two Pregnancy Syndromes: Preeclampsia and Fetal Growth Restriction. Int J Mol Sci. 2023;24: pubmed publisher
Haarmann A, Vollmuth C, Kollikowski A, Heuschmann P, Pham M, Stoll G, et al. Vasoactive Soluble Endoglin: A Novel Biomarker Indicative of Reperfusion after Cerebral Large-Vessel Occlusion. Cells. 2023;12: pubmed publisher
Ryu G, Kim Y, Lee K, Choi S, Hong S, Jung Y, et al. Obstructive Sleep Apnea Is Associated With Late-Onset Preeclampsia in Overweight Pregnant Women in Korea. J Korean Med Sci. 2023;38:e8 pubmed publisher
Abascal Saiz A, Duque Alcorta M, Fioravantti V, Antol xed n E, Fuente Luelmo E, Haro M, et al. The Relationship between Angiogenic Factors and Energy Metabolism in Preeclampsia. Nutrients. 2022;14: pubmed publisher
Anto E, Coall D, Asiamah E, Afriyie O, Addai Mensah O, Wiafe Y, et al. Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia. PLoS ONE. 2022;17:e0265717 pubmed publisher
Nejmanov xe1 I, Vitverov xe1 B, Eissazadeh S, Tripsk xe1 K, Igreja Sa I, Hy x161 pler R, et al. High Soluble Endoglin Levels Affect Aortic Vascular Function during Mice Aging. J Cardiovasc Dev Dis. 2021;8: pubmed publisher
Ruiz Llorente L, Vega M, Fernandez F, Langa C, Morrell N, Upton P, et al. Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein. Int J Mol Sci. 2021;22: pubmed publisher
Pérez Roque L, Núñez Gómez E, Rodriguez Barbero A, Bernabeu C, Lopez Novoa J, Pericacho M. Pregnancy-Induced High Plasma Levels of Soluble Endoglin in Mice Lead to Preeclampsia Symptoms and Placental Abnormalities. Int J Mol Sci. 2020;22: pubmed publisher
Kim S, Park M, Kim J, Kim T, Hwang J, Ha K, et al. Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia. Cells. 2020;9: pubmed publisher
Polster S, Sharma A, Tanes C, Tang A, Mericko P, Cao Y, et al. Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma. Nat Commun. 2020;11:2659 pubmed publisher
Wilson D, Howard M, Fung A, O Donoghue F, Barnes M, Lappas M, et al. Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy. PLoS ONE. 2020;15:e0232287 pubmed publisher
Gallardo Vara E, Gamella Pozuelo L, Pérez Roque L, Bartha J, García Palmero I, Casal J, et al. Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4. Cells. 2020;9: pubmed publisher
Rahman R, Murthi P, Singh H, Gurungsinghe S, Leaw B, Mockler J, et al. Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia. Int J Mol Sci. 2020;21: pubmed publisher
Aristorena M, Gallardo Vara E, Vicen M, de Las Casas Engel M, Ojeda Fernandez L, Nieto C, et al. MMP-12, Secreted by Pro-Inflammatory Macrophages, Targets Endoglin in Human Macrophages and Endothelial Cells. Int J Mol Sci. 2019;20: pubmed publisher
Unger H, Hansa A, Buffet C, Hasang W, Teo A, Randall L, et al. Sulphadoxine-pyrimethamine plus azithromycin may improve birth outcomes through impacts on inflammation and placental angiogenesis independent of malarial infection. Sci Rep. 2019;9:2260 pubmed publisher
Li H, Yao J, Chang X, Wu J, Duan T, Wang K. LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia. Reproduction. 2018;155:297-306 pubmed publisher
Ruiz Remolina L, Ollauri Ibáñez C, Pérez Roque L, Núñez Gómez E, Perez Barriocanal F, Lopez Novoa J, et al. Circulating soluble endoglin modifies the inflammatory response in mice. PLoS ONE. 2017;12:e0188204 pubmed publisher
O Brien M, Baczyk D, Kingdom J. Endothelial Dysfunction in Severe Preeclampsia is Mediated by Soluble Factors, Rather than Extracellular Vesicles. Sci Rep. 2017;7:5887 pubmed publisher
Blaha V, Blaha M, Lanska M, Solichova D, Kujovska Krcmova L, Havel E, et al. Lipoprotein apheresis in the treatment of dyslipidaemia - the Czech Republic experience. Physiol Res. 2017;66:S91-S100 pubmed
Saita E, Miura K, Suzuki Sugihara N, Miyata K, Ikemura N, Ohmori R, et al. Plasma Soluble Endoglin Levels Are Inversely Associated With the Severity of Coronary Atherosclerosis-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:49-52 pubmed publisher
Weel I, Baergen R, Romão Veiga M, Borges V, Ribeiro V, Witkin S, et al. Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia. PLoS ONE. 2016;11:e0157584 pubmed publisher
Nemeckova I, Serwadczak A, Oujo B, Ježková K, Rathouska J, Fikrová P, et al. High soluble endoglin levels do not induce endothelial dysfunction in mouse aorta. PLoS ONE. 2015;10:e0119665 pubmed publisher
White W, Garrett A, Craici I, Wagner S, Fitz Gibbon P, Butters K, et al. Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury. PLoS ONE. 2014;9:e92693 pubmed publisher
Rana S, Cerdeira A, Wenger J, Salahuddin S, Lim K, Ralston S, et al. Plasma concentrations of soluble endoglin versus standard evaluation in patients with suspected preeclampsia. PLoS ONE. 2012;7:e48259 pubmed publisher
Widemann B, Kim A, Fox E, Baruchel S, Adamson P, Ingle A, et al. A phase I trial and pharmacokinetic study of sorafenib in children with refractory solid tumors or leukemias: a Children's Oncology Group Phase I Consortium report. Clin Cancer Res. 2012;18:6011-22 pubmed publisher
Kaitu u Lino T, Palmer K, Tuohey L, Ye L, Tong S. MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin. PLoS ONE. 2012;7:e39864 pubmed publisher
Silver K, Conroy A, Leke R, Leke R, Gwanmesia P, Molyneux M, et al. Circulating soluble endoglin levels in pregnant women in Cameroon and Malawi--associations with placental malaria and fetal growth restriction. PLoS ONE. 2011;6:e24985 pubmed publisher
Landt S, Mordelt K, Schwidde I, Barinoff J, Korlach S, Stöblen F, et al. Prognostic significance of the angiogenic factors angiogenin, endoglin and endostatin in cervical cancer. Anticancer Res. 2011;31:2651-5 pubmed
DuBois S, Shusterman S, Ingle A, Ahern C, Reid J, Wu B, et al. Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study. Clin Cancer Res. 2011;17:5113-22 pubmed publisher
Jeyabalan A, Powers R, Clifton R, Van Dorsten P, Hauth J, Klebanoff M, et al. Effect of smoking on circulating angiogenic factors in high risk pregnancies. PLoS ONE. 2010;5:e13270 pubmed publisher
Powers R, Jeyabalan A, Clifton R, Van Dorsten P, Hauth J, Klebanoff M, et al. Soluble fms-Like tyrosine kinase 1 (sFlt1), endoglin and placental growth factor (PlGF) in preeclampsia among high risk pregnancies. PLoS ONE. 2010;5:e13263 pubmed publisher
Santner Nanan B, Peek M, Khanam R, Richarts L, Zhu E, Fazekas de St Groth B, et al. Systemic increase in the ratio between Foxp3+ and IL-17-producing CD4+ T cells in healthy pregnancy but not in preeclampsia. J Immunol. 2009;183:7023-30 pubmed publisher
Chen Y, Hao Q, Kim H, Su H, Letarte M, Karumanchi S, et al. Soluble endoglin modulates aberrant cerebral vascular remodeling. Ann Neurol. 2009;66:19-27 pubmed publisher
Blankley R, Gaskell S, Whetton A, Dive C, Baker P, Myers J. A proof-of-principle gel-free proteomics strategy for the identification of predictive biomarkers for the onset of pre-eclampsia. BJOG. 2009;116:1473-80 pubmed publisher
Shariat S, Karam J, Walz J, Roehrborn C, Montorsi F, Margulis V, et al. Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers. Clin Cancer Res. 2008;14:3785-91 pubmed publisher
Svatek R, Karam J, Roehrborn C, Karakiewicz P, Slawin K, Shariat S. Preoperative plasma endoglin levels predict biochemical progression after radical prostatectomy. Clin Cancer Res. 2008;14:3362-6 pubmed publisher
Karam J, Svatek R, Karakiewicz P, Gallina A, Roehrborn C, Slawin K, et al. Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer. Clin Cancer Res. 2008;14:1418-22 pubmed publisher
Levine R, Lam C, Qian C, Yu K, Maynard S, Sachs B, et al. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med. 2006;355:992-1005 pubmed
Furstenberger G, von Moos R, Lucas R, Thurlimann B, Senn H, Hamacher J, et al. Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer. Br J Cancer. 2006;94:524-31 pubmed
product information
master code :
DNDG00
SKU :
DNDG00
product name :
Human Endoglin/CD105 Quantikine ELISA Kit
unit size :
1 Kit
description :
The Human Endoglin/CD105 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human Endoglin/CD105 in cell culture supernates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul).
target :
Endoglin/CD105
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human Endoglin
gene symbol :
ENG
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
elisaSensitivity :
0.03 ng/mL
elisaRange :
0.16 - 10 ng/mL
top caption :
Human Endoglin/CD105 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human Endoglin Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Endoglin in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human Endoglin and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Endoglin showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring Endoglin.
alt names :
CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, ENG, HHT1FLJ41744, ORW, ORW1
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.