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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Total MMP-7 Quantikine ELISA Kit
catalog :
DMP700
quantity :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
price :
655 USD
citations: 39
Reference
Jiang J, Dong R, Du M, Chen G, Yang J, Xie X, et al. Serum matrix metalloproteinase-7 for discriminating biliary atresia: a diagnostic accuracy and validation study. J Transl Med. 2024;22:636 pubmed publisher
Yin T, Chen S, Zhou R, Liu W, Diao M, Li L. Relationships of serum MMP-7 and clinical characteristics in choledochal cyst children. BMC Surg. 2024;24:195 pubmed publisher
Canela V, Bowen W, Ferreira R, Syed F, Lingeman J, Sabo A, et al. A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease. Nat Commun. 2023;14:4140 pubmed publisher
Kubik A, das Virgens I, Szab xf3 A, V xe1 radi M, Csizmarik A, Keszthelyi A, et al. Comprehensive Analysis of the Prognostic Value of Circulating MMP-7 Levels in Urothelial Carcinoma: A Combined Cohort Analysis, Systematic Review, and Meta-Analysis. Int J Mol Sci. 2023;24: pubmed publisher
Bahabayi A, Yang N, Xu T, Xue Y, Ma L, Gu X, et al. Expression of Matrix Metalloproteinase-2,-7,-9 in Serum during Pregnancy in Patients with Pre-Eclampsia: A Prospective Study. Int J Environ Res Public Health. 2022;19: pubmed publisher
Sz xe9 les x, Kov xe1 cs P, Csizmarik A, V xe1 radi M, Riesz P, Fazekas T, et al. High Pretreatment Serum PD-L1 Levels Are Associated with Muscle Invasion and Shorter Survival in Upper Tract Urothelial Carcinoma. Biomedicines. 2022;10: pubmed publisher
Ciszewski W, Chmielewska Kassassir M, Wozniak L, Sobierajska K. Thymidylate Synthase Overexpression Drives the Invasive Phenotype in Colon Cancer Cells. Biomedicines. 2022;10: pubmed publisher
Zhang J, Cao C, Wan L, Zhang W, Liu Z, Wang J, et al. Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway. World J Gastroenterol. 2022;28:1781-1797 pubmed publisher
Chávez Galán L, Ruiz A, Martinez Espinosa K, Aguilar Duran H, Torres M, Falfan Valencia R, et al. Circulating Levels of PD-L1, TIM-3 and MMP-7 Are Promising Biomarkers to Differentiate COVID-19 Patients That Require Invasive Mechanical Ventilation. Biomolecules. 2022;12: pubmed publisher
Kovács P, Mayer T, Csizmarik A, Varadi M, Olah C, Széles Á, et al. Elevated Pre-Treatment Serum MMP-7 Levels Are Associated with the Presence of Metastasis and Poor Survival in Upper Tract Urothelial Carcinoma. Biomedicines. 2022;10: pubmed publisher
Ancona S, Orpianesi E, Bernardelli C, Chiaramonte E, Chiaramonte R, Terraneo S, et al. Differential Modulation of Matrix Metalloproteinases-2 and -7 in LAM/TSC Cells. Biomedicines. 2021;9: pubmed publisher
Tellman T, Cruz L, Grindel B, Farach Carson M. Cleavage of the Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex by Matrix Metalloproteinase 7/Matrilysin Triggers Prostate Cancer Cell Dyscohesion and Migration. Int J Mol Sci. 2021;22: pubmed publisher
Fang F, Luo W, Yang M, Yang P, Yang X. Urinary Matrix Metalloproteinase-7 and Prediction of AKI Progression Post Cardiac Surgery. Dis Markers. 2019;2019:9217571 pubmed publisher
Buendía Roldán I, Machuca N, Mejia M, Maldonado M, Pardo A, Selman M. Lower levels of α-Klotho in serum are associated with decreased lung function in individuals with interstitial lung abnormalities. Sci Rep. 2019;9:10801 pubmed publisher
Justice J, Nambiar A, Tchkonia T, Lebrasseur N, Pascual R, Hashmi S, et al. Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study. EBioMedicine. 2019;40:554-563 pubmed publisher
Zhang J, Ren P, Wang Y, Feng S, Wang C, Shen X, et al. Serum Matrix Metalloproteinase-7 Level is Associated with Fibrosis and Renal Survival in Patients with IgA Nephropathy. Kidney Blood Press Res. 2017;42:541-552 pubmed publisher
Piedra F, Mei M, Avadhanula V, Mehta R, Aideyan L, Garofalo R, et al. The interdependencies of viral load, the innate immune response, and clinical outcome in children presenting to the emergency department with respiratory syncytial virus-associated bronchiolitis. PLoS ONE. 2017;12:e0172953 pubmed publisher
Lundmark A, Johannsen G, Eriksson K, Kats A, Jansson L, Tervahartiala T, et al. Mucin 4 and matrix metalloproteinase 7 as novel salivary biomarkers for periodontitis. J Clin Periodontol. 2017;44:247-254 pubmed publisher
Bchir S, Nasr H, Bouchet S, Benzarti M, Garrouch A, Tabka Z, et al. Concomitant elevations of MMP-9, NGAL, proMMP-9/NGAL and neutrophil elastase in serum of smokers with chronic obstructive pulmonary disease. J Cell Mol Med. 2017;21:1280-1291 pubmed publisher
Chen C, Chang A, Li S, Tsai H, Shiu L, Su L, et al. Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer. Mol Cancer. 2015;14:83 pubmed publisher
Chen I, Chiang W, Huang H, Chen P, Shen Y, Chiang H. Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis. Mol Cancer. 2014;13:254 pubmed publisher
Keeratichamroen S, Leelawat K, Thongtawee T, Narong S, Aegem U, Tujinda S, et al. Expression of CD24 in cholangiocarcinoma cells is associated with disease progression and reduced patient survival. Int J Oncol. 2011;39:873-81 pubmed publisher
Fukuda A, Wang S, Morris J, Folias A, Liou A, Kim G, et al. Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression. Cancer Cell. 2011;19:441-55 pubmed publisher
Szarvas T, Jager T, Becker M, Tschirdewahn S, Niedworok C, Kovalszky I, et al. Validation of circulating MMP-7 level as an independent prognostic marker of poor survival in urinary bladder cancer. Pathol Oncol Res. 2011;17:325-32 pubmed publisher
Szarvas T, Singer B, Becker M, vom Dorp F, Jager T, Szendroi A, et al. Urinary matrix metalloproteinase-7 level is associated with the presence of metastasis in bladder cancer. BJU Int. 2011;107:1069-73 pubmed publisher
Szarvas T, Becker M, vom Dorp F, Meschede J, Scherag A, Bankfalvi A, et al. Elevated serum matrix metalloproteinase 7 levels predict poor prognosis after radical prostatectomy. Int J Cancer. 2011;128:1486-92 pubmed publisher
Szarvas T, Becker M, vom Dorp F, Gethmann C, Totsch M, Bankfalvi A, et al. Matrix metalloproteinase-7 as a marker of metastasis and predictor of poor survival in bladder cancer. Cancer Sci. 2010;101:1300-8 pubmed publisher
Reikvam H, Hatfield K, Oyan A, Kalland K, Kittang A, Bruserud O. Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation. Eur J Haematol. 2010;84:239-51 pubmed publisher
Yeh Y, Sheu B, Cheng H, Wang Y, Yang H, Wu J. Elevated serum matrix metalloproteinase-3 and -7 in H. pylori-related gastric cancer can be biomarkers correlating with a poor survival. Dig Dis Sci. 2010;55:1649-57 pubmed publisher
Yue W, Sun Q, Landreneau R, Wu C, Siegfried J, Yu J, et al. Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression. Cancer Res. 2009;69:6339-46 pubmed publisher
Gogly B, Fournier B, Couty L, Naveau A, Brasselet C, Durand E, et al. Gingival fibroblast inhibits MMP-7: evaluation in an ex vivo aorta model. J Mol Cell Cardiol. 2009;47:296-303 pubmed publisher
Jung K, Ramankulov A, Schrader M, Miller K, Lein M. Circulating matrix metalloproteinase-7: an early or metastatic marker for renal cell carcinoma?. Clin Chem. 2008;54:1927-9 pubmed publisher
Rosas I, Richards T, Konishi K, Zhang Y, Gibson K, Lokshin A, et al. MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med. 2008;5:e93 pubmed publisher
Huh J, Kim D, Oh Y, Shim T, Lim C, Lee S, et al. Is metalloproteinase-7 specific for idiopathic pulmonary fibrosis?. Chest. 2008;133:1101-6 pubmed
Chaigneau C, Cabioch T, Beaumont K, Betsou F. Serum biobank certification and the establishment of quality controls for biological fluids: examples of serum biomarker stability after temperature variation. Clin Chem Lab Med. 2007;45:1390-5 pubmed
Hawinkels L, Verspaget H, Van den Berg M, Hanemaaijer R, Sier C. Determination of matrilysin activity in gastrointestinal neoplasia. Eur J Clin Invest. 2007;37:598-9 pubmed
McLennan S, Kelly D, Schache M, Waltham M, Dy V, Langham R, et al. Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?. Kidney Int. 2007;72:481-8 pubmed
Meinhold Heerlein I, Bauerschlag D, Zhou Y, Sapinoso L, Ching K, Frierson H, et al. An integrated clinical-genomics approach identifies a candidate multi-analyte blood test for serous ovarian carcinoma. Clin Cancer Res. 2007;13:458-66 pubmed
Ma D, Yao J, Kuo M, See L, Lin K, Chen S, et al. Generation of endostatin by matrix metalloproteinase and cathepsin from human limbocorneal epithelial cells cultivated on amniotic membrane. Invest Ophthalmol Vis Sci. 2007;48:644-51 pubmed
product information
master code :
DMP700
SKU :
DMP700
product name :
Human Total MMP-7 Quantikine ELISA Kit
unit size :
1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))
description :
The Human Total MMP-7 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human MMP-7 in cell culture supernates (25 ul), serum (25 ul), heparin plasma (25 ul), saliva (25 ul), urine (50 ul).
target :
MMP-7
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human MMP-7
gene symbol :
MMP7
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (25 uL), Serum (25 uL), Heparin Plasma (25 uL), Saliva (25 uL), Urine (50 uL)
elisaSensitivity :
0.094 ng/mL
elisaRange :
0.16 - 10 ng/mL
top caption :
Human Total MMP-7 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Human MMP-7 Immunoassay is a 4.5 hour solid phase ELISA designed to measure MMP-7 in cell culture supernates, serum, plasma, saliva, and urine. It contains NS0-expressed recombinant human MMP-7 and antibodies raised against the recombinant factor. The Quantikine kit detected both pro- and active forms of recombinant human MMP-7. Natural human MMP-7 showed dose-response curves that were parallel to the standard curves obtained using the kit standards, indicating that this kit can be used to determine relative levels of natural human MMP-7.
alt names :
EC 3.4.24, EC 3.4.24.23, matrilysin, Matrin, matrix metallopeptidase 7 (matrilysin, uterine), matrix metalloproteinase 7 (matrilysin, uterine), Matrix metalloproteinase-7, MMP7, MMP-7, MPSL1, PUMP1, PUMP-1, Pump-1 protease, uterine matrilysin, Uterine metalloproteinase
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.