Human CCL4/MIP-1 beta Quantikine ELISA Kit | R&D Systems DMB00 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human CCL4/MIP-1 beta Quantikine ELISA Kit

catalog :

DMB00

quantity :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

price :

655 USD

citations: 48

Reference
Scovino A, Dahab E, Diniz Lima I, de Senna Silveira E, Barroso S, Cardoso K, et al. A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants. Microorganisms. 2024;12: pubmed publisher
Sengupta S, Board N, Wu F, Moskovljevic M, Douglass J, Zhang J, et al. TCR-mimic bispecific antibodies to target the HIV-1 reservoir. Proc Natl Acad Sci U S A. 2022;119:e2123406119 pubmed publisher
Liu Z, Liu J, Zhang T, Li L, Zhang S, Jia H, et al. Distinct BTK inhibitors differentially induce apoptosis but similarly suppress chemotaxis and lipid accumulation in mantle cell lymphoma. BMC Cancer. 2021;21:732 pubmed publisher
Pandolfi E, Panera N, Alisi A, Carloni E, Russo L, Campagna I, et al. Cytokine expression patterns in hospitalized children with Bordetella pertussis, Rhinovirus or co-infection. Sci Rep. 2021;11:10948 pubmed publisher
Avila L, Neves M, Abreu A, Fiuza C, Fukusawa L, Meziat Filho N, et al. Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial. J Bodyw Mov Ther. 2021;26:428-434 pubmed publisher
Sivina M, Xiao L, Kim E, Vaca A, Chen S, Keating M, et al. CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia. Leukemia. 2021;35:1610-1620 pubmed publisher
Hackel A, Aksamit A, Bruderek K, Lang S, Brandau S. TNF-α and IL-1β sensitize human MSC for IFN-γ signaling and enhance neutrophil recruitment. Eur J Immunol. 2021;51:319-330 pubmed publisher
Sadeghi L, Arvidsson G, Merrien M, M Wasik A, Görgens A, Smith C, et al. Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells. Cancers (Basel). 2020;12: pubmed publisher
Lu Y, Yoo B, Ng A, Kim J, Yeom S, TANG J, et al. 4D electron microscopy of T cell activation. Proc Natl Acad Sci U S A. 2019;116:22014-22019 pubmed publisher
Aziz N, Detels R, Quint J, Gjertson D, Ryner T, Butch A. Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests. BMC Immunol. 2019;20:33 pubmed publisher
Bournazou E, Samuels J, Zhou H, Krasnokutsky S, Patel J, Han T, et al. Vascular Adhesion Protein-1 (VAP-1) as Predictor of Radiographic Severity in Symptomatic Knee Osteoarthritis in the New York University Cohort. Int J Mol Sci. 2019;20: pubmed publisher
Zhang N, Zhang G, Liu N, Lin W, Ji S, Zheng M, et al. A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models. Oncotarget. 2017;8:111495-111507 pubmed publisher
Johdi N, Mazlan L, Sagap I, Jamal R. Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps. Cytokine. 2017;99:35-42 pubmed publisher
ten Hacken E, Sivina M, Kim E, O Brien S, Wierda W, Ferrajoli A, et al. Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia. J Immunol. 2016;197:2522-31 pubmed publisher
Aziz N, Detels R, Quint J, Li Q, Gjertson D, Butch A. Stability of cytokines, chemokines and soluble activation markers in unprocessed blood stored under different conditions. Cytokine. 2016;84:17-24 pubmed publisher
Sadeghi M, Lahdou I, Oweira H, Daniel V, Terness P, Schmidt J, et al. Serum levels of chemokines CCL4 and CCL5 in cirrhotic patients indicate the presence of hepatocellular carcinoma. Br J Cancer. 2015;113:756-62 pubmed publisher
Balakrishnan K, Peluso M, Fu M, Rosin N, Burger J, Wierda W, et al. The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL. Leukemia. 2015;29:1811-22 pubmed publisher
Pundir P, Catalli A, Leggiadro C, Douglas S, Kulka M. Pleurocidin, a novel antimicrobial peptide, induces human mast cell activation through the FPRL1 receptor. Mucosal Immunol. 2014;7:177-87 pubmed publisher
de Oliveira Pinto L, Marinho C, Povoa T, de Azeredo E, de Souza L, Barbosa L, et al. Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever. PLoS ONE. 2012;7:e38527 pubmed publisher
Ponader S, Chen S, Buggy J, Balakrishnan K, Gandhi V, Wierda W, et al. The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood. 2012;119:1182-9 pubmed publisher
Johnson T, McLellan J, Graham B. Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2. J Virol. 2012;86:1339-47 pubmed publisher
Badoux X, Keating M, Wen S, Lee B, Sivina M, Reuben J, et al. Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia. Blood. 2011;118:3489-98 pubmed publisher
Sivina M, Hartmann E, Kipps T, Rassenti L, Krupnik D, Lerner S, et al. CCL3 (MIP-1?) plasma levels and the risk for disease progression in chronic lymphocytic leukemia. Blood. 2011;117:1662-9 pubmed publisher
Tatara Y, Ohishi M, Yamamoto K, Shiota A, Hayashi N, Iwamoto Y, et al. Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species. J Mol Cell Cardiol. 2009;47:104-11 pubmed publisher
Hartl D, Krauss Etschmann S, Koller B, Hordijk P, Kuijpers T, Hoffmann F, et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol. 2008;181:8053-67 pubmed
Ferrarini M, Delfanti F, Gianolini M, Rizzi C, Alfano M, Lazzarin A, et al. NF-kappa B modulates sensitivity to apoptosis, proinflammatory and migratory potential in short- versus long-term cultured human gamma delta lymphocytes. J Immunol. 2008;181:5857-64 pubmed
Olsnes A, Ryningen A, Ersvaer E, Bruserud Ø. In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22. J Interferon Cytokine Res. 2008;28:297-310 pubmed publisher
Mayr F, Spiel A, Leitner J, Firbas C, Kliegel T, Jilma Stohlawetz P, et al. Duffy antigen modifies the chemokine response in human endotoxemia. Crit Care Med. 2008;36:159-65 pubmed
Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, et al. Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions. Int J Cancer. 2008;122:769-76 pubmed
Bolovan Fritts C, Spector S. Endothelial damage from cytomegalovirus-specific host immune response can be prevented by targeted disruption of fractalkine-CX3CR1 interaction. Blood. 2008;111:175-82 pubmed
Bolovan Fritts C, Trout R, Spector S. High T-cell response to human cytomegalovirus induces chemokine-mediated endothelial cell damage. Blood. 2007;110:1857-63 pubmed
Benson M, Langston M, Adner M, Andersson B, Torinssson Naluai A, Cardell L. A network-based analysis of the late-phase reaction of the skin. J Allergy Clin Immunol. 2006;118:220-5 pubmed
Tikhonov I, Deetz C, Paca R, Berg S, Lukyanenko V, Lim J, et al. Human Vgamma2Vdelta2 T cells contain cytoplasmic RANTES. Int Immunol. 2006;18:1243-51 pubmed
Kristjansson S, Bjarnarson S, Wennergren G, Palsdottir A, Arnadottir T, Haraldsson A, et al. Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like response. J Allergy Clin Immunol. 2005;116:805-11 pubmed
Capelli A, Di Stefano A, Gnemmi I, Donner C. CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis. Eur Respir J. 2005;25:701-7 pubmed
Grygorczuk S, Pancewicz S, Zajkowska J, Kondrusik M, Rwierzbińska R, Hermanowska Szpakowicz T. Concentrations of macrophage inflammatory proteins MIP-1alpha and MIP-1beta and interleukin 8 (il-8) in lyme borreliosis. Infection. 2004;32:350-5 pubmed
Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, et al. Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. J Gen Virol. 2004;85:2603-13 pubmed
Megjugorac N, Young H, Amrute S, Olshalsky S, Fitzgerald Bocarsly P. Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells. J Leukoc Biol. 2004;75:504-14 pubmed
Burton C, Hardy G, Sullivan A, Nelson M, Gazzard B, Gotch F, et al. Impact of NNRTI compared to PI-based highly active antiretroviral therapy on CCR5 receptor expression, beta-chemokines and IL-16 secretion in HIV-1 infection. Clin Exp Immunol. 2002;130:286-92 pubmed
Messmer D, Jacque J, Santisteban C, Bristow C, Han S, Villamide Herrera L, et al. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells. J Immunol. 2002;169:4172-82 pubmed
Dagna L, Iellem A, Biswas P, Resta D, Tantardini F, Fortis C, et al. Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes. Eur J Immunol. 2002;32:2934-43 pubmed
Honczarenko M, Le Y, Glodek A, Majka M, Campbell J, Ratajczak M, et al. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Blood. 2002;100:2321-9 pubmed
Ciesielski C, Andreakos E, Foxwell B, Feldmann M. TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion. Eur J Immunol. 2002;32:2037-45 pubmed
Milliken D, Scotton C, Raju S, Balkwill F, Wilson J. Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites. Clin Cancer Res. 2002;8:1108-14 pubmed
Binninger Schinzel D, Norley S, Adler H, Oberg H, Kurth R. Simian immunodeficiency viruses with defective nef genes show increased susceptibility to the noncytotoxic antiviral activity of CD8+ lymphocytes. Virology. 2002;294:209-21 pubmed
Lehner T, Wang Y, Cranage M, Tao L, Mitchell E, Bravery C, et al. Up-regulation of beta-chemokines and down-modulation of CCR5 co-receptors inhibit simian immunodeficiency virus transmission in non-human primates. Immunology. 2000;99:569-77 pubmed
Yates S, Burgess L, Kocsis Angle J, Antal J, Dority M, Embury P, et al. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. J Neurochem. 2000;74:1017-25 pubmed
Gauduin M, Glickman R, Ahmad S, Yilma T, Johnson R. Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and beta-chemokine production. Proc Natl Acad Sci U S A. 1999;96:14031-6 pubmed

product information

master code :

DMB00

SKU :

DMB00

product name :

Human CCL4/MIP-1 beta Quantikine ELISA Kit

unit size :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

description :

The Human CCL4/MIP-1 beta Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human CCL4/MIP-1 beta in cell culture supernates (10 ul), serum (150 ul), edta plasma (150 ul), heparin plasma (150 ul), citrate plasma (150 ul).

target :

CCL4/MIP-1 beta

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human MIP-1 beta

gene symbol :

CCL4

kit type :

Solid Phase Sandwich ELISA

assay length :

3.0 hours or 4.5 hours

elisaSampleTypes :

Cell Culture Supernates (10 uL), Serum (150 uL), EDTA Plasma (150 uL), Heparin Plasma (150 uL), Citrate Plasma (150 uL)

elisaSensitivity :

4 pg/mL (Cell Culture Supernates), 11 pg/mL (Serum, Heparin Plasma, Citrate Plasma, EDTA Plasma)

elisaRange :

15.60 - 1000 pg/mL (Cell Culture Supernates), 31.20 - 2000 pg/mL (Serum, Heparin Plasma, Citrate Plasma, EDTA Plasma)

top caption :

Human CCL4/MIP-1 beta ELISA Cell Culture Supernate Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human MIP-1 beta Immunoassay is a 3.0 or 4.5 hour solid phase ELISA designed to measure MIP-1 beta in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant human MIP-1 beta (Act-2 variant) and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant human MIP-1 beta. Results obtained using natural human MIP-1 beta showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human MIP-1 beta.

alt names :

ACT2, ACT-2, AT744.1, C-C motif chemokine 4, chemokine (C-C motif) ligand 4, Exodus-3, G-26, G-26 T-lymphocyte-secreted protein, HC21, LAG1, LAG-1, Lymphocyte activation gene 1 protein, Macrophage inflammatory protein 1-beta, MIP1 beta, MIP-1 beta, MIP1B, MIP1B1, MIP-1-beta, MIP-1-beta(1-69), PAT 744, Protein H400, SCYA2, SCYA4, secreted protein G-26, SIS-gamma, small inducible cytokine A4 (homologous to mouse Mip-1b), Small-inducible cytokine A4, T-cell activation protein 2

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.