Human CCL3/MIP-1 alpha Quantikine ELISA Kit | R&D Systems DMA00 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human CCL3/MIP-1 alpha Quantikine ELISA Kit

catalog :

DMA00

quantity :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

price :

655 USD

citations: 62

Reference
Kido R, Hiroshima Y, Kido J, Bando M, Yoshida K, Inagaki Y, et al. Lipocalin 2 inhibits the expressions of interleukin-8 and macrophage inflammatory protein-1α in human neutrophil-like cells. J Oral Biosci. 2025;67:100624 pubmed publisher
Polis B, Zeman K, Zakrzewski K, Fabijan A, Nowos x142 awska E. Peripheral white blood cell patterns in children with hydrocephalus as a response to ventriculo-peritoneal shunt infection. PLoS ONE. 2024;19:e0308131 pubmed publisher
Scovino A, Dahab E, Diniz Lima I, de Senna Silveira E, Barroso S, Cardoso K, et al. A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants. Microorganisms. 2024;12: pubmed publisher
Tsai T, Alwees M, Asaad M, Theile J, Kakkassery V, Dick H, et al. Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy. PLoS ONE. 2023;18:e0280488 pubmed publisher
Terpos E, Ntanasis Stathopoulos I, Kastritis E, Hatjiharissi E, Katodritou E, Eleutherakis Papaiakovou E, et al. Daratumumab Improves Bone Turnover in Relapsed/Refractory Multiple Myeloma; Phase 2 Study "REBUILD". Cancers (Basel). 2022;14: pubmed publisher
Liu Z, Liu J, Zhang T, Li L, Zhang S, Jia H, et al. Distinct BTK inhibitors differentially induce apoptosis but similarly suppress chemotaxis and lipid accumulation in mantle cell lymphoma. BMC Cancer. 2021;21:732 pubmed publisher
Mannakandath M, Kamran M, Udeabor S, Hameed M, Ajmal M, Alshahrani I. Effect of ultrasonic scaling with adjunctive photodynamic therapy on the treatment of gingival inflammation among diabetic patients undergoing fixed orthodontic treatment. Photodiagnosis Photodyn Ther. 2021;35:102360 pubmed publisher
Pandolfi E, Panera N, Alisi A, Carloni E, Russo L, Campagna I, et al. Cytokine expression patterns in hospitalized children with Bordetella pertussis, Rhinovirus or co-infection. Sci Rep. 2021;11:10948 pubmed publisher
Avila L, Neves M, Abreu A, Fiuza C, Fukusawa L, Meziat Filho N, et al. Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial. J Bodyw Mov Ther. 2021;26:428-434 pubmed publisher
Terpos E, Ntanasis Stathopoulos I, Katodritou E, Kyrtsonis M, Douka V, Spanoudakis E, et al. Carfilzomib Improves Bone Metabolism in Patients with Advanced Relapsed/Refractory Multiple Myeloma: Results of the CarMMa Study. Cancers (Basel). 2021;13: pubmed publisher
Sendic S, Mansouri L, Lundberg S, Nopp A, Jacobson S, Lundahl J. B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy. PLoS ONE. 2021;16:e0248056 pubmed publisher
Sivina M, Xiao L, Kim E, Vaca A, Chen S, Keating M, et al. CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia. Leukemia. 2021;35:1610-1620 pubmed publisher
Peeters T, Martens S, D Onofrio V, Stappers M, van der Hilst J, Houben B, et al. An observational study of innate immune responses in patients with acute appendicitis. Sci Rep. 2020;10:17352 pubmed publisher
Gerosa Neto J, Monteiro P, Inoue D, Antunes B, Batatinha H, Dorneles G, et al. High- and moderate-intensity training modify LPS-induced ex-vivo interleukin-10 production in obese men in response to an acute exercise bout. Cytokine. 2020;136:155249 pubmed publisher
Kodama T, Koma Y, Arai N, Kido A, Urakawa N, Nishio M, et al. CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways. Lab Invest. 2020;100:1140-1157 pubmed publisher
Sadeghi L, Arvidsson G, Merrien M, M Wasik A, Görgens A, Smith C, et al. Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells. Cancers (Basel). 2020;12: pubmed publisher
Dampmann M, Görgens A, Möllmann M, Murke F, Duhrsen U, Giebel B, et al. CpG stimulation of chronic lymphocytic leukemia cells induces a polarized cell shape and promotes migration in vitro and in vivo. PLoS ONE. 2020;15:e0228674 pubmed publisher
Aziz N, Detels R, Quint J, Gjertson D, Ryner T, Butch A. Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests. BMC Immunol. 2019;20:33 pubmed publisher
Wang W, Chu H, Zhong Z, Qi X, Cheng R, Qin R, et al. Platelet-secreted CCL3 and its receptor CCR5 promote invasive and migratory abilities of anaplastic thyroid carcinoma cells via MMP-1. Cell Signal. 2019;63:109363 pubmed publisher
Wang J, Wu G, Manick B, Hernandez V, Renelt M, Erickson C, et al. VSIG-3 as a ligand of VISTA inhibits human T-cell function. Immunology. 2019;156:74-85 pubmed publisher
Zhang Y, Li B, Zhou Z. A cross-sectional study: serum CCL3/MIP-1α levels may reflect lumbar intervertebral disk degeneration in Han Chinese people. J Pain Res. 2018;11:497-503 pubmed publisher
Stiff A, Trikha P, Mundy Bosse B, McMichael E, Mace T, Benner B, et al. Nitric Oxide Production by Myeloid-Derived Suppressor Cells Plays a Role in Impairing Fc Receptor-Mediated Natural Killer Cell Function. Clin Cancer Res. 2018;24:1891-1904 pubmed publisher
Zhang N, Zhang G, Liu N, Lin W, Ji S, Zheng M, et al. A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models. Oncotarget. 2017;8:111495-111507 pubmed publisher
ten Hacken E, Sivina M, Kim E, O Brien S, Wierda W, Ferrajoli A, et al. Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia. J Immunol. 2016;197:2522-31 pubmed publisher
Balakrishnan K, Peluso M, Fu M, Rosin N, Burger J, Wierda W, et al. The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL. Leukemia. 2015;29:1811-22 pubmed publisher
Hashimoto A, Tanaka T, Itoh Y, Yamagata A, Kitamura N, Tazawa R, et al. Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitro. Cytokine. 2014;68:118-26 pubmed publisher
Ponader S, Chen S, Buggy J, Balakrishnan K, Gandhi V, Wierda W, et al. The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood. 2012;119:1182-9 pubmed publisher
Johnson T, McLellan J, Graham B. Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2. J Virol. 2012;86:1339-47 pubmed publisher
Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Leçon V, et al. Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury. Crit Care Med. 2012;40:21-8 pubmed publisher
Sivina M, Hartmann E, Kipps T, Rassenti L, Krupnik D, Lerner S, et al. CCL3 (MIP-1?) plasma levels and the risk for disease progression in chronic lymphocytic leukemia. Blood. 2011;117:1662-9 pubmed publisher
Su Y, Amiri K, Horton L, Yu Y, Ayers G, Koehler E, et al. A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets. Clin Cancer Res. 2010;16:348-57 pubmed publisher
Calmy A, Gayet Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, et al. HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial. AIDS. 2009;23:929-39 pubmed
Mabilleau G, Sabokbar A. Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE. 2009;4:e4173 pubmed publisher
Olsnes A, Ryningen A, Ersvaer E, Bruserud Ø. In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22. J Interferon Cytokine Res. 2008;28:297-310 pubmed publisher
Pene J, Chevalier S, Preisser L, Venereau E, Guilleux M, Ghannam S, et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J Immunol. 2008;180:7423-30 pubmed
Le Quement C, Guenon I, Gillon J, Lagente V, Boichot E. MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2008;294:L1076-84 pubmed publisher
Pokkali S, Das S, R L. Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. Cytokine. 2008;41:307-14 pubmed publisher
Mayr F, Spiel A, Leitner J, Firbas C, Kliegel T, Jilma Stohlawetz P, et al. Duffy antigen modifies the chemokine response in human endotoxemia. Crit Care Med. 2008;36:159-65 pubmed
Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, et al. Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions. Int J Cancer. 2008;122:769-76 pubmed
Abonyo B, Lebby K, Tonry J, Ahmad M, Heiman A. Modulation of eotaxin-3 (CCL26) in alveolar type II epithelial cells. Cytokine. 2006;36:237-44 pubmed
Martinez de la Torre Y, Buracchi C, Borroni E, Dupor J, Bonecchi R, Nebuloni M, et al. Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Proc Natl Acad Sci U S A. 2007;104:2319-24 pubmed
Kang M, Homer R, Gallo A, Lee C, Crothers K, Cho S, et al. IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. J Immunol. 2007;178:1948-59 pubmed
Tikhonov I, Deetz C, Paca R, Berg S, Lukyanenko V, Lim J, et al. Human Vgamma2Vdelta2 T cells contain cytoplasmic RANTES. Int Immunol. 2006;18:1243-51 pubmed
Wong C, Cheung P, Ip W, Lam C. Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB. Am J Respir Cell Mol Biol. 2005;33:186-94 pubmed
Capelli A, Di Stefano A, Gnemmi I, Donner C. CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis. Eur Respir J. 2005;25:701-7 pubmed
Grygorczuk S, Pancewicz S, Zajkowska J, Kondrusik M, Rwierzbińska R, Hermanowska Szpakowicz T. Concentrations of macrophage inflammatory proteins MIP-1alpha and MIP-1beta and interleukin 8 (il-8) in lyme borreliosis. Infection. 2004;32:350-5 pubmed
Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, et al. Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. J Gen Virol. 2004;85:2603-13 pubmed
Parameswaran K, Liang H, Fanat A, Watson R, Snider D, O Byrne P. Role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in asthma. J Allergy Clin Immunol. 2004;114:73-9 pubmed
Choi E, Jakubzick C, Carpenter K, Kunkel S, Evanoff H, Martinez F, et al. Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia. Am J Respir Crit Care Med. 2004;170:508-15 pubmed
Wang C, Liu M, Huang Y, Chen H. Up-regulation of XCR1 expression in rheumatoid joints. Rheumatology (Oxford). 2004;43:569-73 pubmed
Wang C, Liu M. Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritis. Clin Exp Immunol. 2003;132:371-8 pubmed
Messmer D, Jacque J, Santisteban C, Bristow C, Han S, Villamide Herrera L, et al. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells. J Immunol. 2002;169:4172-82 pubmed
Honczarenko M, Le Y, Glodek A, Majka M, Campbell J, Ratajczak M, et al. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Blood. 2002;100:2321-9 pubmed
Ciesielski C, Andreakos E, Foxwell B, Feldmann M. TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion. Eur J Immunol. 2002;32:2037-45 pubmed
Milliken D, Scotton C, Raju S, Balkwill F, Wilson J. Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites. Clin Cancer Res. 2002;8:1108-14 pubmed
Binninger Schinzel D, Norley S, Adler H, Oberg H, Kurth R. Simian immunodeficiency viruses with defective nef genes show increased susceptibility to the noncytotoxic antiviral activity of CD8+ lymphocytes. Virology. 2002;294:209-21 pubmed
Hurst S, Wilkinson T, McLoughlin R, Jones S, Horiuchi S, Yamamoto N, et al. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity. 2001;14:705-14 pubmed
Loeuillet C, Bernard G, Remy Martin J, Saas P, Herve P, Douay L, et al. Distinct hematopoietic support by two human stromal cell lines. Exp Hematol. 2001;29:736-45 pubmed
Böttcher M, Jenmalm M, Bjorksten B, Garofalo R. Chemoattractant factors in breast milk from allergic and nonallergic mothers. Pediatr Res. 2000;47:592-7 pubmed
Lehner T, Wang Y, Cranage M, Tao L, Mitchell E, Bravery C, et al. Up-regulation of beta-chemokines and down-modulation of CCR5 co-receptors inhibit simian immunodeficiency virus transmission in non-human primates. Immunology. 2000;99:569-77 pubmed
Yates S, Burgess L, Kocsis Angle J, Antal J, Dority M, Embury P, et al. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. J Neurochem. 2000;74:1017-25 pubmed
Gauduin M, Glickman R, Ahmad S, Yilma T, Johnson R. Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and beta-chemokine production. Proc Natl Acad Sci U S A. 1999;96:14031-6 pubmed

product information

master code :

DMA00

SKU :

DMA00

product name :

Human CCL3/MIP-1 alpha Quantikine ELISA Kit

unit size :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

description :

The Human CCL3/MIP-1 alpha Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human CCL3/MIP-1 alpha in cell culture supernates (10 ul), serum (200 ul), edta plasma (200 ul), heparin plasma (200 ul), citrate plasma (200 ul).

target :

CCL3/MIP-1 alpha

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human MIP-1 alpha

gene symbol :

CCL3

kit type :

Solid Phase Sandwich ELISA

assay length :

3.5 hours or 4.5 hours

elisaSampleTypes :

Cell Culture Supernates (10 uL), Serum (200 uL), EDTA Plasma (200 uL), Heparin Plasma (200 uL), Citrate Plasma (200 uL)

elisaSensitivity :

10 pg/mL

elisaRange :

31.20 - 1000 pg/mL (Cell Culture Supernates), 46.90 - 1500 pg/mL (Serum, Heparin Plasma, Citrate Plasma, EDTA Plasma)

top caption :

Human CCL3/MIP-1 alpha ELISA Cell Culture Supernate Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human MIP-1 alpha Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure MIP-1 alpha levels in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant human MIP-1 alpha and antibodies raised against the recombinant protein. Results obtained for naturally occurring human MIP-1 alpha showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural human MIP-1 alpha.

alt names :

C-C motif chemokine 3, MIP1-(a), AI323804, chemokine (C-C motif) ligand 3, G0S19-1, LD78a, LD78alpha, MIP1 alpha, MIP-1 alpha, Mip1a, MIP-1alpha, MIP1-alpha, PAT 464.1, SCYA3, SIS-beta

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.