Human Pro-MMP-13 Quantikine ELISA Kit | R&D Systems DM1300 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human Pro-MMP-13 Quantikine ELISA Kit

catalog :

DM1300

quantity :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

price :

655 USD

citations: 34

Reference
Sengprasert P, Waitayangkoon P, Kamenkit O, Sawatpanich A, Chaichana T, Wongphoom J, et al. Catabolic mediators from TLR2-mediated proteoglycan aggrecan peptide-stimulated chondrocytes are reduced by Lactobacillus-conditioned media. Sci Rep. 2024;14:18043 pubmed publisher
Shin J, Park S, Cho H, Kim J, Choi H. Adipokine human Resistin promotes obesity-associated inflammatory intervertebral disc degeneration via pro-inflammatory cytokine cascade activation. Sci Rep. 2022;12:8936 pubmed publisher
Jarecki J, Ma x142 ecka Masalska T, Kosior Jarecka E, Widuchowski W, Krasowski P, Gutbier M, et al. Concentration of Selected Metalloproteinases and Osteocalcin in the Serum and Synovial Fluid of Obese Women with Advanced Knee Osteoarthritis. Int J Environ Res Public Health. 2022;19: pubmed publisher
Hopkins T, Wright K, Kuiper N, Roberts S, Jermin P, Gallacher P, et al. An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans. Cells. 2021;10: pubmed publisher
Kuo C, Chen J, Lin L, Schmid Schonbein G, Chien S, Huang P, et al. Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance. Sci Rep. 2020;10:1725 pubmed publisher
Wehrle A, Witkos T, Unger S, Schneider J, Follit J, Hermann J, et al. Hypomorphic mutations of TRIP11 cause odontochondrodysplasia. JCI Insight. 2019;4: pubmed publisher
Thomas N, Wu W, Fleming B, Wei F, Chen Q, Wei L. Synovial inflammation plays a greater role in post-traumatic osteoarthritis compared to idiopathic osteoarthritis in the Hartley guinea pig knee. BMC Musculoskelet Disord. 2017;18:556 pubmed publisher
Yuan Y, Tan H, Dai P. Krüppel-Like Factor 2 Regulates Degradation of Type II Collagen by Suppressing the Expression of Matrix Metalloproteinase (MMP)-13. Cell Physiol Biochem. 2017;42:2159-2168 pubmed publisher
Liu Z, Li C, Meng X, Bai Y, Qi J, Wang J, et al. Hypoxia-inducible factor-l? mediates aggrecan and collagen ? expression via NOTCH1 signaling in nucleus pulposus cells during intervertebral disc degeneration. Biochem Biophys Res Commun. 2017;488:554-561 pubmed publisher
Zhang Q, Luo Q, Yuan X, Chai L, Li D, Liu J, et al. Atmospheric particulate matter2.5 promotes the migration and invasion of hepatocellular carcinoma cells. Oncol Lett. 2017;13:3445-3450 pubmed publisher
Weinmann D, Schlangen K, Andre S, Schmidt S, Walzer S, Kubista B, et al. Galectin-3 Induces a Pro-degradative/inflammatory Gene Signature in Human Chondrocytes, Teaming Up with Galectin-1 in Osteoarthritis Pathogenesis. Sci Rep. 2016;6:39112 pubmed publisher
Kostopoulou F, Gkretsi V, Malizos K, Iliopoulos D, Oikonomou P, Poultsides L, et al. Central role of SREBP-2 in the pathogenesis of osteoarthritis. PLoS ONE. 2012;7:e35753 pubmed publisher
Wang J, Shih K, Liou J, Wu Y, Chang A, Wang K, et al. Anti-arthritic effects of magnolol in human interleukin 1?-stimulated fibroblast-like synoviocytes and in a rat arthritis model. PLoS ONE. 2012;7:e31368 pubmed publisher
Yamakawa N, Uchida T, Matthay M, Makita K. Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2011;300:L516-25 pubmed publisher
Hashizume M, Mihara M. High molecular weight hyaluronic acid inhibits IL-6-induced MMP production from human chondrocytes by up-regulating the ERK inhibitor, MKP-1. Biochem Biophys Res Commun. 2010;403:184-9 pubmed publisher
Reikvam H, Hatfield K, Oyan A, Kalland K, Kittang A, Bruserud O. Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation. Eur J Haematol. 2010;84:239-51 pubmed publisher
Wunrau C, Schnaeker E, Freyth K, Pundt N, Wendholt D, Neugebauer K, et al. Establishment of a matrix-associated transepithelial resistance invasion assay to precisely measure the invasive potential of synovial fibroblasts. Arthritis Rheum. 2009;60:2606-11 pubmed publisher
Yammani R, Long D, Loeser R. Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes. Arthritis Rheum. 2009;60:792-800 pubmed publisher
Zayed N, Afif H, Chabane N, Mfuna Endam L, Benderdour M, Martel Pelletier J, et al. Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2. Arthritis Rheum. 2008;58:3530-40 pubmed publisher
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Agarwal A, Covic L, Sevigny L, Kaneider N, Lazarides K, Azabdaftari G, et al. Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer. Mol Cancer Ther. 2008;7:2746-57 pubmed publisher
Boanini E, Torricelli P, Gazzano M, Giardino R, Bigi A. Alendronate-hydroxyapatite nanocomposites and their interaction with osteoclasts and osteoblast-like cells. Biomaterials. 2008;29:790-6 pubmed
Vishnubhotla R, Sun S, Huq J, Bulic M, Ramesh A, Guzman G, et al. ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging. Lab Invest. 2007;87:1149-58 pubmed
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product information

master code :

DM1300

SKU :

DM1300

product name :

Human Pro-MMP-13 Quantikine ELISA Kit

unit size :

1 Kit (also 1 Pack (50 Plates), 1 Pack (6 Plates))

description :

The Human Pro-MMP-13 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human MMP-13 in cell culture supernates (50 ul).

target :

MMP-13

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human pro-MMP-13

gene symbol :

MMP13

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL)

elisaSensitivity :

21.3 pg/mL

elisaRange :

78.00 - 5000 pg/mL

top caption :

Human Pro-MMP-13 ELISA Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human Pro-MMP-13 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure pro-MMP-13 in cell culture supernates. It contains NS0-expressed recombinant human pro-MMP-13 and antibodies raised against the recombinant factor. The Quantikine kit will not detect recombinant human active MMP-13 existing in either free or TIMP-bound form. Natural human pro-MMP-13 showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards, indicating that this kit can be used to determine relative levels of natural human pro-MMP-13.

alt names :

CLG 3, CLG3EC 3.4.24, collagenase 3, EC 3.4.24.-, EC 3.4.24.22, EC 3.4.24.24, EC 3.4.24.35, EC 3.4.24.65, EC 3.4.24.7, MANDP1, matrix metallopeptidase 13 (collagenase 3), matrix metalloproteinase 13 (collagenase 3), Matrix metalloproteinase-13, MMP13, MMP-13

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.