Human LIGHT/TNFSF14 Quantikine ELISA Kit | R&D Systems DLIT00 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Human LIGHT/TNFSF14 Quantikine ELISA Kit

catalog :

DLIT00

quantity :

1 Kit

price :

655 USD

citations: 14

Reference
Grannes H, Ueland T, Simeone P, Liani R, Guagnano M, Aukrust P, et al. Liraglutide and not lifestyle intervention reduces soluble CD163 after comparable weight loss in obese participants with prediabetes or type 2 diabetes mellitus. Cardiovasc Diabetol. 2024;23:146 pubmed publisher
Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, et al. TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation. J Transl Med. 2023;21:544 pubmed publisher
da Silva Antunes R, Soldevila F, Pomaznoy M, Babor M, Bennett J, Tian Y, et al. A system-view of Bordetella pertussis booster vaccine responses in adults primed with whole-cell versus acellular vaccine in infancy. JCI Insight. 2021;6: pubmed publisher
Tavoosidana G, Ronquist G, Darmanis S, Yan J, Carlsson L, Wu D, et al. Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer. Proc Natl Acad Sci U S A. 2011;108:8809-14 pubmed publisher
Liu Y, Tuve S, Persson J, Beyer I, Yumul R, Li Z, et al. Adenovirus-mediated intratumoral expression of immunostimulatory proteins in combination with systemic Treg inactivation induces tumor-destructive immune responses in mouse models. Cancer Gene Ther. 2011;18:407-18 pubmed publisher
Landrø L, Ueland T, Otterdal K, Frøland S, Aukrust P. Persistently raised plasma levels of platelet-derived inflammatory mediators in HIV-infected patients during highly active anti-retroviral therapy. J Thromb Haemost. 2011;9:1075-7 pubmed publisher
Bassols J, Moreno Navarrete J, Ortega F, Ricart W, Fernandez Real J. LIGHT is associated with hypertriglyceridemia in obese subjects and increased cytokine secretion from cultured human adipocytes. Int J Obes (Lond). 2010;34:146-56 pubmed publisher
Mabilleau G, Sabokbar A. Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE. 2009;4:e4173 pubmed publisher
Sandberg W, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad F, et al. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis. Circ Res. 2009;104:60-8 pubmed publisher
Liu G, Fang L, Hjelmstrom P, Gao X. Enhanced plasma levels of LIGHT in patients with acute atherothrombotic stroke. Acta Neurol Scand. 2008;118:256-9 pubmed publisher
Dhawan P, Su Y, Thu Y, Yu Y, Baugher P, Ellis D, et al. The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells. J Biol Chem. 2008;283:15399-408 pubmed publisher
Celik S, Langer H, Stellos K, May A, Shankar V, Kurz K, et al. Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium. Thromb Haemost. 2007;98:798-805 pubmed
Otterdal K, Smith C, Oie E, Pedersen T, Yndestad A, Stang E, et al. Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes. Blood. 2006;108:928-35 pubmed
Edwards J, Sun S, Locklin R, Shipman C, Adamopoulos I, Athanasou N, et al. LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis. Arthritis Rheum. 2006;54:1451-62 pubmed

product information

master code :

DLIT00

SKU :

DLIT00

product name :

Human LIGHT/TNFSF14 Quantikine ELISA Kit

unit size :

1 Kit

description :

The Human LIGHT/TNFSF14 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies human LIGHT/TNFSF14 in cell culture supernates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul), saliva (25 ul).

target :

LIGHT/TNFSF14

category :

ELISAs

species :

Human

specificity :

Natural and recombinant human LIGHT

gene symbol :

TNFSF14

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL), Saliva (25 uL)

elisaSensitivity :

16.5 pg/mL

elisaRange :

31.20 - 2000 pg/mL

top caption :

Human LIGHT/TNFSF14 ELISA Calibrator Diluent RD5K Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Human LIGHT Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human LIGHT in cell culture supernates, serum, plasma, and saliva. It contains NS0-expressed recombinant human LIGHT and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human LIGHT showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human LIGHT.

alt names :

CD258, CD258 antigen, delta transmembrane LIGHT, Herpes virus entry mediator ligand, Herpesvirus entry mediator ligand, HVEM-L, HVEMLherpesvirus entry mediator-ligand, ligand for herpesvirus entry mediator, LIGHTherpesvirus entry mediator A, LTg, TNFSF14, TR2, tumor necrosis factor (ligand) superfamily, member 14, tumor necrosis factor ligand superfamily member 14, tumor necrosis factor receptor-like 2, tumor necrosis factor superfamily member LIGHT

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.