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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Human LIF Quantikine ELISA Kit
catalog :
DLF00B
quantity :
1 Kit
price :
655 USD
citations: 19
Reference
Xu S, Yang X, Chen Q, Liu Z, Chen Y, Yao X, et al. Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis. EBioMedicine. 2022;86:104312 pubmed publisher
Li H, Yao J, Chang X, Wu J, Duan T, Wang K. LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia. Reproduction. 2018;155:297-306 pubmed publisher
da Costa S, Roela R, Junqueira M, Arantes C, Brentani M. The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes. Leuk Res. 2010;34:507-12 pubmed publisher
Xiao Y, Sun X, Yang X, Zhang J, Xue Q, Cai B, et al. Leukemia inhibitory factor is dysregulated in the endometrium and uterine flushing fluid of patients with adenomyosis during implantation window. Fertil Steril. 2010;94:85-9 pubmed publisher
Evans J, Catalano R, Brown P, Sherwin R, Critchley H, Fazleabas A, et al. Prokineticin 1 mediates fetal-maternal dialogue regulating endometrial leukemia inhibitory factor. FASEB J. 2009;23:2165-75 pubmed publisher
Bronte Tinkew D, Terebiznik M, Franco A, Ang M, Ahn D, Mimuro H, et al. Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo. Cancer Res. 2009;69:632-9 pubmed publisher
Xu J, Yasui N, Ikeda K, Pan W, Watanabe J, Shiotani M, et al. Isoflavones regulate secretion of leukemia inhibitory factor and transforming growth factor {beta} and expression of glycodelin in human endometrial epithelial cells. J Endocrinol. 2008;196:425-33 pubmed publisher
Duluc D, Delneste Y, Tan F, Moles M, Grimaud L, Lenoir J, et al. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Blood. 2007;110:4319-30 pubmed
Kamohara H, Ogawa M, Ishiko T, Sakamoto K, Baba H. Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression. Int J Oncol. 2007;30:977-83 pubmed
Zhang Y, Taveggia C, MELENDEZ VASQUEZ C, Einheber S, Raine C, Salzer J, et al. Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. J Neurosci. 2006;26:12174-85 pubmed
Wunder D, Mueller M, Birkhäuser M, Bersinger N. Increased ENA-78 in the follicular fluid of patients with endometriosis. Acta Obstet Gynecol Scand. 2006;85:336-42 pubmed
Hirota H, Izumi M, Hamaguchi T, Sugiyama S, Murakami E, Kunisada K, et al. Circulating interleukin-6 family cytokines and their receptors in patients with congestive heart failure. Heart Vessels. 2004;19:237-41 pubmed
López Karpovitch X, Barrales Benitez O, Flores M, Piedras J. Effect of azacytidine in the release of leukemia inhibitory factor, oncostatin m, interleukin (IL)-6, and IL-11 by mononuclear cells of patients with refractory anemia. Cytokine. 2002;20:154-62 pubmed
Nakao T, Kim S, Ohta K, Kawano H, Hino M, Miura K, et al. Role of mitogen-activated protein kinase family in serum-induced leukaemia inhibitory factor and interleukin-6 secretion by bone marrow stromal cells. Br J Pharmacol. 2002;136:975-84 pubmed
Chen C, Yang J, Lin K, Chao K, Ho H, Yang Y. The significance of cytokines, chemical composition, and murine embryo development in hydrosalpinx fluid for predicting the IVF outcome in women with hydrosalpinx. Hum Reprod. 2002;17:128-33 pubmed
Rockman S, Demmler K, Roczo N, Cosgriff A, Phillips W, Thomas R, et al. Expression of interleukin-6, leukemia inhibitory factor and their receptors by colonic epithelium and pericryptal fibroblasts. J Gastroenterol Hepatol. 2001;16:991-1000 pubmed
Carstanjen D, Regenfus M, Muller C, Salama A. Interleukin-6 is a major effector molecule of short-term G-CSF treatment inducing bone metabolism and an acute-phase response. Exp Hematol. 2001;29:812-21 pubmed
Loeuillet C, Bernard G, Remy Martin J, Saas P, Herve P, Douay L, et al. Distinct hematopoietic support by two human stromal cell lines. Exp Hematol. 2001;29:736-45 pubmed
Carnegie J, Morgan J, McDiarmid N, Durnford R. Influence of protein supplements on the secretion of leukaemia inhibitory factor by mitomycin-pretreated Vero cells: possible application to the in vitro production of bovine blastocysts with high cryotolerance. J Reprod Fertil. 1999;117:41-8 pubmed
product information
master code :
DLF00B
SKU :
DLF00B
product name :
Human LIF Quantikine ELISA Kit
unit size :
1 Kit
description :
The Human LIF Quantikine ELISA Kit from R&D Systems quantifies human LIF in cell culture supernates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul).
target :
LIF
category :
ELISAs
species :
Human
specificity :
Natural and recombinant human LIF.
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
elisaSensitivity :
5.36 pg/mL
elisaRange :
31.30 - 2000 pg/mL
top caption :
Human LIF ELISA Cell Culture Supernate Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine« Human LIF Immunoassay is a 4.5 hours solid phase ELISA designed to measure human LIF in cell culture supernates, serum, and plasma. It contains HEK293-expressed recombinant human LIF and antibodies raised against the recombinant protein. Results obtained for naturally occurring human LIF showed linear curves that were parallel to the standard curves obtained using the recombinant Quantikine« kit standards. These results indicate that this kit can be used to determine relative mass values for natural human LIF.
alt names :
CDF, D factor, DIA, differentiation inhibitory activity, differentiation stimulating factor, Differentiation-stimulating factor, Emfilermin, HILDA, HILDAcholinergic differentiation factor, leukemia inhibitory factor, leukemia inhibitory factor (cholinergic differentiation factor), Melanoma-derived LPL inhibitor, MLPLI
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.