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company name :
R&D Systems
product type :
ELISA/assay
product name :
Human Total IL-18/IL-1F4 Quantikine ELISA Kit
catalog :
DL180
quantity :
1 Kit
price :
655 USD
more info or order :
citations: 25
Reference
Martinez Valenzuela L, Vidal Alabr xf3 A, Rubio B, Ant xf3 n P xe0 mpols P, G xf3 mez Preciado F, Fulladosa X, et al. Evaluating Single-Nucleotide Polymorphisms in Inflammasome Proteins and Serum Levels of IL-18 and IL-1β in Kidney Interstitial Damage in Anti-Neutrophilic Cytoplasmic Antibody-Associated Vasculitis. Int J Mol Sci. 2024;25: pubmed publisher
Neubauer Geryk J, Wielicka M, My x15b liwiec M, Zorena K, Bieniaszewski L. The Impact of Metabolic Memory on Immune Profile in Young Patients with Uncomplicated Type 1 Diabetes. Int J Mol Sci. 2024;25: pubmed publisher
Kosmider O, Poss xe9 m xe9 C, Templ xe9 M, Corneau A, Carbone F, Duroyon E, et al. VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation. Nat Commun. 2024;15:910 pubmed publisher
Exconde P, Hernandez Chavez C, Bourne C, Richards R, Bray M, Lopez J, et al. The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases. Cell Rep. 2023;42:113581 pubmed publisher
Musia x142 K, Stojanowski J, Mi x15b kiewicz Bujna J, Ka x142 wak K, Ussowicz M. KIM-1, IL-18, and NGAL, in the Machine Learning Prediction of Kidney Injury among Children Undergoing Hematopoietic Stem Cell Transplantation-A Pilot Study. Int J Mol Sci. 2023;24: pubmed publisher
Nabatanzi R, Ssekamatte P, Castelnuovo B, Kambugu A, Nakanjako D. Increased Levels of Caspase-1 and IL-1β Among Adults With Persistent Immune Activation After 12 Years of Suppressive Antiretroviral Therapy in the Infectious Diseases Institute HIV Treatment Cohort. Open Forum Infect Dis. 2023;10:ofad539 pubmed publisher
Schnittman S, Kitch D, Swartz T, Burdo T, Fitch K, McCallum S, et al. Coronary Artery Plaque Composition and Severity Relate to the Inflammasome in People With Treated Human Immunodeficiency Virus. Open Forum Infect Dis. 2023;10:ofad106 pubmed publisher
Willems L, Jacobs L, Groh L, ten Cate H, Spronk H, Wilson Storey B, et al. Vascular Function, Systemic Inflammation, and Coagulation Activation 18 Months after COVID-19 Infection: An Observational Cohort Study. J Clin Med. 2023;12: pubmed publisher
Milara J, Mart xed nez Exp xf3 sito F, Montero P, Roger I, Bayarri M, Ribera P, et al. N-acetylcysteine Reduces Inflammasome Activation Induced by SARS-CoV-2 Proteins In Vitro. Int J Mol Sci. 2022;23: pubmed publisher
Szczepanik Ku x142 ak P, Michalska Jakubus M, Kowal M, Krasowska D. Serum Levels of Selected IL-1 Family Cytokines in Patients with Morphea. J Clin Med. 2022;11: pubmed publisher
Chiang M, Nicol C, Lo S, Hung S, Wang C, Lin C. Resveratrol Mitigates Oxygen and Glucose Deprivation-Induced Inflammation, NLRP3 Inflammasome, and Oxidative Stress in 3D Neuronal Culture. Int J Mol Sci. 2022;23: pubmed publisher
Piancone F, La Rosa F, Marventano I, Hernis A, Miglioli R, Trecate F, et al. Modulation of Neuroendocrine and Immunological Biomarkers Following Rehabilitation in Sarcopenic Patients. Cells. 2022;11: pubmed publisher
La Rosa F, Zoia C, Bazzini C, Bolognini A, Saresella M, Conti E, et al. Modulation of MAPK- and PI3/AKT-Dependent Autophagy Signaling by Stavudine (D4T) in PBMC of Alzheimer's Disease Patients. Cells. 2022;11: pubmed publisher
Rosen D, Murphy E, Gejman R, Capili A, Friedlander R, Rand S, et al. Cytokine response over the course of COVID-19 infection in pregnant women. Cytokine. 2022;154:155894 pubmed publisher
Tominaga T, Ikemura T, Yada K, Kanda K, Sugama K, Ma S, et al. The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males. Antioxidants (Basel). 2021;10: pubmed publisher
La Rosa F, Agostini S, Saresella M, Costa A, Piancone F, Miglioli R, et al. Deregulation of IL-37 and its miRNAs modulators in sarcopenic patients after rehabilitation. J Transl Med. 2021;19:172 pubmed publisher
Matias M, Romão Veiga M, Ribeiro V, Nunes P, Gomes V, Devides A, et al. Progesterone and vitamin D downregulate the activation of the NLRP1/NLRP3 inflammasomes and TLR4-MyD88-NF-κB pathway in monocytes from pregnant women with preeclampsia. J Reprod Immunol. 2021;144:103286 pubmed publisher
de Graaf D, Jaeger M, van den Munckhof I, Ter Horst R, Schraa K, Zwaag J, et al. Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects. Eur J Immunol. 2021;51:662-671 pubmed publisher
Tsugawa H, Kabe Y, Kanai A, Sugiura Y, Hida S, Taniguchi S, et al. Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasome complex to prevent Salmonella infection. PLoS Biol. 2020;18:e3000813 pubmed publisher
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Kim S, Lee S, Kim S, Kim J, Choi E, Cho W, et al. SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease. Nat Commun. 2020;11:2127 pubmed publisher
Janks L, Sharma C, Egan T. A central role for P2X7 receptors in human microglia. J Neuroinflammation. 2018;15:325 pubmed publisher
Qian L. Decreased interleukin-11 levels in the semen of infertile males. Cytokine. 2018;108:57-59 pubmed publisher
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image
image 1 :
R&D Systems DL180 image 1
Human Total IL-18 ELISA Cell Culture Supernate/Urine Standard Curve
product information
brand :
R&D Systems
catalog number base :
DL180
SKU :
DL180
product name :
Human Total IL-18/IL-1F4 Quantikine ELISA Kit
units size :
1 Kit
description :
The Human Total IL-18/IL-1F4 Quantikine ELISA Kit from R&D Systems quantifies human IL-18/IL-1F4 in cell culture supernates (50 ul), serum (17 ul), edta plasma (17 ul), heparin plasma (17 ul), saliva (25 ul), urine (50 ul).
target :
IL-18/IL-1F4
category :
ELISAs
all_available conjugate :
HRP
species :
Human
specificity :
Natural and recombinant human Total IL-18.
assay length :
4.0 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (17 uL), EDTA Plasma (17 uL), Heparin Plasma (17 uL), Saliva (25 uL), Urine (50 uL)
elisaSensitivity :
5.15 pg/mL
elisaRange :
15.60 - 1000 pg/mL
top caption :
Human Total IL-18 ELISA Cell Culture Supernate/Urine Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine® Human Total IL-18/IL-1F4 Immunoassay is a 4.0 hour solid-phase ELISA designed to measure human IL-18 in cell culture supernates, serum, plasma, saliva, and urine. It contains E. coli-expressed recombinant human IL-18 and has been shown to accurately quantitate the recombinant factor free and in complex with IL-18 BPa. Results obtained using natural human IL-18 showed linear curves that were parallel to the standard curves obtained using the Quantikine® kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-18.
alt names :
Iboctadekin, IFN-gamma-inducing factor, IGIF, IGIFIL-1 gamma, IL18, IL-18MGC12320, IL-1F4, IL1F4iboctadekin, IL-1g, Interferon gamma-inducing factor, interleukin 18 (interferon-gamma-inducing factor), Interleukin-1 gamma, interleukin-18
storage :
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.